[Alpha-tocopherol concentration of the blood plasma and erythrocytes in patients with symptomatic obesity due to hypothalamo-hypophyseal-adrenal diseases].

Healthy persons, patients with noncomplicated alimentary and hypothalamic obesity and those with pubertal dyspituitarism or Icenko-Cushing's disease were studied for serum and erythrocytic levels of alpha-tocopherol. In normal subjects the levels of alpha-tocopherol in the blood serum are increasing with age. In patients with alimentary obesity and pubertal dyspituitarism the percentage of alpha-tocopherol elevation correlates with that of serum lipids and alpha-tocopherol erythrocytic levels are not higher than in normal subjects. In patients with hypothalamic obesity and in particular with Icenko-Cushing's disease relative incompetence of alpha-tocopherol in the blood serum was accompanied by decreased levels of alpha-tocopherol in red blood cells (absolute deficit of alpha-tocopherol in tissues).