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Antipyretic Effect of Herba Ephedrae-Ramulus Cinnamomi Herb Pair on Yeast-Induced Pyrexia Rats: A Metabolomics Study.

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OBJECTIVE To investigate the antipyretic mechanism of Herba Ephedrae (Eph)-Ramulus Cinnamomi (RC) herb pair on yeast-induced pyrexia in rats. METHODS Totally 30 qualified male SD rats were randomly assigned to the normal control (NC) group, the pyrexia model (model) group, the Eph, RC and Eph-RC

Anxiolytic-like effect of succinic acid in mice.

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The putative anxiolytic activity of succinic acid was examined in male mice by using a number of experimental paradigms of anxiety and compared with that of the known anxiolytic compound diazepam. Use of the elevated plus-maze test revealed that diazepam (1.0, 2.0 and 4.0 mg/kg, PO) or succinic acid

Incidence of post-pyelonephritic renal scarring: a meta-analysis of the dimercapto-succinic acid literature.

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OBJECTIVE We investigated ethnic differences in the risk of post-pyelonephritic renal scarring in infants and children for possible genetic determinants. METHODS We searched all peer reviewed articles published from 1980 through 2006 in the PubMed(R), MEDLINE(R) (Ovid), Cochrane Central Register of

[Influence of salicylic and succinic acids on formation of active oxygen forms in wheat coleoptiles].

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The comparative study of influence of exogenous salicylic (SaA) and succinic (SuA) acids on the production of reactive oxygen species by isolated wheat coleoptiles has been provided. Under the action of both acids the increase of generation of superoxide anion-radical (O2(.-)) was observed. This

Percutaneous nephrolithotomy in children: early and late anatomical and functional results.

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OBJECTIVE We report our experience with percutaneous nephrolithotomy (PCNL) in children, and evaluate its early and late anatomical and functional results. METHODS A total of 65 children with renal calculi were treated with PCNL. Patient age at operation ranged from 9 months to 16 years (mean +/- SD

High-grade renal injury: non-operative management of urinary extravasation and prediction of long-term outcomes.

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OBJECTIVE To predict the outcomes of a non-operative approach to managing urinary extravasation after blunt renal trauma. METHODS A prospective observational study was conducted between January 2004 and October 2011. First-line non-operative management was proposed for 99 patients presenting with a

[Mechanisms of actoprotective action of succinic acid's derivatives].

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Research on establishment of mechanisms of metabolitotropic compounds' actoprotective action--derivatives of succinic acid yakton and mexidol, based on the definition of their antihypoxic, antioxidant, mitoprotective, and ergogenic properties are presented in this article. In case of hypoxic,

Predictive factors for acute renal cortical scintigraphic lesion and ultimate scar formation in children with first febrile urinary tract infection.

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OBJECTIVE We assessed predictive factors for acute renal cortical scintigraphic lesion and ultimate scar formation in children with a first febrile urinary tract infection. METHODS A total of 89 girls and 138 boys with a first febrile urinary tract infection were included in the study. We analyzed

Co-delivery of doxorubicin and recombinant plasmid pHSP70-Plk1-shRNA by bacterial magnetosomes for osteosarcoma therapy.

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To explore a novel combination of chemotherapy, gene therapy, and thermotherapy for osteosarcoma, a targeted heat-sensitive co-delivery system based on bacterial magnetosomes (BMs) was developed. The optimal culture conditions of magnetotactic bacteria (MTB) AMB-1 and characterization of BMs were

Variable Responses to Carbon Utilization between Planktonic and Biofilm Cells of a Human Carrier Strain of Salmonella enterica Serovar Typhi.

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Salmonella enterica serovar Typhi (S. Typhi) is a foodborne pathogen that causes typhoid fever and infects only humans. The ability of S. Typhi to survive outside the human host remains unclear, particularly in human carrier strains. In this study, we have investigated the catabolic activity of a

Bacterial virulence factors are associated with occurrence of acute pyelonephritis but not renal scarring.

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OBJECTIVE We evaluated the influence of patient factors and virulence factors of uropathogenic Escherichia coli on the occurrence of acute pyelonephritis and subsequent renal parenchymal scarring. METHODS We evaluated 80 boys and 45 girls 1 to 180 months old with febrile urinary tract infections who

Risk factors for renal scar formation in infants with first episode of acute pyelonephritis: a prospective clinical study.

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OBJECTIVE We prospectively determined the risk factors for renal scar formation after the first episode of acute pyelonephritis as confirmed on dimercapto-succinic acid scintigraphy in children younger than 1 year. METHODS A total of 213 infants with acute pyelonephritis were enrolled in the study.

Janus Gold Nanostars-Mesoporous Silica Nanoparticles for NIR-Light-Triggered Drug Delivery.

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Janus gold nanostar-mesoporous silica nanoparticle (AuNSt-MSNP) nanodevices able to release an entrapped payload upon irradiation with near infrared (NIR) light were prepared and characterized. The AuNSt surface was functionalized with a thiolated photolabile molecule (5), whereas the mesoporous

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