asphyxia/albumină

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Cord blood ischemia-modified albumin: is it associated with abnormal Doppler findings in complicated pregnancies and predictive of perinatal asphyxia?

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OBJECTIVE To evaluate the significance of the cord blood ischemia-modified albumin (IMA) level as a diagnostic marker for perinatal asphyxia and to determine the associations of IMA levels with the complexity of pregnancy and abnormal Doppler findings, regardless of perinatal asphyxia. METHODS This

Ischemia-modified albumin (IMA): could it be useful to predict perinatal asphyxia?

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Perinatal asphyxia is a significant cause of perinatal morbidity and mortality worldwide. It is estimated that around 23% of all newborn deaths are caused by birth asphyxia. Each year, between four and nine million newborns develop birth asphyxia worldwide, according to the World Health Organization

Increased permeability of the capillaries of the rat heart to plasma albumin with asphyxiation and with perfusion.

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1. Studies on the rate of efflux from the isolated perfused rat heart of plasma albumin conjugated with Evans Blue showed the conjugate to have penetrated extensively the extravascular compartment of the organ during a period of 2 min. This was confirmed by direct analysis of hearts for Evans Blue

Effect of asphyxia due to umbilical cord occlusion in the foetal lamb on leakage of liquid from the circulation and on permeability of lung capillaries to albumin.

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1. Experiments were performed on foetal lambs, exteriorized at Caesarean section, to determine the effects of asphyxia on the leakage of liquid from the circulation and on the permeability of lung capillaries to albumin. Following a period of control observation (30-120 min) the foetus was

Nitrated plasma albumin as a marker of nitrative stress and neonatal encephalopathy in perinatal asphyxia.

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Reactive nitrogen species (RNS) have been shown to play a major role in the pathophysiology of hypoxic-ischemic cerebral injury. Using a novel sensitive ELISA allowing the quantification of nitrated albumin (nitroalbumin) in plasma, we tested the hypothesis that perinatal asphyxia increases

[Effects of birth asphyxia or intrauterine distress on renal functions in newborns in the first week of life].

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OBJECTIVE To investigate the renal function in newborns with birth asphyxia or intrauterine distress in the first week of life. METHODS Sixty full-term newborns born between June 2002 and February 2003 were assigned into three groups: Control group (healthy newborns), Intrauterine distress group

Pressure passive cerebral blood flow and breakdown of the blood-brain barrier in experimental fetal asphyxia.

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Cerebral blood flow (CBF) was studied in non-exteriorized near-term sheep fetuses using the radioactive microsphere technique. By partially occluding the umbilical vessels for a period of 1--1 1/2 hours a progressive and severe asphyxia with a final arterial pH of 6.90 was achieved. Varying the mean

Risk factors for unexpected death from suffocation in elderly patients hospitalized for pneumonia.

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OBJECTIVE Unexpected death from suffocation as a result of ortholaryngeal mucinous secretions or vomitus during recovery from pneumonia is devastating for patients, their families and medical professionals. This study aimed to determine the risk factors for unexpected death from suffocation in

Blood volume in newborn piglets: effects of time of natural cord rupture, intra-uterine growth retardation, asphyxia, and prostaglandin-induced prematurity.

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Blood volume (BV), red cell mass (RCM; Cr-51) and plasma volume (125I-labeled albumin) were measured in 205 piglets from 28 litters shortly after birth. Spontaneous cord rupture in healthy piglets occurred during delivery (n = 25) or within 190 sec of birth (n = 82). Spontaneous and induced delay of

Serum Ischemia-Modified Albumin in Preterm Babies with Respiratory Distress Syndrome.

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Infants with respiratory distress syndrome (RDS) may suffer from severe hypoxia, asphyxia. In this study, we aimed to evaluate serum ischemia-modified albumin (IMA) level as a diagnostic marker for hypoxia in preterm infants with RDS. Thirty-seven premature newborns with RDS were allocated as the

Polynitroxyl albumin and albumin therapy after pediatric asphyxial cardiac arrest: effects on cerebral blood flow and neurologic outcome.

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Postresuscitation cerebral blood flow (CBF) disturbances and generation of reactive oxygen species likely contribute to impaired neurologic outcome after pediatric cardiac arrest (CA). Hence, we determined the effects of the antioxidant colloid polynitroxyl albumin (PNA) versus albumin or normal

Association of neonatal respiratory distress with birth asphyxia and deficiency of red cell mass in premature infants.

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Red cell mass (RCM) was estimated using 125I-labelled human serum albumin in 128 premature infants born after 26 to 36 weeks gestation. Infants of three different gestational periods (26--29, 30--32, and 33--36 weeks) with respiratory distress (RD) averaged lower one-minute Apgar scores and lower

Effects of asphyxia on lung fluid balance in baby lambs.

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The purpose of this study was to assess the effects of combined hypoxia and hypercapnia and of severe asphyxia on lung water balance and protein transport in newborn lambs. We studied ten 2-4-wk-old anesthetized lambs which were mechanically ventilated first with air for 2-3 h, then with 10-12%

Cerebrovascular mechanisms in perinatal asphyxia: the role of vasogenic brain edema.

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Previous studies from our laboratory have demonstrated penetration of Evan's blue dye into the brain in profound fetal asphyxia, suggesting that vasogenic brain edema (BE) might be an immediate contributing factor in asphyxial brain injury. We modified the 125I-labeled albumin method of Pappius and

Association of cord blood ischemia-modified albumin level with abnormal foetal Doppler parameters in intrauterine growth-restricted foetuses.

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To investigate cord blood ischemia-modified albumin (IMA) levels in pregnancies with intrauterine growth restriction (IUGR) and to determine its association with abnormal fetal Doppler findings.Umbilical cord IMA levels were assessed in 34 pregnant women

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