balkan nephropathy/edema

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Renal MRI findings and their clinical associations in nephropathia epidemica: analysis of quantitative findings.

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Morphologic renal magnetic resonance imaging (MRI) findings in patients with nephropathia epidemica (NE) were evaluated, and these findings were correlated with the clinical course of NE. Renal MRI was performed in 20 hospitalized NE patients during the acute phase of their disease. A repeat MRI

Ocular characteristics in nephropathia epidemica or Puumala virus infection.

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OBJECTIVE We documented the largest series so far concerning the ocular characteristics of nephropathia epidemica. METHODS A total of 37 consecutive nephropathia epidemica patients underwent a comprehensive ophthalmic examination during hospitalization for systemic infection, and a control

[Comparative morphological evaluation of the changes in the early and late stages of endemic nephropathy].

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A comparative evaluation of the morphological changes from the early and late stages of endemic nephropathy is made on the base of biopsy and necropsy material. Thickened basal membranes partial obstruction and microaneurysms of the capillary of glomeruli are established during the early and late

Acute glaucoma in hemorrhagic fever with renal syndrome (nephropathia epidemica).

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Bilateral eyelid edema, chemosis, conjunctival injection and hemorrhages, shallowing of the anterior chamber with transitory myopia, and acute glaucoma were observed in three patients with hemorrhagic fever with renal syndrome (nephropathia epidemica). One patient had anterior uveitis with posterior

Four fatal cases of nephropathia epidemica.

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Four serologically confirmed fatal cases of nephropathia epidemica (NE), the mild form of hemorrhagic fever with renal syndrome (HFRS) are described. All the patients had disseminated intravascular coagulation. Autopsies revealed hemorrhage and necrotic areas of their pituitary glands, myocarditis,

An unusual cause of hypokalemic paralysis: aristolochic acid nephropathy with Fanconi syndrome.

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Aristolochic acid nephropathy (AAN) with Fanconi syndrome presenting as hypokalemic paralysis is extraordinarily rare and may be unrecognized. We describe a 41-year-old man who presented with the inability to ambulate upon awakening in the morning. Physical examination revealed symmetric paralysis

Pulmonary involvement in nephropathia epidemica: radiological findings and their clinical correlations.

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Nephropathia epidemica (NE) is a hemorrhagic fever with renal syndrome (HFRS) normally taking a benign clinical course. The etiologic agent, Puumala hantavirus is genetically closely related to Sin Nombre virus, which causes a frequently lethal febrile syndrome with pulmonary involvement (hantavirus

Nephropathia epidemica. The Scandinavian form of hemorrhagic fever with renal syndrome.

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We report epidemiologic, clinical, laboratory, and biopsy findings in 14 cases of nephropathia epidemica. The patients were between 19 and 49 years of age. The onset of the disease was characterized by high fever, nausea, headache, backache, abdominal pain, proteinuria, oliguria, hematuria, and

Probenecid prevents acute tubular necrosis in a mouse model of aristolochic acid nephropathy.

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Experimental aristolochic acid nephropathy is characterized by early tubulointerstitial injury followed by fibrosis, reproducing chronic lesions seen in humans. In vitro, probenecid inhibits aristolochic acid entry through organic anion transporters, reduces specific aristolochic acid-DNA adduct

Renal biopsy findings and clinicopathologic correlations in nephropathia epidemica.

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A series of 126 adult patients with a serologically confirmed diagnosis of nephropathia epidemica (NE) were studied during the acute phase of the disease. In 86 cases, renal biopsy was performed. The severity of renal failure correlated slightly with blood inflammatory parameters and the degree of

Nephropathia epidemica: mild variant of hemorrhagic fever with renal syndrome.

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The diagnosis of nephropathia epidemica (NE) is primarily not histological, but because biopsy samples sometimes reach the pathologist, knowledge of histology may be of diagnostic value, in addition to clarifying the pathogenesis. The authors collected 80 biopsies from 65 patients taken after the

Genetic, Genomic and Epigenomic Studies of Balkan Endemic Nephropathy (Ben).

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BEN is a primary, chronic tubulointerstitial nephritis characterized with chronic anemia, absence of edema, xantoderma, normal blood pressure and normal findings on the fundus oculi. The disease is distributed in restricted areas in Bulgaria, Romania, Croatia, Bosnia, Former Yugoslavia. Despite

[Acute hantavirus infection caused by a genetically newly identified viral strain. Severe and complicated course of hemorrhagic fever with renal syndrome (nephropathia epidemica)].

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METHODS A 49-year-old patient, a hobby hunter, fell ill acutely with joint and limb pain, abdominal pain, nausea and subfebrile temperatures. At hospitalization, the patient was in bad general condition, showing ascites and lid edema, and acute renal failure was diagnosed. METHODS Laboratory tests

[Hemorrhagic fever with renal syndrome. Apropos of 13 cases observed in Lorraine].

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Thirteen cases of hemorrhagic fever with renal syndrome (HFRS) have been observed in the Nancy area. Ten occurred during the summer of 1983 and three in April and May 1985. The clinical characteristics were in each case very typical: abrupt onset with high fever, myalgia, intense lumbar and

Young male patients are at elevated risk of developing serious central nervous system complications during acute Puumala hantavirus infection.

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BACKGROUND Our aim was to characterize clinical properties and laboratory parameters in patients with or without cerebrospinal fluid (CSF) findings suggestive of central nervous system (CNS) involvement, and especially those who developed serious CNS complications during acute nephropathia epidemica

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