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antidiabetic/инфаркт
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Страница 1 от 679 полученные результаты
Antidiabetic treatments and risk of hospitalisation with myocardial infarction: a nationwide case-control study.
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OBJECTIVE
Data on cardiovascular risk associated with different types of antidiabetic treatments are sparse and conflicting. We examined the risk of hospitalisation with myocardial infarction (MI) among patients treated with sulfonylureas, metformin, insulin, any combination and no antidiabetic
Silent myocardial infarction during hypoglycemic coma.
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Hypoglycemia is a common complication of treatment of diabetes mellitus. The potential neurological complications of hypoglycemia as seizures and coma are well-recognized entities. A hypoglycemic episode is a risk factor for a patient with diabetes to have cardiovascular complications. Myocardial
Influence of an antidiabetic treatment with sulfonylurea drugs on long-term survival after acute myocardial infarction in patients with type 2 diabetes. The LAngendreer Myocardial infarction and Blood glucose in Diabetic patients Assessment (LAMBDA).
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BACKGROUND
Patients with type 2 diabetes show a significantly higher mortality after acute myocardial infarction than non-diabetic patients. The influence of sulfonylureas on the survival after acute myocardial infarction is still under debate.
METHODS
Survival of 562 patients, consecutively
Antidiabetic therapy at admission and survival in diabetic patients with acute myocardial infarction.
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Use of Spontaneous Reporting Systems to Detect Host-Medication Interactions: Sex Differences in Oral Anti-Diabetic Drug-Associated Myocardial Infarction.
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Background Medical treatment should be tailored to an individual's characteristics to optimize treatment benefits. We examined whether case-only analyses from spontaneous reporting systems can detect host-medication interactions in oral antidiabetic drug-associated myocardial infarction. Methods and
Discontinuation of antihyperglycemic therapy after acute myocardial infarction: medical necessity or medical error?
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BACKGROUND
A national Medicare database indicated that one in eight older patients with diabetes was discharged off all antihyperglycemic therapy (AHT) following acute myocardial infarction (AMI). This practice was associated with increased one-year mortality, but the reasons for stopping AHT were
Risk and short-term prognosis of myocardial infarction among users of antidiabetic drugs.
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Old sulphonylureas have been linked with adverse cardiovascular effects; however, data on the clinical implications are sparse. We examined the association between use of sulphonylureas and other antidiabetic drugs and the risk and case fatality rate (CFR) of myocardial infarction (MI) in a
Risk of acute myocardial infarction in patients treated with thiazolidinediones or other antidiabetic medications.
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OBJECTIVE
Controversy surrounds the question whether thiazolidinediones (TZDs) increase the risk of acute myocardial infarction (AMI). This study examined risk of AMI in patients with type 2 diabetes mellitus (T2DM) who were taking TZDs or other antidiabetic medications.
METHODS
Using a nested
The prognostic importance of plasma glucose levels and of the use of oral hypoglycemic drugs after myocardial infarction in men.
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The relationship of plasma glucose levels to risk of death over a five-year follow-up period was studied in 2,770 male survivors of myocardial infarction in the placebo group of the Coronary Drug Project (CDP). In univariate analyses, a positive association was observed between mortality rates and
Antihyperglycemic therapy and cardiovascular outcomes after acute myocardial infarction in elderly patients with diabetes.
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OBJECTIVE
Type 2 diabetes mellitus is a clear prognostic marker for increased cardiovascular morbidity and mortality after acute myocardial infarction (AMI). We compared diabetes patients based on therapy used (no pharmacotherapy, those prescribed oral antihyperglycemic agents and those prescribed
Discontinuation of antihyperglycemic therapy and clinical outcomes after acute myocardial infarction in older patients with diabetes.
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BACKGROUND
Patients with diabetes are frequently admitted for acute myocardial infarction (AMI) on antihyperglycemic agents but may be discharged without glucose-lowering therapy. We examined the frequency of this practice and evaluated the associated outcomes of readmission and
A protocol for active surveillance of acute myocardial infarction in association with the use of a new antidiabetic pharmaceutical agent.
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OBJECTIVE
To describe a protocol for active surveillance of acute myocardial infarction (AMI) in users of a recently approved oral antidiabetic medication, saxagliptin, and to provide the rationale for decisions made in drafting the protocol.
METHODS
A new-user cohort design is planned for
[Hypoglycemic encephalopathy demonstrating generalized multiple cortical infarctions--sequential CT findings].
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A fifty-nine-year-old alcoholic man with severe hypoglycemic encephalopathy was examined using sequential CT scans of the brain (CT). Twenty-seven hours after the attack, which resulted in a comatose state, CT disclosed multiple low density areas throughout the cerebral cortex which resembled
Hypoglycemic coma associated with brain infarcts.
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Hypoglycemic hemiplegia may lead to a mistaken diagnosis of stroke, although the symptoms resolve with correction of the hypoglycemia. We report a 27-year-old white man with insulin-dependent diabetes who developed right hemispheric infarcts and left hemiplegia associated with hypoglycemic coma.
A novel anti-diabetic drug, miglitol, markedly reduces myocardial infarct size in rabbits.
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1. We examined whether N-hydroxyethyl-1-deoxynojirimycin (miglitol), a new human anti-diabetic drug with effects to inhibit alpha-1, 6-glucosidase glycogen debranching enzyme and reduce the glycogenolytic rate as well as to inhibit alpha-1,4-glucosidase, could reduce infarct size in the rabbit
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