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nitrate/инфаркт

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High-dose nitrate therapy recovers the expression of subtypes α1 and β-adrenoceptors and Ang II receptors of the renal cortex in rats with myocardial infarction-induced heart failures.

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Few studies examined the effect of long-acting nitrates on renal function in chronic heart failure (CHF). Thus, we aimed to investigate the effect of long-acting nitrate on the expression of adrenoceptors (AR) and angiotensin II receptor (ATR) subtypes of the renal cortex, in rats with

Long-term nitrate therapy after acute myocardial infarction does not improve or aggravate prognosis.

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BACKGROUND There is conflicting information about whether nitrate treatment aggravates long-term prognosis, so the present retrospective study was designed to determine the effects of long-term nitrate therapy on major adverse events after acute myocardial infarction (AMI) in the coronary

Acute myocardial infarction following sildenafil citrate (Viagra) intake in a nitrate-free patient.

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Since its introduction to the market in March 1997, sildenafil acetate (Viagra) has been prescribed to 1.7 million people. Sixteen men who were taking the drug have died, 7 of them during or soon after sexual activity. Most of these data have been derived from the media and not from the scientific

Detection of hibernate myocardium by 99mTc sestamibi gated SPECT during low-dose dobutamine infusion plus nitrate in patients with first acute myocardial infarction.

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OBJECTIVE To investigate the role of Tc-MIBI gated SPECT imaging following the administration of low-dose dobutamine plus nitrate (LDD+nitrate) in the assessment of left ventricular function and the perfusion of hibernate myocardial tissue. METHODS The study group comprised 29 patients diagnosed as

[Dose and time dependence of hemodynamic tolerance development during intravenous nitrate therapy in acute myocardial infarct].

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Intravenous nitroglycerin therapy during acute myocardial infarction has beneficial effects on infarct size, infarct complications, and mortality. Numerous dosage formulas for the continuous administration of nitrates are currently used, although several studies have demonstrated the rapid

The cerebrospinal fluid oxidized NO metabolites, nitrite and nitrate, in Alzheimer's disease and vascular dementia of Binswanger type and multiple small infarct type.

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The concentration of the nitric oxide (NO) metabolites nitrite (NO2-) and nitrate (NO3-) in the cerebrospinal fluid from patients with Alzheimer's disease (AD), vascular dementia of the Binswanger type (VDBT) or multiple small infarct type (MSID), and controls were determined using high performance

Acute myocardial infarction following sildenafil intake in a nitrate-free patient without previous history of coronary artery disease.

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OBJECTIVE To report the occurrence of acute myocardial infarction (MI) associated with the intake of oral sildenafil (Viagra) in a nitrate-free patient without previous history of coronary artery disease. METHODS A 50-year-old manual laborer was admitted to the hospital with acute inferoposterior

[The echo-nitrate test for the detection of viable myocardium after a myocardial infarct: a comparison with delayed-acquisition thallium scintigraphy].

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BACKGROUND The aim of this study was to evaluate the ability of echocardiography, associated with nitroglycerin infusion, in the detection of myocardial viability in patients with recent infarction. METHODS Fourteen patients (11 male, 3 female, mean age 59 +/- 8 years) with first acute myocardial

[Lack of tolerance development with low dose nitrate administration in acute myocardial infarct].

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Reports on the development of tolerance have modified the use of nitrates in the treatment of coronary heart disease. Dosage limitations and nitrate-free intervals are frequently recommended to solve this problem (4, 5). In the clinical setting of acute myocardial infarction continuous application

Effects of long-term transdermal nitrate treatment on left ventricular function in patients following myocardial infarction.

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BACKGROUND [corrected] Nitrates are widely used for the treatment of myocardial infarction (MI). The large megatrials (GISSI-3 and ISIS-4) did not in fact demonstrate a significant decrease in mortality in the nitrate-treated group. However, examination of the number of postinfarction angina

Effects of nitrates on mortality in acute myocardial infarction and in heart failure.

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1. Seven randomized controlled trials of intravenous nitroglycerin in a total of about 850 patients have been reported. Overall, there were 51 deaths (12.5%) in the nitroglycerin group and 87 (20%) in the control group. This indicates a 48% reduction in the odds of death (P less than 0.001, 95%

Effect of prolonged nitrate therapy on left ventricular remodeling after canine acute myocardial infarction.

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BACKGROUND Prolonged nitrate therapy during healing between 2 days and 6 weeks after anterior myocardial infarction has the potential for limiting further left ventricular remodeling (or changes in topography) and preserving function. Longterm therapy throughout healing over 6 weeks might be more

Coronary arteriographic findings during early hours of acute myocardial infarction: response to intracoronary injection of nitrates.

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We performed coronary arteriography and gave intracoronary injection of nitrates within 8 hours after the onset of symptoms of acute myocardial infarction in eighteen patients. Improved distal filling or patency of the total occluded coronary artery after intracoronary injection of nitrates occurred

Long-term, continuous treatment with both oral and transdermal nitrates increases cardiac events in healed myocardial infarction patients.

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This study was performed to investigate the effects of continuous dosing of oral, transdermal (patch), and a combination of the two with nitrate treatments on cardiac events in patients with healed myocardial infarction. In total, 1,291 patients with healed myocardial infarction were assigned 2

Chronic use of continuous dosing of long-term nitrates does not prevent cardiac events in patients with severe acute myocardial infarction.

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This study was performed to investigate the effects of the chronic use of continuous, not eccentric, dosing of nitrates on cardiac events in patients with severe acute myocardial infarction. A total of 1,303 patients with healed myocardial infarction were divided into two groups: treatment with
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