physostigmine/febră

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Morphine hyperthermia in the rat: its attenuation by physostigmine.

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1. In rats, a subcutaneous injection of morphine (2.5 mg/kg) produced hyperthermia which was greatly attenuated by an intraperitoneal injection of physostigmine (0.1 mg/kg), but not of neostigmine (0.08 mg/kg) and promptly reversed by a subcutaneous injection of nalorphine.2. It is concluded that

[Studies on so-called central and peripheral fevers. Studies on the effect of physostigmine, largactil and reserpine].

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[Effect on the so-called central and peripheral fever. Studies on the effect of physostigmine, largactil and reserpine].

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Physostigmine attenuation of delta 9-tetrahydrocannabinol induced hyperthermia in rats.

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[Poisoning with Jimson weed. Five cases treated with physostigmine].

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During the autumn of 1995, the National Poisons Information Centre was contacted about several cases of poisoning with Jimson weed (Datura stramonium). Five cases are described here. Upon admission to hospital the patients had moderate to severe anticholinergic symptoms, such as mydriasis, sinus

[Fever, large eyes and confusion; the anticholinergic syndrome].

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A 52-year-old woman was in a confused state and had difficulty walking and swallowing, as well as dysarthria. That same day she had consumed some berries, which she thought were bilberries, but she had instead eaten Atropa belladonna (deadly nightshade). She made a spontaneous and full recovery

Massive atropine eye drop ingestion treated with high-dose physostigmine to avoid intubation.

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METHODS A 34-year-old male presented after ingesting 150 mg of atropine. He had altered mental status, sinus tachycardia, dry mucosa, flushed skin, and hyperthermia. Sequential doses of physostigmine, totaling 14 mg, were successful in reversing antimuscarinic toxicity and prevented the need to

[A case of malignant neuroleptic syndrome with rhabdomyolysis and a therapeutic trial using physostigmine].

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We report the case of a 22-year-old schizophrenic patient who developed a neuroleptic malignant syndrome under treatment with Benperidol, Levomepromazin and Biperiden. Clinical signs were: fever, rigidity, altered consciousness and rhabdomyolysis of hip-abductors. Intravenous injection of

Use of a physostigmine continuous infusion for the treatment of severe and recurrent antimuscarinic toxicity in a mixed drug overdose.

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BACKGROUND Physostigmine was once a widely used antidote for the treatment of antimuscarinic toxicity. However, reports describing the association of physostigmine with asystole and seizures in severe tricyclic antidepressant poisoning resulted in a decrease in use. Recent literature has

Dissimilar effects on body temperature in the cat produced by guanosine 3',5'-monophosphate, acetylcholine and bacterial endotoxin.

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1 Guanosine 3',5'-monophosphate (cyclic GMP) and N2-2'-O-dibutyryl guanosine 3',5'-monophosphate (db cyclic GMP) have been injected into the third cerebral ventricle (i.c.v.) of the unanaesthetized cat and the effects of rectal temperature and on behavioural and autonomic activities observed and

[Central anticholinergic syndrome during postoperative period].

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The central anticholinergic syndrome (CAS) includes central signs (somnolence, confusion, amnesia, agitation, hallucinations, dysarthria, ataxia, delirium, stupor, coma) and peripheral signs (dry mouth, dry skin, tachycardia, visual disturbances and difficulty in micturition). It occurs when central

Does GABA act through dopaminergic/cholinergic interaction in the regulation of higher environmental temperature-induced change in body temperature?

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Acute exposure of adult male albino rats to higher ambient temperature (40 degrees C) for 2 h significantly increased body temperature (BT). Administration of either bicuculline (1 mg/kg, i.p.), a GABA antagonist, or physostigmine (0.1 mg/kg, i.p.), an inhibitor of acetylcholinesterase,

Cholinomimetic activity of minaprine is related to the amelioration of delayed neuronal death in gerbils.

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We attempted to determine if the cholinomimetic activity of the psychotropic drug minaprine was related to the amelioration of the delayed neuronal death induced by cerebral ischemia in Mongolian gerbils. Minaprine improved the passive avoidance deficit induced by cerebral ischemia, and the

Thermic response of selective muscarinic agonists and antagonists in rat.

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Effect of some selective agonists and antagonists of cholinergic M receptor subtypes on rectal temperature was investigated in rats at an ambient temperature of 25 degrees +/- 2 degrees C. Centrally administered acetylcholine (ACh) induced transient hypothermia, whereas the muscarinic M1 receptor

Higher environmental temperature-induced increase of body temperature: involvement of central opioidergic-GABAergic interaction.

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Exposure (2 h) of male albino rats to higher environmental temperature (HET, 40 degrees C) significantly increased the body temperature (BT). Administration of bicuculline (1 mg/kg, i.p.), physostigmine (0.2 mg/kg, i.p.), or their combination significantly raised the BT of normal rats (kept at 28

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