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vincristine/neoplasms
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Pagină 1 din 33 rezultate
FGFR1 extracellular domain combination therapies for lung cancer
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BACKGROUND AND SUMMARY OF THE INVENTION
Soluble forms of Fibroblast Growth Factor Receptor 1 (FGFR1) have been shown to inhibit tumor cell growth in vitro and in vivo. See, e.g., U.S. Pat. No. 7,678,890. Combining an anti-cancer therapeutic molecule, such as a soluble form of FGFR1, with another
Vincristine-containing product
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The present invention relates to a vincristine-containing pharmaceutical product for treating various types of cancer.
Vincristine is a mitosis-retarding Vinca alkaloid which is fairly effective in combating various types of cancer, particularly Hodgkins disease and other types of blood
Histone deacetylase (HDAC) inhibitors for the treatment of cancer
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FIELD OF INVENTION
The present invention relates to methods for treating cancer. In one respect, the present invention relates to a method of treating cancer (e.g., solid tumour cancer, e.g., rectal cancer, colon cancer, ovarian cancer; hematological cancer, e.g., multiple myeloma, leukemia,
Histone deacetylase (HDAC) inhibitors for the treatment of cancer
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FIELD OF INVENTION
The present invention relates to methods for treating cancer. In one respect, the present invention relates to a method of treating cancer (e.g., solid tumour cancer, e.g., rectal cancer, colon cancer, ovarian cancer; hematological cancer, e.g., multiple myeloma, leukemia,
Histone deacetylase (HDAC) inhibitors (PXD101) for the treatment of cancer alone or in combination with chemotherapeutic agent
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RELATED APPLICATION
This application is a national stage filing under 35 U.S.C. 371 of International Application No. PCT/GB2006/004215 filed on 10 Nov. 2006, which is related to U.S. provisional patent application 60/735,701 filed 10 Nov. 2005, the contents of which are incorporated herein by
Anti-cancer combinations
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FIELD OF THE INVENTION
The invention relates to compositions comprising combinations of anti-cancer drugs and methods of using the compositions for the the treatment of cancer.
BACKGROUND
5,6-dimethylxanthenone-4-acetic acid (DMXAA) is represented by the following formula:
##STR00001##
Phase I
Anti-cancer combinations
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FIELD OF THE INVENTION
The invention relates to compositions comprising combinations of anti-cancer drugs and methods of using the compositions for the treatment of cancer.
BACKGROUND
5,6-dimethylxanthenone-4-acetic acid (DMXAA) is represented by the following formula:
##STR00001##
Phase I clinical
Synthesis of vinblastine and vincristine type compounds
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BACKGROUND OF THE INVENTION
The indole-indoline alkaloids, the most important of which can be represented by the compound of formula I ##STR1## wherein R.sub.2 is acetoxy or hydroxy; and R is formyl or methyl; include vinblastine and vincristine, which are anti-tumor agents widely used in the
Synthesis of vinblastine and vincristine type compounds
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BACKGROUND OF THE INVENTION
The indole-indoline alkaloids, the most important of which can be represented by the compound of formula I ##STR1## wherein R.sub.2 is acetoxy or hydroxy; and R is formyl or methyl include vinblastine and vincristine, which are anti-tumor agents widely used in the
In vivo agents comprising cationic drugs, peptides and metal chelators with acidic saccharides and glycosaminoglycans, giving improved site-selective localization, uptake mechanism, sensitivity and kinetic-spatial profiles, including tumor sites
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BACKGROUND OF THE INVENTION
Until recently the localization of intravascular drugs in body tissues has depended on chemical partitioning across microvascular barriers into the tissue compartments of multiple body organs. This resulted in only 0.01% to 0.001% of the injected dose actually reaching
Dose critical in-vivo detection of anti-cancer drug levels in blood
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FIELD OF THE INVENTION
The present invention relates generally to the in vivo detection and measurement of the dose critical levels of certain anti-cancer drugs in blood, serum and other biological fluids, more specifically to the detection of such drugs using a probe DNA and still more specifically
Compounds and compositions for the treatment of cancer
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FIELD OF INVENTION
The present invention relates to the field of medicine. More particularly, the invention relates to compounds, pharmaceutical compositions and uses thereof for the treatment of cancers.
BACKGROUND OF INVENTION
Cancer refers to more than one hundred clinically distinct forms of the
Compounds and compositions for the treatment of cancer
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FIELD OF INVENTION
The present invention relates to the field of medicine. More particularly, the invention relates to compounds, pharmaceutical compositions and uses thereof for the treatment of cancers.
BACKGROUND OF INVENTION
Cancer refers to more than one hundred clinically distinct forms of the
Alkyne-, azide- and triazole-containing flavonoids as modulators for multidrug resistance in cancers
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FIELD OF THE INVENTION
The invention relates to novel alkyne-, azide- and triazole-containing flavonoid compounds, methods of preparing the same, and use of these compounds for reducing multidrug resistance caused by overexpression of ABC transporters.
This invention relates to a new method of
Alkyne-, azide- and triazole-containing flavonoids as modulators for multidrug resistance in cancers
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FIELD OF THE INVENTION
The invention relates to novel alkyne-, azide- and triazole-containing flavonoid compounds, methods of preparing the same, and use of these compounds for reducing multidrug resistance caused by overexpression of ABC transporters.
This invention relates to a new method of
Cea mai completă bază de date cu plante medicinale susținută de știință
- Funcționează în 55 de limbi
- Cure pe bază de plante susținute de știință
- Recunoașterea ierburilor după imagine
- Harta GPS interactivă - etichetați ierburile în locație (în curând)
- Citiți publicațiile științifice legate de căutarea dvs.
- Căutați plante medicinale după efectele lor
- Organizați-vă interesele și rămâneți la curent cu noutățile de cercetare, studiile clinice și brevetele
Tastați un simptom sau o boală și citiți despre plante care ar putea ajuta, tastați o plantă și vedeți boli și simptome împotriva cărora este folosit.
* Toate informațiile se bazează pe cercetări științifice publicate
