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Screening for antimycotic properties of 56 traditional Chinese drugs.

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In the present study we screened extracts of 56 widely used dried Chinese medical plants or their parts (TCD) for their antimycotic properties against pathological phyla of Aspergillus fumigatus, Candida albicans, Geotrichum candidum and Rhodotorula rubra. The highest activity against Aspergillus

[Therapeutic effects of Chinese drugs on early renal damage of rats caused by fish bile].

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The therapeutic effects of Salvia miltiorrhizae, Typha angustifolia, Rheum palmatum preparations on early renal damage of rats caused by fish bile were observed. These drugs were effective in reducing serum creatinine, urinary NAGase, count of necrosed epithelial cells of proximal tubule and that of

[Preventive and therapeutic effects of extract from Rheum palmatum on hepatic encephalopathy in rats with acute liver failure].

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OBJECTIVE To probe the preventive, therapeutic effect and the possible mechanism of extract from Rheum palmatum (ERP) on hepatic encephalopathy(HE) in rats with acute liver failure. METHODS HE was induced by the administration of 300 mg thioracetamide per kg body weight by gavage on two consecutive

[Evaluation of antifungal effects of a traditional medicine containing 17 components on Trichophyton verrucosum and Malassezia pachydermatis by microdilution].

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The minimum inhibitory concentration(MIC)of a traditional medicine containing 17 components against 9 strains of Trichophyton verrucosum and 13 strains of Malassezia pachydermatis was determined using a method recommended by the Clinical and Laboratory Standards Institute(CLSI). We also measured the

[Experimental studies of therapeutic effect of Rheum officinale on acute pancreatitis].

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OBJECTIVE To investigate the therapeutic effect of Rheum offĩcinale on acute pancreatitis. METHODS Buffered sodium taurocholate (3% m/V) was injected into the pancreatico-biliary duct to induce acute pancreatitis. Death rate,coefficient of pancreas, serum amylyse (AMY), hemocuprein (SOD), TNF-alpha

The pharmacology, toxicology and therapeutic potential of anthraquinone derivative emodin

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Emodin (1, 3, 8-trihydroxy-6-methylanthraquinone) is a derived anthraquinone compound extracted from roots and barks of pharmaceutical plants, including Rheum palmatum, Aloe vera, Giant knotweed, Polygonum multiflorum and Polygonum cuspidatum. The review aims to provide a scientific summary of

Antitumor and apoptosis-promoting properties of emodin, an anthraquinone derivative from Rheum officinale Baill, against pancreatic cancer in mice via inhibition of Akt activation.

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Pancreatic adenocarcinoma is one of the most common malignancies worldwide. Gemcitabine is currently the standard first-line chemotherapeutic agent for pancreatic cancer. However, gemcitabine can induce activation of Akt and nuclear factor-κB (NF-κB), which is associated with its chemoresistance. It

Emodin ameliorates cartilage degradation in osteoarthritis by inhibiting NF-κB and Wnt/β-catenin signaling in-vitro and in-vivo.

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The overproduction of MMPs (matrix metalloproteinases) and members of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family plays an important role in the pathogenesis of osteoarthritis (OA). The potential of selective MMPs or ADAMTS inhibitors as chemopreventive

Anti-fibrotic and anti-tumorigenic effects of rhein, a natural anthraquinone derivative, in mammalian stellate and carcinoma cells.

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Anthraquinone compounds have been recognized to possess antiinflammatory, anti-fibrotic and anti-tumour properties and thus applied in human and veterinary therapeutics as active substances of medicinal products. Amongst the anthraquinones isolated from Rheum palmatum, also known as da-huang, rhein

Antiinflammatory and Hepatoprotective Medicinal Herbs as Potential Substitutes for Bear Bile.

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Practitioners of traditional Chinese medicine (TCM) commonly prescribe medicinal formulations relying on the purported synergism of a combination of plant species, sometimes incorporating animal parts and minerals. Bear bile, obtained from either wild or farmed bears, is a commonly used constituent

Rheum australe, an endangered high-value medicinal herb of North Western Himalayas: a review of its botany, ethnomedical uses, phytochemistry and pharmacology.

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Rheum australe (Himalayan Rhubarb) is a multipurpose, endemic and endangered medicinal herb of North Western Himalayas. It finds extensive use as a medicinal herb since antiquity in different traditional systems of medicine to cure a wide range of ailments related to the circulatory,

Rheum australe D. Don: a review of its botany, ethnobotany, phytochemistry and pharmacology.

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BACKGROUND Rheum australe D. Don (Polygonaceae) has been commonly used in traditional medicine for a wide range of ailments related to the circulatory, digestive, endocrine, respiratory and skeletal systems as well as to infectious diseases. OBJECTIVE To provide the up-to-date information that is

Apoptosis induction in MDA-MB-435S, Hep3B and PC-3 cell lines by Rheum emodi rhizome extracts.

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The study was aimed at evaluating apoptosis induction potentials of methanolic and aqueous extracts of Rheum emodi Wall. ex Meissn. rhizome. The ability of the extracts to induce apoptosis in MDA-MB-435S (human breast carcinoma), Hep3B (human hepatocellular carcinoma) and PC-3 (human prostate

The natural anthraquinones from Rheum palmatum induced the metabolic disorder of melatonin by inhibiting human CYP and SULT enzymes.

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Melatonin (Mel) as an endogenous hormone, has been widely used in clinic for multiple therapeutic purposes. Further, the natural anthraquinones were widespread in various plants including herbs, foods, and some flavoring agents. The present work aims to evaluate the metabolic disorder of Mel caused

Antibacterial and antioxidant activities of traditional medicinal plants from the Erzurum region of Turkey.

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In this study, 13 different extracts were investigated which are grown in the region of Erzurum.The aim of this study was to screen various plant extracts that are known and used for medicinal purposes such as Ferula communis L., Rumex patientia L.,

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