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Muscle sarcomas and alopecia in A/J mice chronically treated with nicotine.

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OBJECTIVE To evaluate the pathobiologic effects of long-term treatment with nicotine of A/J mice susceptible to tobacco-induced lung carcinogenesis. METHODS Experimental group of mice received subcutaneous injections of the LD(50) dose of (-)nicotine hydrogen tartrate of 3 mg/kg/day, 5 days per week

Frontal fibrosing alopecia and environment: may tobacco be protective?

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Permanent alopecia after cranial irradiation: dose-response relationship.

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OBJECTIVE To develop a dose-response relationship for the occurrence of permanent alopecia after cranial irradiation and to analyze potential confounding variables that may contribute to this unwanted and often unavoidable complication of treatment. METHODS Twenty-six patients were enrolled in this

Implications of Cigarette Smoking on Early Onset Androgenetic Alopecia: A Cross Sectional Study

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Androgenetic alopecia (AGA) is a condition affecting both males and females. We aimed to asses the demographic and clinical features of early-onset AGA among smokers and non smokers and to evaluate if prevalence of AGA was affected by smoking. One thousand (1000) healthy males aged between 20-35

Induction of alopecia in mice exposed to cigarette smoke.

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Besides being responsible for a high proportion of those chronic degenerative diseases that are the leading causes of death in the population, tobacco smoking has been associated with skin diseases. Smoke genotoxicants are metabolized in hair follicle cells, where they form DNA adducts and cause DNA

An Analysis of the Correlation between Alopecia and Chief Complaints.

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OBJECTIVE In this study, we measured the extent of ten levels of classified symptoms by 300 (male and female) patients visiting the hair loss clinics of "S" hospitals in Gangbuk and Gangnam between January 2009 and June 2011 by analyzing the patients' chief complaints. METHODS The method of

The Influence of Various Parameters on the Success of Sensor-Controlled Scalp Cooling in Preventing Chemotherapy-Induced Alopecia.

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BACKGROUND The influence of systemic comorbidities on the success of scalp cooling during chemotherapy (CT) is widely unexplored. Comorbidities often require additional medication which itself can occasionally cause alopecia. This study investigates the influence of selected parameters on the

Tobacco and the skin.

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Smoking negatively impacts the health of the skin as it does every organ system. This contribution reviews the effect of cigarette smoking on wound healing, wrinkling, and aging of the skin, skin cancer, psoriasis, and other inflammatory skin diseases, hidradenitis suppurativa, acne, alopecia, lupus

Tobacco smoke causes premature skin aging.

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Smoking tobacco is the most preventable cause of morbidity and is responsible for more than three million deaths a year worldwide. In addition to a strong association with a number of systemic diseases, smoking is also associated with many dermatological conditions, including poor wound healing,

Risk Factors for Frontal Fibrosing Alopecia: a case-control study in a multiracial population

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Background: Frontal fibrosing alopecia (FFA) is a chronic cicatricial alopecia with unknown etiology and a worldwide rising incidence. Objective: The objective of this study

Association between smoking and hair loss: another opportunity for health education against smoking?

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Besides being the single most preventable cause of significant morbidity and an important cause of death in the general population, tobacco smoking has been associated with adverse effects on the skin. Smoke-induced premature skin ageing has attracted the attention of the medical community, while

Dermatological aspects of synthetic cannabinoid addiction.

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BACKGROUND Synthetic cannabinoids (SCs) have recently become one of the most abused substances among young population and have caused severe health consequences in our country and worldwide. OBJECTIVE The aim of this study was to investigate sociodemographic and dermatological findings in SC

The epidemiology of benign prostatic hyperplasia: a study in Greece.

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OBJECTIVE To assess the epidemiology of benign prostatic hyperplasia (BPH) in a case-control study in greater Athens, Greece. METHODS The study comprised 184 patients surgically treated for BPH within one year of its diagnosis (cases) and 246 patients with no symptoms of BPH who were treated in the

Risk factors for prostate cancer: a case-control study in Greece.

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A case-control study of prostate cancer (PC) was undertaken in Athens, Greece. Cases were 320 patients with histologically confirmed incident disease, whereas controls were 246 patients without history or symptomatology of benign prostatic hyperplasia, treated in the same hospitals as the cases for

[Registration of suspected adverse effects by the Bureau Adverse Effects Drugs; research activities in 1993].

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In 1993, the Netherlands Centre for Monitoring of Adverse Reactions to Drugs received 1585 reports of suspected adverse reactions. The most important reports concerned myocardial infarction due to sumatriptan, cholestatic hepatitis due to itraconazole, agranulocytosis due to trazodone and bleeding

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