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heparin/некроз

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Low molecular weight heparin-induced skin necrosis-a systematic review.

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BACKGROUND Low molecular weight heparins (LMWHs) are currently used as a standard for anti-thrombotic therapy. Skin necrosis caused by LMWH is a rare and probably under-reported complication. The aim of our systematic review is to analyse the present literature for cases of LMWH-induced skin

Thrombotic complications of heparin therapy: including six cases of heparin--induced skin necrosis.

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Thrombotic complications of heparin administration were observed in eight patients during a two year period. At sites of subcutaneous heparin injection, six patients developed areas of the skin and subcutaneous necrosis. Systemic thrombotic events and thrombocytopenia were observed in two of these

Heparin-induced skin necrosis: nurses beware.

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As the prophylactic use of heparin continues to increase, nurses must be aware that heparin use may cause heparin-induced skin necrosis--a rare but serious complication. Although even more severe complications may occur from heparin use, this discussion will focus on skin necrosis caused by

Heparin-associated skin necrosis.

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A case of skin necrosis at the sites of injection of subcutaneous heparin is described. The patient went on to develop heparin-induced thrombocytopenia and pulmonary embolism. Review of the previously described cases of heparin-associated skin necrosis reveals that this sequence of events is not

Heparin necrosis. An anticoagulation syndrome.

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Lesions indistinguishable from coumarin necrosis developed in three patients who were given heparin sodium subcutaneously. Two of the patients had received only heparin while another had also received coumarin. Heparin necrosis should be added to the list of complications of anticoagulation therapy.

Cutaneous heparin necrosis in a patient with heterozygous protein S deficiency.

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A patient with heterozygous protein S deficiency experienced cutaneous necrosis following subcutaneous heparin administration. Deficiencies of both protein C and protein S, known risk factors for the more frequently encountered coumarin necrosis, may predispose patients to this complication of

Successful administration of low molecular weight heparin in a patient with heparin-induced thrombocytopenia and coumarin-induced skin necrosis.

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A case of heparin-induced thrombocytopenia and skin necrosis induced by coumarin is reported in a 58-year-old female patient suffering from metastatic breast adenocarcinoma and deep vein thrombosis. The thrombosis resolved after treatment with low molecular weight heparin and the thrombocytopenia

[Dermal necrosis as cutaneous manifestation of heparin-induced thrombocytopenia II?].

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Most of the rare cases of skin necrosis following heparin injections are associated with the immunologically mediated form of heparin-induced thrombocytopenia II (HIT II). We present a 62-year- old woman who developed a necrotic abdominal lesion seven days after starting daily subcutaneous

Delayed-onset heparin-induced skin necrosis: a rare complication of perioperative heparin therapy.

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An uncommon case of delayed-onset dalteparin-induced skin necrosis in an 83-year-old Caucasian female patient associated with heparin-induced thrombocytopaenia (HIT) presenting on day 30 following dalteparin therapy is reported. Investigations revealed mild thrombocytopaenia with normal protein C,

Skin necrosis following subcutaneous heparin injection.

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Heparin-induced skin necrosis is a rare but serious complication of subcutaneously administered heparin. Previous reports indicate that the skin necrosis is often accompanied by thrombocytopenia and occasionally by lethal thromboembolism. It thus shows features similar to the heparin-induced

Low-molecular-weight heparin-induced skin necrosis.

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We report a case of low-molecular-weight heparin (LMWH)-induced skin necrosis in a patient with chronic lymphatic leukemia. The patient had heparin-PF4 antibodies and the heparin-induced platelet activation (HIPA) test was positive, but platelet counts remained normal. Analysis of seven cases of

Skin necrosis due to intravenous heparin.

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A patient on intravenous heparin is described who developed an acute hemorrhagic necrosis of her legs. Thrombi without vasculitis were seen in the dermal blood vessels. This appears to be the 4th reported case of skin necrosis after intravenous heparin at sites unrelated to injections. Skin necrosis

Low-molecular-weight heparin-induced skin necrosis: about 2 cases.

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Heparin-induced skin necrosis is an infrequent condition, complicating unfractionated heparin and more rarely low-molecular-weight heparin administration. Like heparin-induced thrombocytopenia, it is associated with the presence of anti-PF4 antibodies. After reporting 2 observations, we briefly

Low Molecular Weight Heparin Induced Skin Necrosis without Platelet Fall Revealing Immunoallergic Heparin Induced Thrombocytopenia.

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Low molecular weight heparins (LMWH) are commonly used in the ICU setting for thromboprophylaxis as well as curative decoagulation as required during renal replacement therapy (RRT). A rare adverse event revealing immunoallergic LMWH induced thrombopenia (HIT) is skin necrosis at injection sites. We

Cutaneous cholesterol emboli with infarction clinically mimicking heparin necrosis--a case report.

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Cutaneous necrosis secondary to anticoagulation (heparin and warfarin) and cholesterol (atheromatous) emboli can be similar clinically and histologically. A unique case is reported of cholesterol emboli clinically mimicking heparin necrosis. The patient was a 57 year old white male who underwent
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