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embolism/protease

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Heterocyclic protease inhibitors

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BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to novel compounds that function as proteolytic enzyme inhibitors, and particularly to a new class of thrombin inhibitors. 2. Related Art Proteases are enzymes that cleave proteins at single, specific peptide bonds.

Cyclic oxyguanidine protease inhibitors

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BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to novel compounds that function as enzyme inhibitors, and particularly to a new class of non-peptidic inhibitors of proteolytic enzymes. 2. Background Art Proteases are enzymes that cleave proteins at single,

Cyclic oxyguanidine pyrazinones as protease inhibitors

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BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to novel compounds that function as proteolytic enzyme inhibitors, and particularly to a new class of thrombin inhibitors. 2. Background Art Proteases are enzymes that cleave proteins at single, specific peptide

Cyclic oxyguanidine pyrazinones as protease inhibitors

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BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to novel compounds that function as proteolytic enzyme inhibitors, and particularly to a new class of thrombin inhibitors. 2. Background Art Proteases are enzymes that cleave proteins at single, specific peptide

Aminopyridyl-substituted phenyl acetamides as protease inhibitors

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BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to novel compounds that function as proteolytic enzyme inhibitors, and particularly to a new class of thrombin inhibitors. 2. Related Art Proteases are enzymes that cleave proteins at single, specific peptide bonds.

Thromboresistant materials incorporating pyrazinone protease inhibitors

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BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to novel compounds that function as proteolytic enzyme inhibitors, and particularly to a new class of thrombin inhibitors. 2. Related Art Proteases are enzymes that cleave proteins at single, specific peptide bonds.

Aminoguanidines and alkoxyguanidines as protease inhibitors

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BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to novel compounds that function as enzyme inhibitors, and particularly to a new class of non-peptide inhibitors of proteolytic enzymes. 2. Related Art Proteases are enzymes that cleave proteins at single, specific

Aminoguanidines and alkoxyguanidines as protease inhibitors

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BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to novel compounds that finction as enzyme inhibitors, and particularly to a new class of non-peptidic inhibitors of proteolytic enzymes. 2. Related Art Proteases are enzymes that cleave proteins at single, specific

Aminoguanidines and alkoxyguanidines as protease inhibitors

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BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to novel compounds that function as enzyme inhibitors, and particularly to a new class of non-peptidic inhibitors of proteolytic enzymes. 2. Related Art Proteases are enzymes that cleave proteins at single, specific

Aminoguanidines and alkoxyguanidines as protease inhibitors

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BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to novel compounds that function as enzyme inhibitors, and particularly to a new class of non-peptidic inhibitors of proteolytic enzymes. 2. Related Art Proteases are enzymes that cleave proteins at single, specific

Substituted phenyl acetamides and their use as protease inhibitors

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FIELD The present invention relates to novel compounds that function as proteolytic enzyme inhibitors, and particularly to a new class of thrombin inhibitors. BACKGROUND Proteases are enzymes that cleave proteins at single, specific peptide bonds. Proteases can be classified into four generic

Aminoguanidinyl- and Alkoxyguanidinyl-substituted phenyl acetamides as protease inhibitors

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BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to novel compounds that function as proteolytic enzyme inhibitors, and particularly to a new class of thrombin inhibitors. 2. Related Art Proteases are enzymes that cleave proteins at single, specific peptide bonds.

Heteroaryl protease inhibitors and diagnostic imaging agents

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BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to novel compounds that function as proteolytic enzyme inhibitors and to their use as diagnostic imaging agents. 2. Related Art Proteases are enzymes that cleave proteins at single, specific peptide bonds. Proteases

Process for preparing aminoguanidines and alkoxyguanidines as protease inhibitors

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BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to novel compounds that function as enzyme inhibitors, and particularly to a new class of non-peptidic inhibitors of proteolytic enzymes. 2. Related Art Proteases are enzymes that cleave proteins at single, specific

Heteroaryl aminoguanidines and alkoxyguanidines and their use as protease inhibitors

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BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to novel compounds that function as proteolytic enzyme inhibitors, and particularly to a new class of thrombin inhibitors. 2. Related Art Proteases are enzymes that cleave proteins at single, specific peptide bonds.
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