British Journal of Dermatology 1987-Apr
Beneficial effects of danazol on symptoms and laboratory changes in cholinergic urticaria.
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In a double-blind placebo-controlled study, danazol, an attenuated androgen, was effective in reducing exercise-induced weals in cholinergic urticaria. Danazol treatment also caused significant elevations of several protease inhibitors, particularly antichymotrypsin which has been reported previously to be low in cholinergic urticaria.