polycythemia/cefalee

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[Headache caused by polycythemia vera. Classification of a headache under the heading of metabolic disturbances].

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As polycythemia vera is a myeloproliferative syndrome, it is based on an autonomic increase in the proliferation of all hematopoetic cells--mostly of erythropoesis. An increase in blood viscosity induces disturbed microcirculation, resulting in headaches with clinical symptoms. So far, the headache

Cluster-Like Headache Revealing Polycythemia Vera: A Case Report

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Herein, we report on a 44-year-old man who presented with cluster headache (CH)-like pain triggered by polycythemia vera (PV). He had severe unilateral head pain attacks lasting about 30 min not associated with cranial autonomic symptoms. After the exclusion of secondary etiologies, the patient was

Sudden onset of severe headache associated with polycythemia: hyperdense middle cerebral arteries demonstrated by cranial computed tomography.

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Associations of high-altitude polycythemia with polymorphisms in PIK3CD and COL4A3 in Tibetan populations.

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High-altitude polycythemia (HAPC) is a chronic high-altitude disease that can lead to an increase in the production of red blood cells in the people who live in the plateau, a hypoxia environment, for a long time. The most frequent symptoms of HAPC include headache, dizziness, breathlessness, sleep

Erythrocytosis in a scleroderma patient.

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A 40-year-old black male with scleroderma lung disease presented with blurry vision and headache. His presenting hemoglobin was 22.3 g/dL and his serum erythropoietin level was surprisingly low. Although nocturnal hypoxemia was evident, his daytime resting arterial oxygen saturation was normal. The

Safety and efficacy findings from the open-label, multicenter, phase 3b, expanded treatment protocol study of ruxolitinib for treatment of patients with polycythemia vera who are resistant/intolerant to hydroxyurea and for whom no alternative treatments are available.

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Ruxolitinib was recently approved for the treatment of patients with polycythemia vera who are resistant/intolerant to hydroxyurea based on data from the RESPONSE studies. This phase 3b, Expanded Treatment Protocol study (NCT02292446) of ruxolitinib for hydroxyurea-resistant/intolerant patients with

Recurrent cerebral venous sinus thrombosis in a young man- A case report of JAK2-negative polycythemia vera.

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Polycythemia vera (PV) is a myeloproliferative disorder most commonly associated with JAK2V617F mutation. Cerebral venous sinus thrombosis (CVST) has a wide range of etiologies and PV is one of them. CVST associated with PV has a poor prognosis. Some patients with classical PV lack

Neurologic complications of polycythemia and their impact on therapy.

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Polycythemia vera, a clonal stem cell disorder, produces neurologic problems in 50-80% of patients. Some symptoms, such as headache and dizziness, are related to hyperviscosity, and respond immediately to reduction of cell counts. Others seem to result from an associated coagulopathy. Patients with

Polycythemia vera presenting with bilateral papilledema: a rare case report.

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A 45-year-old male patient presented with gradual onset of headache, vomiting and blurring of vision of 28 days duration. Ophthalmological examination revealed normal anterior segment and pupillary reflex. No abnormality was detected in the vitreous. Optic disc showed features of advanced

Rheological study on vascular occlusion and cellular hyperviscosity syndrome in polycythemia vera.

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Whole blood viscosity was determined in 10 patients with polycythemia vera and 129 normal controls using a cone-plate type rotational viscometer at 37 degrees C. Three of the patients with polycythemia vera exhibited vascular occlusions including cerebral and myocardial infarction. The remaining

Migraine attacks, aura, and polycythemia: a vasculoneural pathogenesis?

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Headache is a frequent symptom of polycythemia. A case study of a polycythemia vera patient affected by migraines, with and without aura, who developed headache attacks with aura in association with elevated haematocrit and haemoglobin levels is presented. A vasculoneural pathogenesis is supposed.

Cerebral arteriovenous malformation presenting with polycythemia vera: A case report and literature review.

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BACKGROUND Cerebral arteriovenous malformations (AVM) usually present with headache, hemorrhage, or seizure. Erythropoietin (EPO) has demonstrated protective effects against ischemia within the CNS. METHODS The authors report a patient with a cerebral AVM and concurrent polycythemia associated with

[Polycythemia vera: clinical aspects and course in 86 patients].

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We analyze symptoms, clinical course, and survival time of 86 patients with polycythemia vera treated between 1966 and 1987 at the medical polyclinic of the University Hospital of Zürich. The mean age of disease onset in 40 men and 46 women studied was 59 years. Most commonly the first symptoms were

Right Hand Weakness and Headache During Ascent to Mount Everest: A Case of Cerebral Venous Infarction.

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BACKGROUND The increasing popularity of trekking in alpine regions has drawn attention to high altitude-associated health concerns. METHODS Here, we report a case of cerebral venous infarction as a consequence of a hypercoagulable state induced by secondary polycythemia as an adaptation to high

Cerebral Venous Thrombosis and Venous Infarction: Case Report of a Rare Initial Presentation of Smoker's Polycythemia.

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INTRODUCTION: Cerebral venous thrombosis is a rare initial presentation of polycythemia. If diagnosed early, treatment can reduce mortality and morbidity significantly. Often it may present with headache as the only complaint, and thus the diagnosis is likely to be missed. CASE PRESENTATION: A

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