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Polymorphisms in endothelin system genes, arsenic levels and obesity risk.

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OBJECTIVE Obesity has been linked to morbidity and mortality through increased risk for many chronic diseases. Endothelin (EDN) system has been related to endothelial function but it can be involved in lipid metabolism regulation: Receptor type A (EDNRA) activates lipolysis in adipocytes, the two

Arsenic methylation capacity and obesity are associated with insulin resistance in obese children and adolescents.

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The goal of the present study was to compare the arsenic methylation capacities in elementary school and junior high school students in an area of Taiwan with low arsenic exposure, and explore the influence of both arsenic methylation capacity and obesity on insulin resistance in these children and

[The potentials for the balneotherapy of obesity using arsenic-containing mineral water].

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Arsenic mineral water from the Sinegorsk springs was tried in the treatment of experimental alimentary obesity in rat Wistar males and patients with exogenous-constitutional obesity. Body mass, blood lipids, hepatic neutral lipids, glucose-6-phosphate-dehydrogenase were measured. Arsenic mineral

Arsenic and Obesity: a Review of Causation and Interaction

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ass="sub-title"> Purpose of review: Arsenic is associated with cancer, heart disease, diabetes, and other outcomes that are also related to obesity. These similar effects raise the possibility that arsenic plays a role in obesity causation. They also

What is the role of obesity in the aetiology of arsenic-related disease?

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Consumption of arsenic contaminated drinking water causes a large variety of adverse health outcomes. Body mass index (BMI), which is linked to diet, is positively associated with arsenic methylation capacity. We investigated the association between an obesity-related diet and arsenic body burden

Adiponectin gene polymorphisms and obesity increase the susceptibility to arsenic-related renal cell carcinoma.

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Our recent study found that high urinary total arsenic levels were associated with renal cell carcinoma (RCC). Recent studies demonstrated that low circulating adiponectin was related to RCC. The aim of the present study was to explore the relationship between adiponectin gene (ADIPOQ) polymorphisms

Arsenic and Obesity: A Comparison of Urine Dilution Adjustment Methods.

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A commonly used approach to adjust for urine dilution in analyses of biomarkers is to adjust for urinary creatinine. However, creatinine is a product of muscle mass and is therefore associated with body mass. In studies of urinary analytes and obesity or obesity-related outcomes, controlling for

The relationship between obesity, insulin and arsenic methylation capability in Taiwan adolescents.

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OBJECTIVE This study evaluated the arsenic methylation profile of adolescents and explored the influence of body mass index (BMI) on the arsenic methylation profile of adolescents in an area of Taiwan with no-obvious arsenic exposure. METHODS This study evaluated 202 normal weight students and 101

The role of arsenic in obesity and diabetes.

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As many individuals worlwide are exposed to arsenic, it is necessary to unravel the role of arsenic in the risk of obesity and diabetes. Therefore, the present study reviewed the effects of arsenic exposure on the risk and potential etiologic mechanisms of obesity and diabetes. It has been suggested

Oligofructose protects against arsenic-induced liver injury in a model of environment/obesity interaction.

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Arsenic (As) tops the ATSDR list of hazardous environmental chemicals and is known to cause liver injury. Although the concentrations of As found in the US water supply are generally too low to directly damage the liver, subhepatotoxic doses of As sensitize the liver to experimental NAFLD. It is now

Obesity and excess weight in early adulthood and high risks of arsenic-related cancer in later life.

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BACKGROUND Elevated body mass index (BMI) is a risk factor for cardiovascular disease, diabetes, cancer, and other diseases. Inflammation or oxidative stress induced by high BMI may explain some of these effects. Millions of people drink arsenic-contaminated water worldwide, and ingested arsenic has

Obesity and increased susceptibility to arsenic-related type 2 diabetes in Northern Chile.

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BACKGROUND The prevalence of type 2 diabetes (T2D) has nearly doubled since 1980. Elevated body mass index (BMI) is the leading risk factor for T2D, mediated by inflammation and oxidative stress. Arsenic shares similar pathogenic processes, and may contribute to hyperglycemia and β-cell

Multicenter evaluation of arsenic trioxide dosing in obese patients with low-intermediate risk acute promyelocytic leukemia.

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Risk factors of lipid metabolism disorders in residents of multi-environmental exposure to cadmium and arsenic.

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The authors evaluated negative effects of cadmium and arsenic compounds on health of population residing near storage of extraction and processing waste of ore mining and processing enterprise. Hygienic analysis covered quality of ambient air, drinkable water and foods, evaluation of risk factors of

Inverse association between toenail arsenic and body mass index in a population of welders.

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Recent data show that arsenic may play a role in obesity-related diseases. However, urinary arsenic studies report an inverse association between arsenic level and body mass index (BMI). We explored whether toenail arsenic, a long-term exposure measure, was associated with BMI in 74 welders with

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