Zhongguo zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine / Zhongguo Zhong xi yi jie he xue hui, Zhongguo Zhong yi yan jiu yuan zhu ban 1997-Dec

[Study on effects of Codonopsis eupolyphaga anti-obesity powder in mice with nutritive obesity].

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W Wang

D Z Zhao

B H Sun

СТАТЬЯ: 10322823

BioSeek: 10322823

Ключевые слова

triglyceride

переутомление

hypoxia

ожирение

кодонопсис

абстрактный

OBJECTIVE

To observe the effects of Codonopsis Eupolyphaga anti-obesity powder(CEAOP) in mice with nutritive obesity.

METHODS

CEAOP 0.5-2.5 g/kg was given to mice for 4 weeks and its effect was observed.

RESULTS

CEAOP could significantly reduce the Lee's index, weight of fat cushion and fat index, lower the blood levels of total cholesterol, triglyceride and blood glucose, but influence neither the calories and quantity of food intake, nor the endurance against anoxia and fatigue, the property of stool was not changed at all.

CONCLUSIONS

The anti-obesity effect of CEAOP was similar to Fenfluramini but without influence on appetite and bowel movement, tolerance against anoxia and fatigue. The mechanism of the anti-obesity might be related with its metabolism regulating actions on lipids and glucose.