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Prediction models for clustered data: comparison of a random intercept and standard regression model.

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BACKGROUND When study data are clustered, standard regression analysis is considered inappropriate and analytical techniques for clustered data need to be used. For prediction research in which the interest of predictor effects is on the patient level, random effect regression models are probably

The challenge of diagnosing Plasmodium ovale malaria in travellers: report of six clustered cases in French soldiers returning from West Africa.

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BACKGROUND Plasmodium ovale is responsible for 5% of imported malaria in French travellers. The clinical and biological features of six clustered cases of P. ovale malaria in an army unit of 62 French soldiers returning from the Ivory Coast are reported. METHODS All patients were symptomatic and

Ictal nausea with vomiting as the major symptom of simple partial seizures: electroencephalographic and magnetoencephalographic analysis.

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Autonomic symptoms and signs rarely occur as isolated phenomena without impaired consciousness. Ictal nausea with vomiting is a rare clinical manifestation of seizures. Ictal vomiting is considered a localizing sign in patients with partial seizures of temporal origin. We encountered two patients

Altered Hypothalamus-Pituitary-Adrenal Axis Function: A Potential Underlying Biological Pathway for Multiple Concurrent Symptoms in Patients with Advanced Lung Cancer.

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Patients with advanced cancer commonly experience multiple symptoms that present as groups or clusters. The present study aimed to examine whether hypothalamus-pituitary-adrenal (HPA) axis dysfunction underlies the concurrent multiple symptoms in patients with advanced cancer. METHODS Patients'

A Case Report of Mesenteric Panniculitis.

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A 33-year-old male with a past medical history of hypertension, migraine, depression, and alcohol abuse presented with complaints of nausea, vomiting, and abdominal pain. He was found to have an elevated lipase and ethanol level. CT scan of the abdomen was done which showed peripancreatic fat

Symptom clusters in patients with breast cancer receiving radiation therapy.

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Symptoms experienced by breast cancer patients often cluster together in groups known as "symptom clusters". The aim was to determine the symptom clusters in women with non-metastatic breast cancer treated by radiation therapy (RT).Edmonton

An outbreak of concurrent echovirus 30 and coxsackievirus A1 infections associated with sea swimming among a group of travelers to Mexico.

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BACKGROUND Enteroviruses are shed in human stool and can cause a wide spectrum of illness. They are the leading cause of aseptic meningitis. METHODS In 2004, the Connecticut Department of Public Health investigated a meningitis cluster among persons returning from a school-organized trip to

How to move pain and symptom research from the margin to the mainstream.

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Pain, dyspnea, nausea, and other physical symptoms receive rather little study despite their major public health impact and the similar neural circuitry that makes these symptoms tractable therapeutic targets. Pain accounts for more than 20% of medical visits and 10% of prescription drug sales but

Serpiginous gastric erosions caused by aspirin and other nonsteroidal antiinflammatory drugs.

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Erosive gastritis is a common disease, but no etiologic significance has been attributed to the size or shape of these gastric erosions. However, in 12 cases of erosive gastritis caused by aspirin (nine) and other nonsteroidal antiinflammatory drugs (NSAIDs) (indomethacin, two; naproxen, one)

Rare etiology of mechanical intestinal obstruction: Abdominal cocoon syndrome.

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Abdominal cocoon syndrome is a rare cause of intestinal obstruction with unknown etiology. Diagnosis of this syndrome, which can be summarized as the small intestine being surrounded by a fibrous capsule not containing the mesothelium, is difficult in the preoperative period. A 47-year-old male

Jejunal manometry in distal subacute mechanical obstruction: significance of prolonged simultaneous contractions.

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The aim of this study is to assess the value of jejunal manometry in the diagnosis of subacute mechanical obstruction distal to the proximal small bowel. In a retrospective review of 850 manometric tracings carried out in patients with unexplained nausea, vomiting, abdominal pain or altered bowel

Multidimensional constructs of the EORTC Quality of Life Questionnaire (QLQ-c30) in Korean cancer patients with heterogeneous diagnoses.

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OBJECTIVE The aim of this study was to evaluate the multidimensional constructs of the EORTC Quality of Life Questionnaire (QLQ-C30) in patients with cancer, employing not only the commonly used multitrait scaling analysis and interscale correlations, but also the factorial and multidimensional

Left Paraduodenal Hernia: Case Report of Rare Cause of Recurrent Abdominal Pain.

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Internal hernia is a relatively uncommon condition and is a rare type of intestinal obstruction. Paraduodenal hernia is considered the most common type of internal hernias. The rare prevalence and the variable symptoms make the clinical diagnosis of paraduodenal hernia a diagnostic challenge. We

Symptom clusters in patients with cancer in the hospice/palliative care setting.

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We determined commonly experienced symptoms reported by adult patients with cancer admitted to urban, ethnically diverse hospice settings and identified symptom clusters. We used hierarchical cluster analysis of 150 patients (41 % male, 20-92 years [M = 59, SD = 13.3], 51 % African American, 37 %

Gastro-intestinal poisoning due to consumption of daffodils mistaken for vegetables at commercial markets, Bristol, United Kingdom.

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BACKGROUND In February 2012, we investigated a cluster of people who presented at a local emergency department with sudden onset of vomiting after mistaken consumption of daffodils. METHODS We interviewed patients to collect information on daffodil purchase and consumption. With Local Authority we

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