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Homozygous alpha-thalassaemia and hypospadias--common aetiology or incidental association? Long-term survival of Hb Bart's hydrops syndrome leads to new aspects for counselling of alpha-thalassaemic traits.

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Fetuses with homozygous alpha-thalassaemia develop Hb Bart's hydrops fetalis syndrome, which usually leads either to abortion or fetal/neonatal death. We report diagnosis, intrauterine transfusion therapy, neonatal intensive care management and long-term follow-up of a Vietnamese infant who survived

Congenital contractures, edema, hyperkeratosis, and intrauterine growth retardation: a fatal syndrome in Hutterite and Mennonite kindreds.

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We present clinical findings in infants from three kindreds (two Hutterite and one Mennonite) with an apparently unique, fatal disorder. The major manifestations consist of severe intrauterine growth retardation, congenital contractures, and tense skin which is easily eroded. The skin is tightly

Outcomes and morbidities of patients who survive haemoglobin Bart's hydrops fetalis syndrome: 20-year retrospective review.

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Haemoglobin Bart's hydrops fetalis syndrome was once considered a fatal condition. However, advances over the past two decades have enabled survival of affected patients. Data relating to their morbidities and outcomes will help medical specialists formulate a management plan and parental

A comparative study of surgical outcomes using a Colorado microdissection needle versus standard-size needle electrocautery in one-stage hypospadias repair using a transverse preputial island flap.

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BACKGROUND The purpose of this study was to compare the surgical outcomes of a Colorado microdissection needle (CMN) with that of a standard-size electrocautery needle in one-stage hypospadias repair using a transverse preputial island flap (TPIF). METHODS The records of patients who received

Complications of hypospadias surgery.

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Hypospadias repairs are performed in a unique environment with unique tissue. The potential for edema is tremendous. Given the difficult conditions, there will probably never be an operation for hypospadias that will be uniformly and totally successful. Nevertheless, the authors provide a

Hypospadias surgery: the X-shaped elastic dressing.

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An effective, easily fashioned, adherent, long-term X elastic dressing is described. The dressing has been used predominantely in hypospadias operations. It affords excellent compression of the skin and glandular flaps, and reduces edema. The dressing provides for children comfort, freedom of motion

Homozygous alpha-thalassemia associated with hypospadias in three survivors.

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We report three cases of homozygous alpha-thalassemia (alphaTH) who survived beyond the neonatal period, all with hypospadias. A review of literature identified two additional male cases of homozygous alphaTH who survived, and both had hypospadias. The simultaneous occurrence of the two conditions

Association of hypospadias and cardiac defect in a Parvovirus B19-infected stillborn: a causality relation?

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Parvovirus B19 intrauterine infection is a known cause of hydrops fetalis and fetal death. It is also associated with congenital malformations, although the teratogenic potential seems to be low. Postmortem examination of a male stillborn of 29 gestational weeks revealed mild subcutaneous edema,

Hypospadias repair without a bladder drainage catheter.

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We report on 44 consecutive patients who underwent 1-stage hypospadias repair based on a urethral splent (silicone pleated stent). The severity of hypospadias ranged from subcoronal in 12 cases and distal in 23 to midshaft in 4 and penoscrotal in 5. In the first 15 patients of this series the splent

Hypospadias repair: a single centre experience.

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Objectives. To determine the demographics and analyze the management and factors influencing the postoperative complications of hypospadias repair. Settings. Hayatabad Medical Complex Peshawar, Pakistan, from January 2007 to December 2011. Material and Methods. All male patients presenting with

Cyanoacrylate glue dressing for hypospadias surgery.

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BACKGROUND Hypospadias repair is a common pediatric operation. Several kinds of dressings are currently available, with their benefits and side effects. OBJECTIVE The aim of our study was to introduce a new method of dressing, by pouring several layers of cyanoacrylate (CA) glue as the dressing, in

Outcome of urethroplasty after parenteral testosterone in children with distal hypospadias.

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BACKGROUND Pre-operative testosterone use in hypospadias surgery is known to increase penile dimensions and vascularity, which should facilitate tension-less formation of the urethral tube and tissue healing. However, androgens can have a negative effect on wound healing. There are very few

[Advantages of the anterior and mid-shaft hypospadias repair in the first year of life].

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OBJECTIVE Only a few studies have been performed on the evaluation of complications strictly related to the age at operation of hypospadias repair. The aim of our study was to evaluate the incidence of complications of surgical treatment of anterior and midshaft hypospadias in relation to the age at

Glanuloplasty by ventral skin interposition in hypospadias repair: preliminary report.

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OBJECTIVE It was our aim in this study to develop a technique that is rather simple, overcomes the problems of Devine and Horton glanuloplasty in patients with small glans, and is flexible to be tailored to any hypospadias surgery. METHODS A total of 11 patients were included in this preliminary

Surgical repair of anterior hypospadias with fish-mouth meatus and intact prepuce based on anatomical characteristics.

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OBJECTIVE A variant form of anterior hypospadias, called a megameatus and intact prepuce (MIP), is thought to be less amenable to conventional distal hypospadias repair. The feasibility of using the standard technique with a parameatal-based foreskin flap is described herein. METHODS Nine children

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