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Страница 1 от 98 полученные результаты
Amine and amide derivatives as ligands for the neuropeptide Y Y5 receptor useful in the treatment of obesity and other disorders
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FIELD OF THE INVENTION
This invention relates to a series of amine and amide derivatives, pharmaceutical compositions containing them and intermediates used in their preparation. The compounds of the invention are ligands for the neuropeptide Y Y5 (NPY5) receptor, a receptor which is associated with
Amine and amide derivatives as ligands for the neuropeptide Y Y5 receptor useful in the treatment of obesity and other disorders
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FIELD OF THE INVENTION
This invention relates to a series of amine and amide derivatives, pharmaceutical compositions containing them and intermediates used in their preparation. The compounds of the invention are ligands for the neuropeptide Y Y5 (NPY5) receptor, a receptor which is associated with
Substituted N-phenyl-5-phenyl-pyrazolin-3-yl amides as cannabinoid receptor antagonists/inverse agonists useful for treating obesity
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FIELD OF THE INVENTION
The present invention provides novel substituted N-phenyl-5-phenyl-pyrazolin-2-yl amides and derivatives thereof as cannabinoid receptor antagonists/inverse agonists and pharmaceutical compositions thereof and methods of using the same for treating obesity, diabetes,
Substituted methylene amide derivatives as modulators of protein tyrosine phosphatases (PTPs)
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FIELD OF THE INVENTION
The present invention is related to substituted methylene amide derivatives of formula (I), in particular for the treatment and/or prevention of metabolic disorders mediated by insulin resistance or hyperglycemia, comprising diabetes type I and/or II, inadequate glucose
2-amino-benzoxazinone derivatives for the treatment of obesity
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The present invention provides known and novel compounds, their use in the inhibition of an enzyme whose preferred mode of action is to catalyse the hydrolysis of an ester functionality (in vivo, as the enzyme naturally occurs), their use in medicine, and particularly in the prevention and/or
2-oxy-benzoxazinone derivatives for the treatment of obesity
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The present invention provides known and novel compounds, their use in the inhibition of an enzyme whose preferred mode of action is to catalyse the hydrolysis of an ester functionality (in vivo, as the enzyme naturally occurs) their use in medicine, and particularly in the prevention and/or
2-oxy-benzoxazinone derivatives for the treatment of obesity
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The present invention provides known and novel compounds, their use in the inhibition of an enzyme whose preferred mode of action is to catalyse the hydrolysis of an ester functionality (in vivo, as the enzyme naturally occurs) their use in medicine, and particularly in the prevention and/or
2-oxy-benzoxazinone derivatives for the treatment of obesity
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The present invention provides known and novel compounds, their use in the inhibition of an enzyme whose preferred mode of action is to catalyse the hydrolysis of an ester functionality (in vivo, as the enzyme naturally occurs) their use in medicine, and particularly in the prevention and/or
2-amino-benzoxazinone derivatives for the treatment of obesity
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The present invention provides known and novel compounds, their use in the inhibition of an enzyme whose preferred mode of action is to catalyse the hydrolysis of an ester functionality (in vivo, as the enzyme naturally occurs), their use in medicine, and particularly in the prevention and/or
2-Oxy-benzoxazinone derivatives for the treatment of obesity
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The present invention provides known and novel compounds, their use in the inhibition of an enzyme whose preferred mode of action is to catalyse the hydrolysis of an ester functionality (in vivo, as the enzyme naturally occurs) their use in medicine, and particularly in the prevention and/or
Amide compounds having MCH-antagonistic activity and medicaments comprising these compounds
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The present invention relates to new amide compounds, the physiologically acceptable salts thereof as well as their use as MCH antagonists and their use in preparing a pharmaceutical preparation which is suitable for the prevention and/or treatment of symptoms and/or diseases caused by MCH or
Amide derivatives and methods for using the same as selective neuropeptide Y receptor antagonists
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BACKGROUND OF THE INVENTION
(1) Field of the Invention
This invention is a method for inhibiting the neuropeptide Y ("NPY") Y5 receptor using a class of amide derivatives. As antagonists of the Y5 receptor, the amide derivatives to are useful in treating obese mammals, mammals with bulimia, for
Amide derivatives and methods for using the same as selective neuropeptide Y receptor antagonists
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BACKGROUND OF THE INVENTION
1. Field of the Invention
This invention is a method for inhibiting the neuropeptide Y ("NPY") Y5 receptor using a class of amide derivatives. As antagonists of the Y5 receptor, the amide derivatives are useful in treating obese mammals, mammals with bulimia, for treating
Fatty acid amides of norfenfluramine and compositions and methods thereof
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The present invention relates to novel fatty acid amides or norfenfluramine which are cholesterol-lowering agents having beneficial side effects. More particularly, the invention is concerned with the long chain fatty acid amides of norfenfluramine which have dual action in reducing elevated
Bicyclic amide derivatives for enhancing glutamatergic synaptic responses
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FIELD OF THE INVENTION
This invention relates to compounds, pharmaceutical compositions and methods for use in the prevention and treatment of cerebral insufficiency, including enhancement of receptor functioning in synapses in brain networks responsible for various behaviors. Imbalances in neuronal
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