primula rosea/hypersensitivity

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Primula obconica--is contact allergy on the decline?

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Primula obconica, a member of the Primulaceae family, was introduced to Britain from China in 1880. P. obconica cultivars, which are reputed to contain less primin, have been developed over the past number of years in an attempt to reduce the incidence of allergic contact dermatitis. Primin

Primula allergic dermatitis simulating occupational contact dermatitis induced by metals, oils and greases.

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A case of the hands and face dermatitis in a patient employed in a store with motor-car spare parts is presented. Both the patient and her doctor were convinced that skin lesions were caused by the contact with metals, oils and greases. After detecting allergy to primine (after 48 and 96 h, + +),

[Allergic contact dermatitis caused by garlic, Primula, Frullania and Compositae].

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As a complementary study to a previous work (14) in which we examined 43 cases of contact dermatitis to plants, we have taken a closer look at the provocative cases which made up 76% of that study - Allium (garlic) (11 cases), Primula (8), Frullania (8) and Compositae (6). The clinical methodology,

Structure-activity relationships in allergic contact dermatitis (I). Studies on the influence of side-chain length with derivatives of primin.

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Primin (2-methoxy-6-pentyl-1,4-benzoquinone) is a naturally-occurring strong sensitizer from Primula obconica (Primulacease). To determine the effect of side-chain length on sensitizing potency, 15 analogues with linear side chains from C1 to C15 and 4 C6-analogues with branched side chains were

Erythema multiforme-like eruption: an unusual presentation of primula contact allergy.

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Allergic contact dermatitis from primula presenting as vitiligo.

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Allergic contact dermatitis from Primula auricula and Primula denticulata.

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5,8-dihydroxyflavone (primetin) the contact sensitizer of Primula mistassinica Michaux.

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5,8-Dihydroxyflavone (primetin) has been shown to be the sensitizer in Primula mistassinica Michaux and probably the source of allergic contact dermatitis in four milkers. Its sensitizing properties as determined in guinea-pigs, are strong. As far as is known this is the first experimental

Routine testing for Primula obconica: is it useful in the United States?

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Allergic contact dermatitis to Primula obconica has long been established. It is considered a significant allergen in Europe and has been included in standard screening there. The allergen is much less common in the United States. The frequency of allergy to P obconica in the United States is

Primin in the European standard patch test series for 20 years.

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Primin was included in the European standard series (ESS) in 1984. In 2000, a primin-free variant of Primula obconica, the main source of contact allergy to primin, was introduced in the market. The aim of this study was to analyse the trends of primin allergy in 13 986 consecutively patch-tested

The sensitizing capacity of naturally occurring quinones. Experimental studies in guinea pigs. II. Benzoquinones.

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Experimental studies on the sensitizing capacity of naturally occurring benzoquinones, isolated from plants and woods have been carried out in guinea pigs of the Pirbright white strain. Seven compounds were available: primin, three dalbergiones, mansonia quinone (mansonone A),

Primin sensitization in north-eastern Italy: a temporal trend from 1996 to 2012.

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BACKGROUND Primin is the main contact allergen found in the ornamental plant Primula obconica Hance. OBJECTIVE To analyse the temporal trend of sensitivity to primin in north-eastern Italy and to evaluate the associations with occupations in our geographical area. METHODS From 1996 to 2012, 24 052

Primula dermatitis.

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We report the cases of 2 patients diagnosed as having primula dermatitis. Both patients were housewives who had been exposed to primula plants. Although only one related her clinical manifestations with looking after plants, the symptoms of both remitted when contact with primula was avoided. The

Contact dermatitis due to hardy Primula species and their cultivars.

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For more than 100 years, it has been widely held that of all the Primula species to cause allergic contact dermatitis, P. obconica is the most likely culprit, particularly in Northern Europe. The main sensitizer is primin, but other sensitizers are reported. Other species are rarely implicated, but

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