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The Effectiveness in the Treatment of Long Bone Defect Using 3D-printed Implant

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The participant with long bone defect or bone tumor of the extremity is referred to the Radiology Department to have a full CT-scan of both limbs to facilitate the later reconstruction. With the contralateral limb CT-scan data, the implant is designed with appropriate geometry and structures through

Risk Factors of Postoperative Complications in HCM Patients

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This study is a single center retrospective observational study designed to assess the in-hospital PCs rate of HOCM patients and to identify perioperative risk factors of PCs in patients who underwent septal myectomy. Ethical approval of this study was obtained from the Institutional Review Board of

Effect of Dexmedetomidine on Brain Homeostasis and Neurocognitive Outcome

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Each participant will receive standard monitoring (ECG, SpO2, SBP, BIS, urine output, temperature). More detailed hemodynamic monitoring will be obtained by Edwards Lifesciences ClearSight system (CO, CI, SV, SVI, SVV, SVR, SVRI). TCI Propofol and Remifentanil will be the agents of choice for

Correlation of NLRP3 With Cognitive Dysfunction Early After Heart Valve Replacement Surgery

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90 consecutive patients scheduled for mitral valve replacement or aortic valve replacement under moderate hypothermic CPB gave written informed consent and were enrolled in this study. In the operating room, patients received routine monitoring. Systemic arterial blood pressure was measured via

Non-invasive Ventilation vs Oxygen Therapy After Extubation Failure

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Patients. Medical and surgical patients admitted to intensive care unit with 18 years of age or older in weaning from their first episode of mechanical ventilation for more than 24 hours were included. Patients with structural neurological disorder, acute toxic-metabolic neurological encephalopathy

DRUG ELUTING STENT FOR DIABETIC PATIENTS IN CORONARY ARTERY DISEASE TREATMENT

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DEDICATE Registry: DRUG ELUTING STENT FOR DIABETIC PATIENTS IN CORONARY ARTERY DISEASE TREATMENT A POST MARKET REGISTRY OF ABLUMINUS® SIROLIMUS ELUTING CORONARY STENT SYSTEM FOR PERCUTANEOUS INTERVENTION IN PATIENTS WITH DIABETES MELLITUS Version 1.0 Principal Investigator Dr. Luca Testa, MD, PhD

Study to Evaluate the Efficacy & Safety of the INTERCEPT Blood System for RBCs in Complex Cardiac Surgery Patients

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This is a prospective, multicenter, randomized, double-blinded, active controlled, parallel-design, non-inferiority study. Screening/Recruitment In order to minimize the number of patients who enroll in the study but do not require RBC transfusion, only patients with a relatively high likelihood to

Haemostasis Management of Abdominal Aortic Procedures

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Despite the fact that interventional therapy of vascular lesions (endovascular and hybrid procedures) is becoming more and more common, angioplasties involving major vessels have to be still managed as surgical procedures associated with extreme high demand for transfusion, this applies especially

The Impact of Cervical Cerclage or Vaginal Progesterone on Vaginal Microbiome Distribution

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Cervical insufficiency is primarily a clinical diagnosis, characterized by painless cervical dilation leading to recurrent second-trimester pregnancy losses/births of otherwise normal pregnancies. Adverse perinatal events associated with cervical insufficiency include prolapse of the fetal membranes

Comparative Analysis Between Ringer's Lactate vs Plasma Lyte-A as Cardiopulmonary Bypass Prime

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REVIEW OF LITERATURE The ideal prime for Cardiopulmonary Bypass (CPB) has never been fully established. The development of acid-base disorders during some routine cases and the possible contribution to this from priming fluids caused this hospital to question its protocol. Plasma Lyte-A injection,

The Inter and Intra Reliability of Cardiopulmonary Exercise Testing in Abdominal Aortic Aneurysm Patients

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Background Research: The definition of an 'aneurysm' is permanent, localised dilatation of a blood vessel or heart chamber. The abdominal aorta is the largest blood vessel in the human body and usually has a diameter of 1.8 -2.0 centimetres (cm), dependant on age, sex and body habitus. Aortic

Fluid Resuscitation Optimization in Surgical Trauma Patients (FROST)

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Numerous factors are known to contribute to post-traumatic morbidity and mortality. Acute blood loss, hypovolemia, and systemic inflammatory response syndrome can often develop following severe traumatic injury and are, frequently, further exacerbated by the presence of pre-existing health

Safety, Tolerability and Efficacy of Vaginal Suppository WO3191 in the Post-treatment of Bacterial Vaginosis

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This investigation is a multicentre, parallel-group, double-blind, controlled trial with an open Follow-up Phase of 12 weeks. It is conducted to gain clinical experience and further knowledge about the certified medical device Vaginal suppository WO3191 in women with bacterial vaginosis. In this

L-ornithine L-aspartate in Overt Hepatic Encephalopathy

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A. Introduction and Review of literature Hepatic encephalopathy (HE) is broadly defined as an alteration in mental status and cognitive function occurring in presence of liver failure. The clinical picture of HE arises as a complication of chronic and, more rarely, acute liver disease. HE occurs in

Randomized Trial of Pulsatile vs Non Pulsatile Perfusion on Short Term Changes in Kidney Function Using an Intra-Aortic Ballooon Pump During Cardioplegic Arrest in Patients Undergoing Myocardial Reperfusion

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Linear flow during cardiopulmonary bypass (CPB) frequently induces renal damage. We will evaluate whether automatic intra-aortic balloon pump (IABP) induced pulsatile perfusion preserves renal function in patients undergoing myocardial revascularization at different risk for renal damage. 100

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