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Letter: Levodopa and L-arginine to test GH release in obesity.

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Letter: Levodopa as a treatment of obesity.

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[Effect of long-term fasting on the blood serum insulin and growth hormone levels after loading tests with glucose, levodopa and exertion in obese patients with mormal and abnormal carbohydrate tolerance].

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Pre-operative obesity may influence subthalamic stimulation outcome in Parkinson's disease.

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BACKGROUND Pre-operative predictive factors for optimal post-operative effect of subthalamic nucleus (STN) stimulation in Parkinson's disease (PD) have been previously reported. No study has explicitly assessed the link between excess pre-operative body weight and STN stimulation outcome. METHODS We

An interaction between levodopa and enteral nutrition resulting in neuroleptic malignant-like syndrome and prolonged ICU stay.

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OBJECTIVE To describe a probable interaction between enteral feeds and levodopa leading to neuroleptic malignant-like syndrome (NMLS) in a polytrauma patient with Parkinson's disease (PD). METHODS A 63-year-old morbidly obese male polytrauma patient with PD and type 2 diabetes mellitus was admitted

The sleeve gastrectomy intervention to treat morbid obesity in a Parkinson's disease patient.

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OBJECTIVE Some Parkinson's disease patients may develop morbid obesity, on account of the reduction in exercise and/or of the appearance of compulsive food intake in the first years after diagnosis. The prescription of central appetite suppressants is actually not recommended in Parkinson's disease

The effect of levodopa with carbidopa (Sinemet R) on the metabolic response to semistarvation.

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It has been reported that levodopa will prevent the adaptive fall in the resting metabolic rate (RMR) on a weight-reducing diet. Whether levodopa has a central or peripheral effect on the RMR has been investigated by giving carbidopa, a peripheral dopa decorboxylase inhibitor with levodopa (as

Reduced Growth Hormone Secretion is Associated with Nonalcoholic Fatty Liver Disease in Obese Children.

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The purpose of the study was to evaluate the relationship between arginine-levodopa-induced growth hormone (GH) secretion and nonalcoholic fatty liver disease (NAFLD) in obese children. This study includes a total of 84 obese and 43 normal weight children. The obese subjects are divided into two

Effect of catecholamine replacement with levodopa on the metabolic response to semistarvation.

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The resting metabolic rate (R.M.R.) falls on energy restriction in association with a fall in the circulating calorigenic hormones, triiodothyronine (T3) and noradrenaline. Levodopa, a precursor of catecholamines, was given to obese subjects receiving a low-energy diet in an attempt to prevent the

Reduced peak stimulated growth hormone is associated with hyperuricemia in obese children and adolescents.

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The purpose of the study is to investigate whether reduced peak GH response to arginine-levodopa test is associated with hyperuricemia in obese children and adolescents. The study population consisted of a total sample of 78 obese and 30 normal-weight children and adolescents without known

Modulation of nutritional state in Parkinsonian patients with bilateral subthalamic nucleus stimulation.

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Chronic bilateral subthalamic stimulation (DBS-STN) provides considerable clinical benefits in Parkinson disease patients, with improvement in primary symptoms and resolution of side effects of chronic pharmacological treatment. Apart from its therapeutic effects on PD symptoms, DBS-STN also appears

Vascular risk factors and depression in Parkinson's disease.

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The aim of this study was to address the vascular depression hypothesis in Parkinson's disease (PD) from a large cohort of Chinese population. A cross-sectional analysis of 1784 Chinese patients with PD was conducted. Patients were divided into absence of depression (score ≤ 20) and presence of

Hypothalamic atrophy.

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A patient, who has been followed for thirteen years, developed the first symptoms of progressive hypothalamic atrophy at the age of 39. The diagnosis was confirmed by pneumoencephalography five years after onset. Hypothalamic dysfunction was manifested clinically by loss of libido, impotence,

Orexigenic effects of omentin-1 related to decreased CART and CRH gene expression and increased norepinephrine synthesis and release in the hypothalamus.

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Omentin-1, a visceral fat depot-specific secretory protein, is inversely correlated with obesity and insulin resistance. We investigated, in rats, the effects of chronic omentin-1 administration (8 μg/kg, intraperitoneally, once daily for 14-days) on feeding behavior and related hypothalamic

Shedding light on thyroid hormone disorders and Parkinson disease pathology: mechanisms and risk factors

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Parkinson's disease (PD) is a neurodegenerative disorder characterized by loss of dopaminergic neurons. Dopaminergic system is interconnected with the hypothalamic-pituitary-thyroid axis. Dopamine (DA) upregulates thyrotropin releasing hormone (TRH) while downregulating thyroid stimulating hormone

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