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Страница 1 от 23 полученные результаты
THE EFFECT OF ACUTE BLEEDING ON CATECHOL AMINE SECRETION.
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The correlation between COMT gene polymorphism and early cerebral vasospasm after subarachnoid hemorrhage.
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BACKGROUND
The individual difference of cerebral vasospasm (CVS) degree after subarachnoid hemorrhage (SAH) is common in clinic observation. Numerous studies have found that early CVS after SAH is associated with derangements in catecholamine (CA) metabolism. Catechol-O-methyltransferase (COMT) is a
Clonidine modulates the ventrolateral medullary catechol metabolic hyperactivity induced by hypotension.
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In vivo electrochemistry allowed recording of a catechol oxidation current in the ventrolateral medulla, caudal to the obex, in anesthetized rats whose ventilatory, metabolic and hemodynamic parameters were rigorously controlled. Hemorrhage or controlled hypotension induced an increase in the
Complete prevention of blood loss with self-sealing haemostatic needles.
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Bleeding is largely unavoidable following syringe needle puncture of biological tissues and, while inconvenient, this typically causes little or no harm in healthy individuals. However, there are certain circumstances where syringe injections can have more significant side effects, such as
Dietary nitrate and reductive polyphenols may potentiate the vascular benefit and alleviate the ulcerative risk of low-dose aspirin.
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The recent revelation that daily low-dose aspirin not only lowers risk for vascular events, but also can notably decrease risk for a range of adenocarcinomas, decreasing total cancer mortality by about 20%, makes it highly desirable to implement this protective strategy on a population-wide basis.
2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) effects on hepatic microsomal steroid metabolism and serum estradiol of pregnant rats.
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Experiments were conducted to evaluate the effects of administration of low, but fetotoxic quantities of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) during pregnancy on steroid metabolism in liver microsomes. Oral administration of 1 microgram X kg-1 X day-1 of TCDD to pregnant rats on days 7-19 of
Red blood cell catecholamine levels in normotensive and DOCA-salt hypertensive rats.
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Under basal conditions in anesthetized rats, significant concentrations of free norepinephrine (NE), epinephrine (E), and dopamine (DA) were detected in red blood cell (RBC) lysate. These concentrations were not proportional to their respective plasma concentrations and thus RBC-to-plasma
The continuous estimation of angiotensin formed in the circulation of the dog.
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1. The use of the rat colon as a blood-bathed organ is described for detecting changes in angiotensin concentration in the circulating blood of dogs.2. Partial occlusion of the aorta by a balloon inflated above the renal arteries leads to a contraction of the blood-bathed rat colon.3. From the
Pharmacophoric characteristics of dengue virus NS2B/NS3pro inhibitors: a systematic review of the most promising compounds.
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Dengue virus (DENV) infection can lead to a wide range of clinical manifestations, including fatal hemorrhagic complications. There is a need to find effective pharmacotherapies to treat this disease due to the lack of specific immunotherapies and antiviral drugs. That said, the DENV NS2B/NS3pro
Observations on the cyclic nucleotide concentrations in human cerebrospinal fluid.
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Previous studies have shown that the concentrations of 3', 5' cyclic adenosine monophosphate (cAMP) and 3', 5' cyclic guanosine monophosphate (cGMP) in cerebrospinal fluid (CSF), brain, or both, are increased by melanotropic peptides and catechol amines, and by cholinergic agents. The present study
Iron as a target of chemoprevention for longevity in humans.
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Iron is universally abundant and no life can exist without it. However, iron levels should be maintained within a narrow range. Iron deficiency causes anaemia, whereas excessive iron increases cancer risk, presumably by free radical generation. Several pathological conditions such as genetic
Tough polyacrylamide-tannic acid-kaolin adhesive hydrogels for quick hemostatic application.
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Adhesive hydrogels for wet and dynamic tissues are important for biomedical applications in order to withstand cyclic loading such as in the case of hemorrhaging control on the curved skins and heart tissues. However, the fabrication of hydrogels with strong mechanical properties, high adhesion
Prenatal depression and stress - risk factors for placental pathology and spontaneous abortion.
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Prenatal stress and depression affects 10-25% of pregnant women and is associated with disruption of fetal neurodevelopment, higher rates of placental abnormalities, preeclampsia, spontaneous abortion, or preterm birth. Markers of genetic vulnerability are catechol-O-methyltransferase, monoamine
Less damaging effect of whisky in rat stomachs in comparison with pure ethanol. Role of ellagic acid, the nonalcoholic component.
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OBJECTIVE
Ellagic acid (EA), one of the polyphenols that are abundantly contained in whisky as a nonalcoholic component, has antioxidant and anti-inflammatory activities. In the present study, we compared the action of whisky and pure ethanol on the rat gastric mucosa, and examined the role of EA in
Urushiol-functionalized mesoporous silica nanoparticles and their self-assembly into a Janus membrane as a highly efficient hemostatic material.
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Quick hemostasis plays a very important role in preventing hemorrhagic shock and death by controlling blood loss from trauma in civil and military accidents. An ideal quick hemostat should have tissue-adhesive functional groups, clotting factor activating components, and a plasma non-permeable
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