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monosaccharide/злокачественная опухоль

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Synthetic C-glycolipid and its use for treating cancer, infectious diseases, and autoimmune diseases

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FIELD OF THE INVENTION The invention is directed to novel synthetic C-glycolipids, which are useful in treating cancer, infectious diseases and autoimmune diseases. Specifically, the invention is directed to novel synthetic analogs of .alpha.-C-galactosylceramides, which are potent mediators of

Synthetic C-glycolipid and its use for treating cancer, infectious diseases and autoimmune diseases

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FIELD OF THE INVENTION The invention is directed to novel synthetic C-glycolipids, which are useful in treating cancer, infectious diseases and autoimmune diseases. Specifically, the invention is directed to novel synthetic analogs of .alpha.-C-galactosylceramides, which are potent mediators of

Therapeutic method for selectively treating terminal deoxynucleotidyl transferase-positive neoplastic leukemias and lymphomas

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FIELD OF THE lNVENTION The present invention is concerned with anti-cancer therapies which utilize selective DNA polymerase substrate analogues as the basis for treatment and is directed to specific means for selectively employing the activity of terminal deoxynucleotidyl transferase, the unique DNA

Use of fructose-based compounds for the diagnosis of cancer

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FIELD OF INVENTION This invention relates to compositions, methods utilizing fructose and other monosaccharides for the diagnosis of cancer. BACKGROUND All publications herein are incorporated by reference to the same extent as if each individual publication or patent application was specifically

Synthetic glycoamines and methods for their use that affect cell adhesion, inhibit cancer cell metastasis, and induce apoptosis

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FIELD OF THE INVENTION The present invention relates to pharmaceuticals that affect cell adhesion, inhibit cancer cell metastasis, and induce apoptosis both in vitro and in vivo. Background of the Invention Cell adhesion is one important property that differentiates multi-cellular organisms from

Ameliorant for chemical treatment of cancer

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TECHNICAL FIELD This invention relates to a novel ameliorating agent for cancer chemotherapy. More particularly, this invention relates to an ameliorating agent for cancer chemotherapy containing as an active ingredient a water-soluble chromanol glycoside. BACKGROUND ART Cancers have been a disease

Monosaccharide derivatives

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CROSS-REFERENCE TO RELATED APPLICATIONS This application claims priority to foreign patent application 1310/DEL/2006, filed May 30, 2006 in India. FIELD OF THE INVENTION The present invention relates to monosaccharide derivatives as anti-inflammatory agents. The compounds disclosed herein can be

Glycopeptide for contrast agent targeting cancer cells and contrast agent kit containing the same

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CROSS-REFERENCE TO RELATED APPLICATIONS This application claims, under 35 U.S.C. .sctn. 119, the priority of Korean Patent Application No. 10-2015-0081418, filed on Jun. 9, 2015 in the Korean Intellectual Property Office, the disclosure of which is incorporated herein by reference in its

Method for treating tumors using cis-diammineplatinum (II) organophosphate complexes

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This invention is concerned with cis-diammineplatinum(II) organophosphate complexes. More particularly, this invention is concerned with cis-diammineplatinum(II) organophosphate complexes, where the organophosphate moiety is either a glycerophosphate or a monosaccharide phosphate. These complexes

Levo-monosaccharide in a nucleoside analog for use as an anti-retroviral agent

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BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to compositions and methods for inhibiting reverse transcription, and, more particularly, to such compositions and methods for creating a nucleoside analog that disrupts the hybridization step during reverse

Acetates of 2-deoxy monosaccharides with anticancer activity

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BACKGROUND OF THE INVENTION Reliance on glycolysis has been correlated with disease progression in cancer, and as well as a consistent and significant increase in activity of hexokinase, phosphofructokinase and pyruvate kinase. Hypoxia is also a feature of many solid cancers and has been linked to

Methods and compositions for treatment of cell proliferative disorders

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1. INTRODUCTION The present invention relates to methods and compositions comprising at least one endothelin antagonist, preferably in combination with a poly-.beta.-1.fwdarw.4-N-acetylglucosamine (p-GlcNAc) polysaccharide matrix, for use in the treatment of cancer and other proliferative diseases.

Method of treating angiogenesis

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Growth factors comprise a family of polypeptides with a manyfold of properties regulating for example cell proliferation and cell metabolism. As being multi-functional molecules, they may stimulate or inhibit cell proliferation as well as affect cell function depending on the type of the target

Synthetic lipid-a-analogs and uses thereof

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FIELD OF THE INVENTION The present invention relates to novel synthetic structural mimics of bacterial Lipid-A and methods of synthesis of such analogs. Bacterial Lipid-A compositions are being widely used as adjuvant to enhance the immune responses to various antigens used in vaccine formulations.

Tetraphenylbacteriochlorin derivatives and compositions containing the same

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TECHNICAL FIELD The present invention relates to tetraphenylbacteriochlorin derivatives, particularly, tetraphenylbacteriochlorin derivatives substituted by monosaccharide residues and their salts, a method of producing the same and compositions as photosensitizers containing the same, especially
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