hypoxia/febră

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Hyperthermia and hypoxia increase tolerance of retinal ganglion cells to anoxia and excitotoxicity.

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OBJECTIVE Knowledge of the mechanisms by which retinal ganglion cells are damaged may provide information required to develop novel treatments for diseases that cause retinal ganglion cell death. The authors investigated whether the expression of the 72-kDa heat shock protein in cultured rat retinal

Progressive hypoxemia, hypercarbia and hyperthermia associated with prolonged anesthesia--a case report.

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The authors report a case of 66-year-old female patient, 55 kg, ASA I who, under general anesthesia in supine position, developed gradual hypoxemia (from a baseline PaO2 of 250 to 91 mmHg), carbon dioxide build up (from a baseline PaCO2 31 to 41 mmHg) associated with gradual hyperthermia up to 38.3

[Effect of exposure to physical loading, hypoxia and hyperthermia on factors of the cellular anti-infection protection of the body].

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Examinations of 146 healthy males aged 20-25 years have shown that moderate exercise stimulates the function of peripheral macrophages. The same effect is produced by exercise in combination with a single exposure to hypoxia. On the contrary, combined exposure to exercise, hypoxia and hyperthermia

[The role of oxygen-binding properties of hemoglobin in the development of oxygen deficiency in acute exogenous hyperthermia].

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Acid-base balance and oxygen-binding hemoglobin properties in mixed venous blood have been studied in 25 mongrel rabbits with acute environmental hyperthermia. As oxygen-hemoglobin affinity at standard pH, pCO2 and temperature increases, the effect of heat on oxygen-hemoglobin interaction is

Hyperthermia inhibits hypoxia-induced epithelial-mesenchymal transition in HepG2 hepatocellular carcinoma cells.

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OBJECTIVE To investigate the effect of hyperthermia on hypoxia-induced epithelial-mesenchymal transition (EMT) in HepG2 hepatocellular carcinoma (HCC) cells, and its mechanism. METHODS Cells were treated with hyperthermia at 43 °C for 0.5 h, followed by incubation under hypoxic or normoxic

[A comparative evaluation of the efficacy of pharmacotherapeutic agents in hypoxia in the presence of hyperthermia].

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In conditions of acute hypoxia in the presence of hyperthermia drugs were shown to exhibit various degrees of protective activity. Antihypoxic action coupled with thermoprotective activity is manifested by beneficial affect on the course of the pathological process. It is quercitrol that proved to

Preferential topography of proteins regulating vascularization and apoptosis in a MX1 xenotransplant after treatment with hypoxia, hyperthermia, ifosfamide, and irradiation.

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The MX1 xenotransplant growing in nude mice was used as a model for estrogen- and progesterone-receptor-negative breast cancer. The effects of different therapeutic regimens-combinations of hyperthermia, chemotherapy, and irradiation-on the expression of proteins playing a role in tumor

Postischemic hyperthermia induced caspase-3 activation in the newborn rat brain after hypoxia-ischemia and exacerbated the brain damage.

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The effects of postischemic hyperthermia were investigated in the newborn rat brain after hypoxia-ischemia (HI). Seven-day-old rats were subjected to left carotid artery ligation followed by 8% oxygen for 30 min, and divided into a hyperthermia group (rectal temperature at 39 degrees C for 6 h) and

Does acute hypoxemia blunt sympathetic activity in hyperthermia?

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Sympathetic alpha-adrenergic function is depressed by hypoxemia per se; does addition of another sympathoexcitatory stimulus elicit normal responses in other sympathetic effector pathways? We activated by hyperthermia four sympathetic pathways: alpha-adrenergic [norepinephrine (NE) release],

Influence of hypoxia and hyperthermia upon peroxidative and glutathione status in growth-restricted newborn piglets.

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Normal weight (NW) and spontaneously intra-uterine growth-restricted newborn piglets (IUGR) were submitted to 1 hour hypoxia and hyperthermia followed by 3 hours reoxygenation. Glutathione (GSH, GSSG), lipid peroxidation products (TBAR) and cytochrome P450 dependent production of reactive oxygen

[The effect of quercetin on the metabolic processes in combined body exposure to hypoxia and hyperthermia].

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Quercetin given in a dose of 100 mg/kg 3 hours before acute systemic hypoxia (10 ob%) combined with hyperthermia (43 degrees C) has been demonstrated to prevent a drastic activation of lipid peroxidation and arachidonic acid metabolism parallel to a marked decrease the activity of the body's

Effect of hyperthermia and anoxia on glucocorticoid and mineralocorticoid receptor expression in neonatal rat hippocampus.

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Brief periods of neonatal asphyxia are frequently observed. Within the CNS, the hippocampus is known to be particularly vulnerable to the damaging effects of hypoxia/ischaemia. The hippocampus contains the highest concentration of both mineralocorticoid (MR) and glucocorticoid (GR) receptors and the

Effects of hypothermia and hyperthermia on attentional and spatial learning deficits following neonatal hypoxia-ischemic insult in rats.

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We previously reported that rats exposed to neonatal hypoxic-ischemic (HI) insult showed selective and long-lasting learning and memory impairments in the plus maze, 8-arm radial maze, choice reaction time (CRT) task, and water maze, and that they showed severe brain injury to areas such as parietal

Interleukin-1beta-induced fever does not alter the ability of 5- to 6-day-old rat pups to autoresuscitate from hypoxia-induced apnoea.

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Experiments were carried out to determine if endogenous pyrogen-induced fever impairs protective responses of newborn rats to hypoxia. Twenty-seven 5- to 6-day-old conscious rat pups received a subcutaneous injection of 0.20 microg of recombinant rat interleukin-1beta (rrIL-1beta) per kilogram of

Influence of passive hyperthermia on human ventilation during rest and isocapnic hypoxia.

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The purpose of this study was to examine the potential interaction of core temperature and isocapnic hypoxia on human ventilation and heart rate (HR). In 2 resting head-out water-immersion trials, 8 males first breathed air and then 12% O2 in N2 while the end-tidal partial pressure of carbon dioxide

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