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anorexia/phosphatase

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Tartrate-resistant acid phosphatase (TRAP) exists as isoforms 5a and 5b. TRAP 5a is a biomarker of chronic inflammation and influences adipose tissue and 5b associates with bone metabolism/pathologies. The aim was to investigate the association of serum TRAP 5a/5b isoforms with fat and
Anorexia nervosa (AN) is a very extended pathology among adolescent girls nowadays. These patients show a high degree of osteopenia; hence, study of their bone remodelling is of great interest. Serum bone alkaline phosphatase (bAP) and aminoterminal propeptide of procollagen I (PINP) provide good

A prospective study of changes in bone turnover and bone density associated with regaining weight in women with anorexia nervosa.

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Anorexia nervosa (AN) is a condition of self-induced weight loss, associated with an intense fear of gaining weight. Previous studies have shown that bone density may increase with regaining and maintaining normal weight; however, relatively little is known about the changes in bone metabolism that

Changes in bone turnover markers and menstrual function after short-term oral DHEA in young women with anorexia nervosa.

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Bone loss is a serious consequence of anorexia nervosa (AN). Subnormal levels of serum dehydroepiandrosterone (DHEA) are seen in patients with AN and may be causally linked to their low bone density. We hypothesized that oral DHEA would decrease markers of bone resorption (urinary N-telopeptides

Evolution of serum biochemical indicators in anorexia nervosa patients: a 1-year follow-up study.

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BACKGROUND Long-term studies on the evolution of serum biochemical indicators in anorexia nervosa (AN) patients during treatment are lacking in the literature. Thus, a 1-year follow-up of serum biochemical parameters in a homogeneous group of AN patients was performed. METHODS Fourteen

Increased Bone Mineral Content During Rapid Weight Gain Therapy in Anorexia Nervosa.

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Patients with anorexia nervosa (AN) are at high risk of reduced bone mass. Osteocalcin (OC), a bone formation marker, has been proposed to act as a link between bone and energy metabolism. We investigated how the 3 forms of OC respond during a 12-week intensive nutrition therapy in AN patients, in

Skeletal status and laboratory investigations in adolescent girls with anorexia nervosa.

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To our knowledge anorexia nervosa (AN) adversely influences bone density, but whether qualitative characteristics of bone are also affected is not known. For this reason we investigated prospectively the changes in skeletal status in a population of 18 adolescent girls with AN aged 11.5-18.1 years

Biochemical abnormalities of the serum in anorexia nervosa.

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Biochemical analyses of sera from 27 patients with anorexia nervosa were performed and compared with those of normal female volunteers and other anorectic groups including patients who had undergone digestive tract surgery and patients with malignancies. There were significant increases in

Ectopic germinoma in the corpus callosum with severe restrictive anorexia: case report and review of literature.

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Intracranial germ cell tumors are a rare group of neoplasms constituting 1% to 2% of primary intracranial tumors in North America and Europe. Germinomas of the corpus callosum are exceedingly rare, accounting for only 0.7% of all intracranial germ cell tumors. We report a case of germinoma in the

Paradoxical increase of plasma vitamin B12 and folates with disease severity in anorexia nervosa.

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OBJECTIVE Anorexia nervosa (AN) is a complex disorder involving severe psychological manifestations and multiple organ damage, including liver dysfunction. The primary aim of this study consisted in assessing plasma levels of vitamin B12 and folates with respect to liver function enzymes considering

Bone mineral density and anorexia nervosa in women.

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OBJECTIVE A review of reports of reduced bone mineral density in women with anorexia nervosa was undertaken in order to profile specific risk factors, which could then be used as the basis for suggestions for future research and treatment. METHODS Thirteen research studies and four case studies of

[Bone metabolism in adolescent girls with short course of anorexia nervosa].

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OBJECTIVE The objective of this study was to determine the prevalence of bone mass reduction and determine its causes in young girls with short course of anorexia nervosa (AN). METHODS Bone mineral density (BMD)of lumber spine by dual energy x-ray absorptiometry, total alkaline phosphatase (TAP),

Osteomalacia in a patient with severe anorexia nervosa.

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A 27-year-old woman with anorexia nervosa since adolescence was referred to our unit for generalized bone pain most severe at the pelvis and an inability to stand. She reported a pelvic fracture diagnosed one year earlier, which had failed to heal. Laboratory tests showed low serum phosphate, normal

Amenorrhea after weight recover in anorexia nervosa: role of body composition and endocrine abnormalities.

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Hypothalamic amenorrhea in anorexia nervosa often precedes weight loss and may persist after re-feeding and restoration of a stable normal weight. OBJECTIVE To assess the rate of persistent amenorrhea in anorexia nervosa (AN) after re-feeding and the relations of this condition with body composition

Changes in bone turnover in patients with anorexia nervosa during eleven weeks of inpatient dietary treatment.

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BACKGROUND Many adolescents with anorexia nervosa suffer from severe osteopenia and osteoporosis. We hypothesized that individualized nutrition therapy may improve bone turnover in anorectic patients. METHODS We studied 19 female patients [mean age, 14.2 +/- 1.4 years; mean body weight, 39.3 +/- 5.4
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