nicotinic acid/accident vascular cerebral

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[Research on the action of vasoactive drugs on cerebral circulation in patients suffering from apoplectic strokes. II. Action of nicotinic acid].

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[Treatment of patients having suffered ischemic stroke with nicotinic acid and antichoagulants].

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[Administration of nicotinic acid in cerebral circulatory disorders, especially in states following apoplexy with hemiplegia].

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Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes with acanthocytosis: a clinicopathological study of a unique case.

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A case of a unique combination of mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like syndrome (MELAS) with acanthocytosis is reported. Neuropathological examination revealed pellagra-like change in Betz cells, brain-stem neurons and anterior horn cells as well as findings

Meta-analysis of the effect of nicotinic acid alone or in combination on cardiovascular events and atherosclerosis.

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OBJECTIVE High-density lipoprotein cholesterol (HDL-C) concentration is a strong predictor of cardiovascular events in both naïve and statin-treated patients. Nicotinic acid is an attractive option for decreasing residual risk in statin-treated or statin-intolerant patients since it increases HDL-C

Elevated serum lipoprotein(a) as a risk factor for combined intracranial and extracranial artery stenosis in a child with arterial ischemic stroke: A case report.

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BACKGROUND Stroke is an uncommon disease in childhood with an estimated incidence of 1 to 6 per 100,000 and stenoocclusive arteriopathy is the main risk factor of recurrent pediatric arterial ischemic stroke (AIS). Dyslipidemia may influence strongly before puberty and in late adolescence when

Transient receptor potential melastatin subfamily member 2 cation channel regulates detrimental immune cell invasion in ischemic stroke.

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OBJECTIVE Brain injury during stroke results in oxidative stress and the release of factors that include extracellular Ca(2+), hydrogen peroxide, adenosine diphosphate ribose, and nicotinic acid adenine dinucleotide phosphate. These alterations of the extracellular milieu change the activity of

Hemodynamic effects of nicotinic acid infusion in normotensive and hypertensive subjects.

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Nicotonic acid (NA) infusions are associated with peripheral vasodilation from the generation of vascular prostaglandins with minimal effects on blood pressure (BP) in normotensive subjects. We studied the effects of a NA infusion in 10 hypertensive and 11 normotensive individuals to further

SIRT1 and stem cells: In the forefront with cardiovascular disease, neurodegeneration and cancer.

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Cardiovascular disease, nervous system disorders, and cancer in association with other diseases such as diabetes mellitus result in greater than sixty percent of the global annual deaths. These noncommunicable diseases also affect at least one-third of the population in low and middle-income

Drug interactions of lipid-altering drugs.

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The use of lipid-altering drugs has been shown to reduce the progression of atherosclerotic lesions and reduce the risk of atherosclerotic events (such as myocardial infarction and stroke). In general, these lipid-altering drugs are well tolerated but there is the potential for drug interactions.

Primary prevention of CVD: treating dyslipidaemia.

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BACKGROUND The incidence of dyslipidaemia is high: in 2000, approximately 25% of adults in the USA had total cholesterol greater than 6.2 mmol/L or were taking lipid-lowering medication. Primary prevention in this context is defined as long-term management of people at increased risk but with no

Dietary markers of hypertension associated with pulse pressure and arterial compliance in black South African children: the THUSA Bana Study.

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OBJECTIVE The aim of the study was to determine which dietary factors contribute to the impairment of arterial compliance, stroke volume, total peripheral resistance and pulse pressure, and could thereby be identified as risk markers in the development of hypertension in black

Treatment of common lipoprotein disorders.

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The pathogenesis of arteriosclerosis is not yet fully understood. The growing body of scientific information strongly indicates that the plasma lipoproteins are playing a crucial role in the development of this disease. We now have conclusive information that dietary cholesterol can produce

[Hypolipidemic drugs and diabetes mellitus].

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Diabetes mellitus associates with high cardiovascular risk. The absolute values of cardiovascular risk tend to be even higher than as calculated from the SCORE tables. Recent randomized clinical trials have shown evidence of benefit and safety of more intensive LDL-cholesterol lowering in patients

Lipid lowering in diabetes mellitus.

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OBJECTIVE The purpose of this review is to present recent information on lipid lowering in diabetes mellitus. New information from randomized clinical trials will be discussed together with implications for clinical practice. Residual risk persists despite statin therapy and additional approaches,

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