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Mitigation of obesity-promoted diseases by Nigella sativa and thymoquinone.

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Obesity is closely associated with increased incidence of cardiovascular diseases, cancer, insulin resistance, and immune dysfunction, and thus obesity-mitigation strategies should take into account these secondary pathologies in addition to promoting weight loss. Recent studies indicate that black

Spices in a High-Saturated-Fat, High-Carbohydrate Meal Reduce Postprandial Proinflammatory Cytokine Secretion in Men with Overweight or Obesity: A 3-Period, Crossover, Randomized Controlled Trial.

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Postprandial inflammation that occurs concurrently with hyperglycemia and hyperlipidemia after ingestion of a high-saturated-fat, high-carbohydrate meal (HFCM) is a risk factor for cardiovascular disease (CVD). Numerous preclinical and clinical studies demonstrate anti-inflammatory

Effect of cumin powder on body composition and lipid profile in overweight and obese women.

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BACKGROUND This study aimed to determine the effect of cumin powder on body composition and lipid profile in overweight and obese women. METHODS In this randomized clinical trial, 88 overweight/obese women were randomly assigned into two groups. The experimental group was asked to have 3 g/d cumin

Ameliorating effects of fennel and cumin extracts on sperm quality and spermatogenic cells apoptosis by inducing weight loss and reducing leptin concentration in diet-induced obese rats.

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This study was established a model of obesity to estimate the impact of fennel and cumin as anti-obesity extracts on body weight, body mass index (BMI), food consumption, leptin concentration, sperm quality and testis architecture to determine the reversibility of reproductive function of obese

Effect of the cumin cyminum L. Intake on Weight Loss, Metabolic Profiles and Biomarkers of Oxidative Stress in Overweight Subjects: A Randomized Double-Blind Placebo-Controlled Clinical Trial.

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BACKGROUND The current study was performed to determine the effects of cumin cyminum L. intake on weight loss and metabolic profiles among overweight subjects. METHODS This randomized double-blind placebo-controlled clinical trial was conducted among 78 overweight subjects (male, n = 18; female, n =

The Effect of Cumin cyminum L. Plus Lime Administration on Weight Loss and Metabolic Status in Overweight Subjects: A Randomized Double-Blind Placebo-Controlled Clinical Trial.

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BACKGROUND Limited data are available regarding the effects of combined administration of Cumin cyminum L. and lime on weight loss and metabolic profiles among subjects with overweight subjects. OBJECTIVE The current study aimed to assess the effects of combined administration of Cumin cyminum L.

Effect of Carnitine and herbal mixture extract on obesity induced by high fat diet in rats.

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BACKGROUND Obesity-associated type 2 diabetes is rapidly increasing throughout the world. It is generally recognized that natural products with a long history of safety can modulate obesity. OBJECTIVE To investigate the development of obesity in response to a high fat diet (HFD) and to estimate the

Anti-Obesity Effect of Arq Zeera and Its Main Components Thymol and Cuminaldehyde in High Fat Diet Induced Obese Rats.

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Arq zeera is a distillate product that prepared from four different herbs namely Trachyspermum ammi L., apiaceae, Zingiber officinale Roxb., zingiberaceae, Carum carvi L.,apiaceae and Cuminum cyminum L., apiaceae. The present study aims to determine the antiobesity effect of arq zeera and its main

Heat stability of the in vitro inhibitory effect of spices on lipase, amylase, and glucosidase enzymes.

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This study investigated the effect of boiling on the inhibitory action of spices on digestive enzymes. Unboiled extracts of Trigonella foenum-graecum (seed) (25.42%), Myristica fragrans (seed) (22.70%), and Cuminum cyminum (seed) (19.17%) showed significantly (p

Safety assessment of black cumin fixed and essential oil in normal Sprague Dawley rats: Serological and hematological indices.
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Black cumin (Nigella sativa L.) is unique in its nutritional profile and it's fixed and essential oils are phytochemicals rich fractions. However, safety assessment is required before recommending their use. This study was designed to evaluate the safety of black cumin fixed oil (BCFO) and black

Effects of a novel formulation of essential oils on glucose-insulin metabolism in diabetic and hypertensive rats: a pilot study.
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BACKGROUND Insulin resistance and its most severe form type 2 diabetes mellitus are rapidly increasing throughout the world. It is generally recognized that natural products with a long history of safety can increase insulin sensitivity. OBJECTIVE The present investigation examined the ability of

Hypoglycaemic activity of two spices extracts: Rhus coriaria L. and Bunium persicum Boiss.
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The hypoglycaemic efficacy of sumac (Rhus coriaria L.) and black cumin (Bunium persicum Boiss) extracts were investigated through inhibition of a glycoside hydrolase: alpha-amylase. On the basis of our result ethyl acetate extract of sumac may have interest in the treatment and prevention of

Weight loss in animals and humans treated with "weighlevel", a combination of four medicinal plants used in traditional arabic and islamic medicine.
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Weighlevel, a mixture of extract of four plants used in traditional Arabic and Islamic medicine as well as in European herbal medicine, was prepared and assessed for its safety and efficacy in weight loss. Leaves of Alchemilla vulgaris, Olea europaea and Mentha longifolia L., as well as seeds of

Effects of Nigella sativa supplementation on blood parameters and anthropometric indices in adults: A systematic review on clinical trials.
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BACKGROUND Nigella sativa (N. sativa) has been used in traditional medicine and several studies have been performed in the last decades to reveal the effects of it on different medical disorders such as diabetes, dyslipidemia, hypertension, and obesity. We evaluated the effects of N. sativa

Spices in the management of diabetes mellitus.
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Diabetes mellitus (DM) remains a major health care problem worldwide both in developing and developed countries. Many factors, including age, obesity, sex, and diet, are involved in the etiology of DM. Nowadays, drug and dietetic therapies are the two major approaches used for prevention and control

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