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hyperuricemia/hypoxia

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Neonatal hyperuricemia.

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Serum concentrations and urinary excretion of uric acid were measured in ten normal newborn infants and in 13 patients with the idiopathic respiratory distress syndrome. In the normal infants, serum urate increased from a mean value of 6.0 mg/dl in cord blood to 7.0 mg/dl at 24 hours, followed by a

Hyperuricemia in an infant with Taussig-Bing anomaly and interruption of the aortic arch.

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Hyperuricemia is commonly recognized in adolescents and adults with cyanotic congenital heart disease. We report a case of a male infant with hyperuricemia, Taussig-Bing anomaly, and interruption of the aortic arch. The patient underwent correction of interrupted aortic arch and pulmonary arterial

Gout and hyperuricemia associated with sickle-cell anemia.

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Since the initial description, in 1958, of gouty arthritis occurring in association with SCA, more than 12 cases have been reported. The high proportion of women and the relatively young ages are noteworthy. Since 1968, studies of patients with SCA have shown a high prevalence of hyperuricemia,

Hyperuricemia in rats during acute carbon monoxide poisoning.

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The effect of carbon monoxide (CO) inhalation on plasma levels of uric acid and hypoxanthine in rats was investigated. Exposure to 3% CO caused respiratory arrest within about 2 minutes. The plasma uric acid level of CO-treated rats increased to 157% above that of ether-treated rats. When rats were

A daytime normotensive patient with nocturnal hypoxia-induced hypertension and severe obstructive sleep apnea.

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This is the case of a 60-year-old male. He had no past medical history at a regular medical check-up. According to findings at the regular medical check-up, he was obese (body mass index, 32.8 kg/m2), and had short neck, small jaw, and low soft palate; therefore, it was suspected that he may have

Hyperuricemia reflects global Fontan pathophysiology and associates with morbidity and mortality in patients after the Fontan operation.

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BACKGROUND Serum uric acid (UA, mg/dl) levels associate with the pathophysiology and prognosis in patients with chronic heart failure. OBJECTIVE To clarify the clinical significance of hyperuricemia (HUA, UA>7.0) in Fontan patients. RESULTS We prospectively measured UA in 197 child and 102 adult

Hyperuricemia, hypertension, and proteinuria associated with high-altitude polycythemia.

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Chronic exposure to high altitude is associated with the development of erythrocytosis, proteinuria, and, in some cases, hyperuricemia. We examined the relationship between high-altitude polycythemia and proteinuria and hyperuricemia in Cerro de Pasco, Peru (altitude, 4,300 m). We studied 25 adult

[Hyperuricemia in chronic heart failure].

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Development of hyperuricemia is associated with excessive body mass, insulin resistance, metabolic syndrome, overuse of diuretics, elderly age, and abnormal renal function. Data are accumulated on existence of links between elevated uric acid level and arterial hypertension, diabetes mellitus,

Hyperuricemia and xanthine oxidase in preeclampsia, revisited.

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Hyperuricemia is associated with the severity of preeclampsia and with fetal outcome. Traditionally the high uric acid concentration in preeclampsia has been attributed soley to renal dysfunction. Preeclampsia is also characterized by increased free radical formation and elevated oxidative stress.

Variation of rat serum biochemical values following decapitation or anesthesia with ether, halothane or Innovar-VetR: rapid Innovar-VetR-induced hyperuricemia and hyperglycemia.

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True reference values (TRV) should ultimately be determined in blood from inactive, unstimulated rats but in practice, acceptable reference values (ARV) may be established using blood from decapitated or anesthetized animals if one is cognizant of variations associated with blood sampling

PP026. Hyperuricemia in the prognosis of adverse perinatal outcomes.

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BACKGROUND Elevated uric acid levels during the first or third trimester of gestation have been associated with poor perinatal outcomes in women with hypertensive pregnancies. OBJECTIVE Investigate whether uric acid levels are related to adverse perinatal outcomes in Chilean hypertensive

Hyperuricemia in acute illness: a poor prognostic sign.

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To clarify the role of the serum urate level and its change as a potential marker for severe tissue hypoxia, we have measured serum urate levels and urine uric acid excretion in 16 patients with acute cardiovascular disease. The six patients who died had a baseline mean serum urate level of 11.1

Urate oxidase in prevention and treatment of hyperuricemia associated with lymphoid malignancies.

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Standard prophylaxis and treatment of malignancy-associated hyperuricemia in the USA has been allopurinol with vigorous hydration, urinary alkalinization and osmotic diuresis. Urate oxidase, the enzyme that converts uric acid to allantoin (a readily excreted metabolite that has 5- to 10-fold higher

Hyperuricemia as a prognostic factor in pulmonary arterial hypertension.

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Pulmonary arterial hypertension is a malignant disease with a median survival of 3 years. Uric acid levels are elevated in severe heart failure and in states of hypoxemia. Early data suggest a correlation between hyperuricemia and severe pulmonary arterial hypertension. We studied 29 patients with

Hyperuricemia in Children and Adolescents: Present Knowledge and Future Directions.

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Recent evidence suggests that hyperuricemia is an important condition in children and adolescents, particularly in association with noncommunicable diseases. This review aims to summarize our current understanding of this condition in pediatric patients. An analysis of serum uric acid reference
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