kidney neoplasms/cefalee

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From headache to kidney tumor; an example of von Hippel- Lindau disease.

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BACKGROUND von Hippel-Lindau disease (VHL) is a rare genetic condition caused by the mutation of the VHL tumor suppressor gene and predisposing to various benign or malignant tumors involving mainly central nervous system (CNS) and retinal hemangioblastomas (RHB). Although considered as occult,

Headache in cerebral venous thrombosis associated with extracranial tumors: a clinical series.

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Cerebral venous thrombosis (CVT) may represent the clinical onset of malignancies or complicate their course, also in phase of quiescence. In literature, there are several case reports on the association between CVT and tumors, but there are few articles on its clinical characteristics in cancer

An indirect comparison of the toxicity of sunitinib and pazopanib in metastatic clear cell renal cancer.

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BACKGROUND Both sunitinib and pazopanib are widely used as first line therapy in metastatic renal cancer (mRCC). The efficacy of these agents appears similar but they may have distinct toxicity profiles. In this study we compare the severity of symptomatic and asymptomatic toxicity associated with

Solved and unsolved headache problems.

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Two unusual cases of vascular headache, one caused by jugular venous compression from a goiter and one triggered by flushing associated with a CGRP-producing renal tumour, are reported. Their histories are compared with those experiencing other headaches of vascular origin. Two patients with a

[Renin-secreting renal tumor. A case report].

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We reported a case of juxtaglomerular cell tumor, which excessively produced renin, resulting in secondary hypertension. A 25-year-old woman complained of headache and nausea. Hypertension and elevation of plasma renin activity were found by physical and laboratory examination. US and CT showed a

[Meningitis and renal cancer].

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A 51 year-old man with a renal cancer (pT3N0M0) consulted at the emergency department for persistent headache initiated a week before and recent vomiting. Physical examination and blood analyses were not remarkable. Cerebral magnetic resonance imaging demonstrated radiological signs of meningitis.

A multicentre phase II trial of bryostatin-1 in patients with advanced renal cancer.

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Protein kinase C (PKC) has a critical role in several signal transduction pathways, and is involved in renal cancer pathogenesis. Bryostatin-1 modulates PKC activity and has antitumour effects in preclinical studies. We conducted a multicentre phase II clinical trial in patients with advanced renal

Intracranial tuberculoma mimicking metastasis from renal tumor--case report.

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A 63-year-old female presented with intracranial tuberculoma manifesting as severe headache. Systemic examination found a mass in the left kidney. The histological diagnosis was tuberculoma after kidney biopsy. Cranial computed tomography found two lesions, in the right frontal and occipital lobes.

Granulomatosis with polyangiitis presenting as a renal tumor.

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Inflammatory tumors of the kidney are uncommon and include primary inflammatory processes and systemic diseases such as sarcoidosis, IgG4 disease, and granulomatosis with polyangiitis (GPA). There are approximately 15 cases of the latter in the literature. Tumors in GPA are well described and have

[Treatment of advanced kidney cancer using recombinant erythropoietin].

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OBJECTIVE Study of the antitumour effects of erythropoietin on metastatic renal cell carcinoma. METHODS After giving their informed consent, 20 patients with histologically proven metastatic renal cell carcinoma received subcutaneous recombinant erythropoietin three times a day at a dose of 150

Rare metastasis of renal carcinoma in the frontoethmoid-orbital region - case report and review of the literature.

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A tumor located in the region of the paranasal sinuses and the orbit is not usually a metastasis, but a primary tumor. Even more, renal cell carcinoma (RCC) is very rarely the cause of metastasis in the paranasal sinuses or the orbit. Up to the present moment, few cases have been reported in the

[A case of malignant paraganglioma presenting with skull metastases].

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A non-functioning paraganglioma is usually benign, however, it may cause distant metastases. There is no histological appearance for the diagnosis of malignancy or absolute criteria for predicting malignant potential. Bony metastases from paraganglioma are known to occur, but, skull metastases are

Phase II trial of interleukin 2, interferon alpha, and 5-fluorouracil in metastatic renal cell cancer: a cytokine working group study.

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The purpose of this study was to evaluate the potential efficacy of alternating two outpatient regimens for the treatment of metastatic renal cell cancer. These regimens consisted of 4 weeks of recombinant interleukin 2 (rIL-2) plus IFN-alpha2B followed by 4 weeks of 5-fluorouracil plus IFN-alpha2B.

Clear cell sarcoma of the kidney distinguished from synovial sarcoma using genetic analysis: a case report.

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BACKGROUND The most common pediatric renal neoplasm is Wilms tumor, but clear cell sarcoma of the kidney or synovial sarcoma of the kidney are also sometimes encountered. Accurate pathological diagnosis is important, because adjuvant therapies including chemotherapy and radiotherapy differ according

Birt-Hogg-Dubé syndrome caused by a mutation of FLCN gene in a CVST patient: A case report.

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To our knowledge, this is the first report of patient with BHD syndrome caused by a novel mutation in the FLCN gene who developed a cerebral venous sinus thrombosis(CVST).A 62-year-old male patient with a history of hypertension and two case of spontaneous

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