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valine/neoplasms

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Manganese superoxide dismutase Val16Ala polymorphism predicts resistance to chemotherapeutic drug cancer therapy

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STATEMENT AS TO RIGHTS TO INVENTIONS MADE UNDER FEDERALLY SPONSORED RESEARCH OR DEVELOPMENT Not applicable BACKGROUND OF THE INVENTION Cancer is the second leading cause of death behind heart disease. In fact, cancer incidence and death figures account for about 10% of the U.S. population in certain

Method of using beta-hydroxy-beta-methylbutyrate for reducing tumor growth rate

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The present invention relates to methods for the prevention and treatment of chronic inflammatory diseases, cancer, and involuntary weight loss. In the practice of the present invention patients are enterally administered HMB alone or alternatively in combination with eicosapentaenoic (20:5

Methods for diagnosing an increased risk for breast or ovarian cancer

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FIELD OF THE INVENTION The present invention relates to methods for diagnosing an increased risk for breast or ovarian cancer by assaying for genetic markers in the human progesterone receptor gene. BACKGROUND OF THE INVENTION Breast cancer is the most frequent malignancy in women. A family history

Peptides for the treatment of cancer

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CROSS-REFERENCE TO RELATED APPLICATIONS This application is a national phase application under 35 U.S.C. .sctn.371 of International Application No. PCT/EP2014/050330 filed 9 Jan. 2014, which claims priority to European Patent Application No. 13150974.7 filed 11 Jan. 2013. The entire contents of each

Peptides for the treatment of cancer

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The present invention relates to an isolated peptide exhibiting antitumoral effects. Every year millions of people are diagnosed with cancer worldwide. Notwithstanding in the last decades much progress has been achieved in cancer therapy, nevertheless cancer remains a leading cause of death.
BACKGROUND OF THE INVENTION The present invention relates to methods and a diagnostic aid for distinguishing a subset of HPV that is associated with an increased risk of developing cervical dysplasia and cervical cancer. Human papillomavirus (HPV) has been identified previously as an important

Inhibitor for liver cancer onset and progress

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BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to pharmaceutical compositions which inhibit the onset or progress of liver cancer. Particularly, the present invention relates to pharmaceutical compositions which inhibit the onset or progress of liver cancer in

Peptide agents for cancer therapy

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FIELD OF THE INVENTION The invention relates to agents for the inhibition of the growth and/or proliferation of cancer cells. BACKGROUND OF THE INVENTION Integrins comprise a family of cell adhesion receptors composed of alpha/beta heterodimeric subunits that provide a functional and structural

Method of using .beta.-hydroxy-.beta.-methylbutyrate for the treatment of disease conditions

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The present invention relates to methods for the prevention and treatment of chronic inflammatory diseases, cancer, and involuntary weight loss. In the practice of the present invention patients are enterally administered HMB alone or alternatively in combination with eicosapentaenoic (20:5

Method of using beta-hydroxy-beta-methylbutyrate for treating disease-associated wasting

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BACKGROUND Undesired weight loss, particularly lean mass loss is a relatively common occurrence in critical illness, and has a significant impact on morbidity and mortality. This is particularly true in cancer patients, where such mass losses can become treatment-limiting, and thus impact overall

HMB uses thereof

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The present invention relates to methods for the prevention and treatment of chronic inflammatory diseases, cancer, and involuntary weight loss. In the practice of the present invention patients are enterally administered HMB alone or alternatively in combination with eicosapentaenoic (20:5

Method of using beta-hydroxy-beta-methylbutyrate and fatty acids for treating disease-associated wasting

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BACKGROUND Undesired weight loss, particularly lean mass loss is a relatively common occurrence in critical illness, and has a significant impact on morbidity and mortality. This is particularly true in cancer patients, where such mass losses can become treatment-limiting, and thus impact overall

.beta.2 microglobulin fusion proteins and high affinity variants

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FIELD OF THE INVENTION This invention relates to compositions based on .beta..sub.2 microglobulin, and the use of such compositions in immunological methods pertaining to the targeting of proteins to cell surfaces. The disclosed compositions and methods have particular application to vaccination and

Polymalic acid-based multifunctional drug delivery system

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BACKGROUND OF THE INVENTION AND DESCRIPTION OF THE PRIOR ART The present invention relates to the field of targeted delivery of drugs and more specifically involves a multifunctional targeted drug delivery vehicle. Currently several different molecular scaffolds are used in the synthesis of drug

Small peptide modulators of potassium channel trafficking

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BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to the design, synthesis, and use of peptide modulators of ion channels. The peptides of the instant invention are useful in modulating ion-trafficking across potassium channels, specifically calcium activated
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