Open Label Study. All participants had BV and took metronidazole 500 mg po BID for 7 days.

Metronidazole

Sex: Female, Male

Region of Enrollment

The study will evaluate HIV infection and safety of cervico-vaginal tissue in women at 3 different time periods:
During a BV infection
Approximately 1 week after completing a 7-day course of metronidazole therapy
Approximately 1 month after completing the 7-day course of metronidazole therapy
Each of the 33 participants were sampled at baseline (during BV infection), approximately 1 week after treatment and approximately 1 month after treatment. p 24 antigen data was not evaluable in this study due to the fact that the samples were frozen prior to laboratory analyses, which damaged the samples. No data were collected.

p24 Antigen Production in Tissue

p 24 antigen data was not evaluable in this study due to the fact that the samples were frozen prior to laboratory analyses.

p24 Antigen Production at Baseline Versus After Treatment With Metronidazole

Overall Study

Andrea Thurman

Bacterial Vaginosis

Vaginal Discharge

All participants had BV at baseline. They all received metronidazole 500 mg po BID for 7 days

Eastern Virginia Medical School CONRAD Clinical Research Center

Study of How Bacterial Vaginosis and Its Treatment Affects Cervical and Vaginal Tissue

Prospective Evaluation of the Impact of Bacterial Vaginosis and Its Treatment on Mucosal Susceptibility to HIV-1 Infection and Endpoints of Cervico-Vaginal Safety

Cohort data will be published but not IPD

Annie Thurman

Associate Professor of OBGYN

CONRAD

Dartmouth-Hitchcock Medical Center

This is an open label study - there was no masking

Cardiovascular Diseases

Coronary Disease

Cerebrovascular Accident

Heart Diseases

Myocardial Infarction

Infection

Chlamydia Infections

Cytomegalovirus Infections

Helicobacter Infections

Atherosclerosis

Infection and Cardiovascular Disease

National Heart, Lung, and Blood Institute (NHLBI)

herpes genitalis

никотин

nicotine

herpes genitalis/никотин

Study of How Bacterial Vaginosis and Its Treatment Affects Cervical and Vaginal Tissue

Infection and Cardiovascular Disease

Самая полная база данных о лекарственных травах, подтвержденная наукой