asphyxia/hypoxia

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[Induction of hypoxia-inducible factor-1alpha in two kinds of rats asphyxiation death models].

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OBJECTIVE To investigate the expression of hypoxia-inducible factor 1-alpha (HIF1-alpha) in the heart, lung, liver and kidney in rats died of two typical models of asphyxia. METHODS Two asphyxia models were made and tissue samples of the dead rats were collected from different groups at various

Experiments on placental circulation and transplacental transfer in exteriorized foetuses in hypoxia and after asphyxia in guinea pigs.

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Experiments were carried out on near term pregnant guinea pigs. Cesarean section was performed and by exteriorization of the foetuses the placental stage of labor was simulated. In one group of foetuses, chosen at random, we induced hypoxia, and in an another series of experiments asphyxia, each

[Rate of excitation spread along a peripheral nerve in healthy infants in the 1st year of life and in infants who have had intrauterine hypoxia and asphyxia at birth].

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The velocity in the extension of excitation through the peripheral nerves was studied in 99 normal babies of the first year and in 135 children with intrauteral hypoxia and asphyxia during delivery. In children with perinatal lesions of the CNS there were changes in the absolute volumes of the

[Insulin activity of blood plasma in fetuses and newborn infants with asphyxia. Effect of insulin on the course of hypoxia and elimination of its sequelae under experimental conditions].

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In this clinico-experimental work data are presented concerning the blood plasma insulin activity in mature fetuses and neonates in asphyxia; the influence of insulin on the course of hypoxia and elimination of its sequelae under experimental conditions on the newborn and sexually mature rats was

The cerebral hemodynamic response to asphyxia and hypoxia in the near-term fetal sheep as measured by near infrared spectroscopy.

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This study examined the hypothesis that the cerebrovascular response to asphyxia of the late gestation sheep fetus is characterized by an increase in cerebrovascular resistance and a fall in cerebral blood flow (CBF) rather than the fall in resistance and increase in CBF which occurs in acute

Pre-existing hypoxia is associated with greater EEG suppression and early onset of evolving seizure activity during brief repeated asphyxia in near-term fetal sheep.

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Spontaneous antenatal hypoxia is associated with high risk of adverse outcomes, however, there is little information on neural adaptation to labor-like insults. Chronically instrumented near-term sheep fetuses (125 ± 3 days, mean ± SEM) with baseline PaO2 < 17 mmHg (hypoxic group: n = 8) or > 17

Chronic intermittent asphyxia impairs rat upper airway muscle responses to acute hypoxia and asphyxia.

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BACKGROUND Obstructive sleep apnea (OSA) is a major clinical disorder that is characterized by multiple episodes of upper airway obstruction due to the failure of the upper airway dilator muscles to maintain upper airway patency. This results in chronic intermittent asphyxia (CIA) due to repetitive

[Significance of Hypoxia-related microRNA for Estimating the Cause of Mechanical Asphyxia Death].

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Under hypoxia condition, microRNA （miRNA） can interact with transcription factors for regulating the cell metabolism, angiogenesis, erythropoiesis, cellular proliferation, differentiation and apoptosis. The biological processes above may play an important role in mechanical asphyxia death. This

Vascular response to short-term systemic hypoxia, hypercapnia, and asphyxia in the cat.

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Acute systemic hypoxia, hypercapnia, or asphyxia was produced in ketamine-anesthetized, paralyzed cats by ventilating them for 2-4 min with appropriate gas mixtures. A sustained rise in arterial pressure occurred in all cases. Vascular responses to hypoxia (7% O2, 10% 02, or 14% O2) included muscle

[Pathophysiology of circulatory regulation in hypoxia and asphyxia in the perinatal period].

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Asphyxia is defined as hypoxia with hypercapnia; the physiology and pathophysiology of the O2-saturation-curve in maternal and fetal blood is given. Recent results about the redistribution of the cardiac output in chronically instrumented fetal lambs under the conditions of asphyxia, hypoxia and

Upper airway EMG responses to acute hypoxia and asphyxia are impaired in streptozotocin-induced diabetic rats.

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Obstructive sleep apnoea (OSA) is a major clinical disorder that is characterised by multiple episodes of upper airway obstruction due to failure of the upper airway dilator muscles to maintain upper airway patency. The incidence of OSA is high in many endocrine disorders including both

Plasma metabolite score correlates with Hypoxia time in a newly born piglet model for asphyxia.

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Hypoxic-ischemic encephalopathy (HIE) secondary to perinatal asphyxia is a leading cause of mortality and acquired long-term neurologic co-morbidities in the neonate. The most successful intervention for the treatment of moderate to severe HIE is moderate whole body hypothermia initiated within 6h

Cortical oxidative metabolism under conditions of ischemia, hypoxia, and asphyxia in the rabbit.

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The purpose of this investigation was to compare the effects of hypoxia, asphyxia, and ischemia on brain cortical oxidative metabolism. This study was carried out using 14 New Zealand White rabbits. The effects of episodic stress were measured simultaneously on brain functional metabolism by

[An immunochemical analysis of the function of the hemato-encephalic barrier in acute fetal hypoxia and asphyxia neonatorum].

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The neurospecific protein alpha 1-globulin has been assayed in serum in order to evaluate the blood-brain barrier in newborns with acute intrapartum hypoxia. The study involved 35 term newborns with birth asphyxia of variable severity. The alpha 1-globulin levels correlated with severity of

Cerebral energy metabolism in diving and non-diving birds during hypoxia and apnoeic asphyxia.

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1. Cerebral energy metabolism during apnoeic asphyxia and steady-state hypoxia was compared in ducks and chickens; ducks tolerate apnoeic asphyxia 3-8 times longer than chickens. 2. Fluctuations in the reduced form of respiratory chain nicotinamide adenine dinucleotide (NADH) were monitored from the

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