Assessment of antidiabetic potential of Musa acuminata peel extract and its fractions in experimental animals and characterisation of its bioactive compounds by HPTLC.

Musa acuminata is a rich source of nutritional food with acclaimed therapeutic uses. Banana pulp has been reported to possess antidiabetic properties. The present study aimed to investigate antidiabetic potential of Musa acuminata peels and its fractions along with diabetic complications. Animals were divided into various groups (n = 6), EMA 100, 200 and 400 mg/kg/day and various fractions 50 and 100 mg/kg/day along with vehicle administered orally to alloxan-induced diabetic rats (n = 6) for 21 days for extract and for 7 days for fractions. Musa acuminata possess antidiabetic potential by reducing plasma glucose by utilising glucose in the periphery and production of hepatic glycogen and further reduce protein catabolism which is responsible for improvement in body weight along with reduction in diabetic complications such as dyslipidemia, peripheral neuropathy and nephropathy. Protective role of Musa acuminata in treatment of diabetes and its complications.