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Medullary carcinoma of the thyroid in the multiple mucosal neuromas syndrome.

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The clinical features of the multiple mucosal neuromas (MMN) syndrome permit the recognition of these patients and their potential development of the associated medullary thyroid carcinoma (MTC). The distinctive physical appearance caused by the mucosal neuromas, the Marfanoid habitus and,

Complications of the Middle Cranial Fossa Approach for Acoustic Neuroma Removal.

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OBJECTIVE To analyze postoperative complications after microsurgery for acoustic neuroma (AN) via the middle fossa approach (MFA). METHODS In total, 203 consecutive patients of a tertiary skull base referral center at a university hospital were included in this retrospective chart and database

[Clinical manifestations, therapeutic response to tyrosinase inhibitor and RET gene activating mutation in a patient with multiple endocrine neoplasia 2B].

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OBJECTIVE To explore the clinical manifestations, therapeutic response and RET gene mutation in a patient with multiple endocrine neoplasia 2B (MEN2B) characterized by medullary thyroid carcinoma (MTC), bilateral adrenal pheochromocytoma and multiple mucosal neuromas. METHODS The clinical features,

Rare syndromes.

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Dermatologists may also encounter patients presenting with skin lesions that reflect an underlying endocrine disorder not commonly seen in daily practice. Some of these endocrine disorders include glucagonoma, neurofibromatosis type 1, McCune-Albright syndrome, multiple endocrine neoplasia, the

Medullary carcinoma of the thyroid.

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Medullary carcinoma is an unusual malignant neoplasm. The cell of origin is considered to be the C-cell which is derived from the ultimobranchial body and neural crest. The tumor is solid and has characteristic amyloid in the stroma. The lesion usually presents as a neck mass, and multicentricity is

[Medullary carcinoma of the thyroid (author's transl)].

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Medullary carcinoma of the thyroid develops in the parafollicular C cells, the origin of which is in the neural crest. It is characterized clinically by the presence of motor diarrhea, vasomotor attacks, and immunologically by the presence of an amyloid stroma and the appearance of an anaplastic

The empty sella.

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OBJECTIVE To discuss the diagnostic imaging findings of an empty sella in a chiropractic patient with emphasis on magnetic resonance imaging (MRI) of normal and abnormal pituitary appearances. METHODS A 44-year-old woman started having headache, dizziness, nausea, vomiting, and diarrhea after an

The Reality of Multiple Endocrine Neoplasia Type 2B Diagnosis: Awareness of Unique Physical Appearance Is Important.

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BACKGROUND Multiple endocrine neoplasia type 2B (MEN2B) is an extremely rare syndrome mainly caused by RET918 germline mutations. MEN2B typically causes medullary thyroid carcinoma (MTC), pheochromocytoma, and unique physical characteristics including mucosal neuroma, distinctive facial appearance,

[Neurogenic appendicopathy -- a common disorder, seldom diagnosed (author's transl)].

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Over 5000 routine appendix specimens were examined at the Institute for Pathological Anatomy, Graz University, for the presence of neurogenic appendicopathy (n.a.). With light microscopy it was possible to differentiate intramucosal, finely vacuolated nerve proliferations and central neuromas (n.a.

Gastrointestinal manifestations of multiple endocrine neoplasia type 2.

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OBJECTIVE To determine the clinical features, natural history, and role of surgery for gastrointestinal manifestations of the multiple endocrine neoplasia type 2 (MEN 2) syndromes. BACKGROUND The MEN 2 syndromes are characterized by medullary thyroid carcinoma and other endocrinopathies. In

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