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osteoarthritis/tyrosine

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Protein tyrosine kinase inhibitors for treating osteoarthritis

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BACKGROUND Osteoarthritis or degenerative joint disease is a slowly progressive, irreversible, often monoarticular disease characterized by pain and loss of function (Mankin and Brandt, Pathogenesis of Osteoarthritis in "Textbook of Rheumatology", Kelly, et al., (eds.) 3rd edition, W. B. Saunders

Class of arylamide compounds useful as inhibitors of c-fms kinase

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CROSS-REFERENCE TO RELATED APPLICATIONS Not applicable. BACKGROUND OP THE INVENTION 1. Field of the Invention The invention relates to novel compounds that function as protein tyrosine kinase inhibitors. More particularly, the invention relates to novel arylamide and hetereoarylamide compounds that

Inhibitors of c-fms kinase

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BACKGROUND OF THE INVENTION The invention relates to novel compounds that function as protein tyrosine kinase inhibitors. More particularly, the invention relates to novel compounds that function as inhibitors of c-fms kinase. Protein kinases are enzymes that serve as key components of signal

Inhibitors of c-fms kinase

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BACKGROUND OF THE INVENTION The invention relates to novel compounds that function as protein tyrosine kinase inhibitors. More particularly, the invention relates to novel compounds that function as inhibitors of c-fms kinase. Protein kinases are enzymes that serve as key components of signal

Inhibitors of c-fms kinase

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BACKGROUND OF THE INVENTION The invention relates to novel compounds that function as protein tyrosine kinase inhibitors. More particularly, the invention relates to novel compounds that function as inhibitors of c-fms kinase. Protein kinases are enzymes that serve as key components of signal

Inhibitors of c-fms kinase

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BACKGROUND OF THE INVENTION The invention relates to novel compounds that function as protein tyrosine kinase inhibitors. More particularly, the invention relates to novel compounds that function as inhibitors of c-fms kinase. Protein kinases are enzymes that serve as key components of signal

Inhibitors of C-FMS kinase

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BACKGROUND OF THE INVENTION The invention relates to novel compounds that function as protein tyrosine kinase inhibitors. More particularly, the invention relates to novel compounds that function as inhibitors of c-fms kinase. Protein kinases are enzymes that serve as key components of signal

Inhibitors of c-fms kinase

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BACKGROUND OF THE INVENTION The invention relates to novel compounds that function as protein tyrosine kinase inhibitors. More particularly, the invention relates to novel compounds that function as inhibitors of c-fms kinase. Protein kinases are enzymes that serve as key components of signal

Inhibitors of C-FMS kinase

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SEQUENCE LISTING The instant application contains a Sequence Listing which has been submitted in ASCII format via EFS-Web and is hereby incorporated by reference in its entirety. Said ASCII copy, created on Jul. 23, 2013, is named PRD2659USDIV3_SL.txt and is 825 bytes in size. BACKGROUND OF THE

Inhibitors of c-fms kinase

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BACKGROUND OF THE INVENTION The invention relates to novel compounds that function as protein tyrosine kinase inhibitors. More particularly, the invention relates to novel compounds that function as inhibitors of c-fms kinase. Protein kinases are enzymes that serve as key components of signal

Inhibitors of c-fms kinase

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BACKGROUND OF THE INVENTION The invention relates to novel compounds that function as protein tyrosine kinase inhibitors. More particularly, the invention relates to novel compounds that function as inhibitors of c-fms kinase. Protein kinases are enzymes that serve as key components of signal

Inhibitors of c-fms kinase

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BACKGROUND OF THE INVENTION The invention relates to novel compounds that function as protein tyrosine kinase inhibitors. More particularly, the invention relates to novel compounds that function as inhibitors of c-fms kinase. Protein kinases are enzymes that serve as key components of signal

Inhibitors of c-fms kinase

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BACKGROUND OF THE INVENTION The invention relates to novel compounds that function as protein tyrosine kinase inhibitors. More particularly, the invention relates to novel compounds that function as inhibitors of c-fms kinase. Protein kinases are enzymes that serve as key components of signal

Inhibitors of c-fms kinase

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BACKGROUND OF THE INVENTION The invention relates to novel compounds that function as protein tyrosine kinase inhibitors. More particularly, the invention relates to novel compounds that function as inhibitors of c-fms kinase. Protein kinases are enzymes that serve as key components of signal

Inhibitors of c-fms kinase

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BACKGROUND OF THE INVENTION The invention relates to novel compounds that function as protein tyrosine kinase inhibitors. More particularly, the invention relates to novel compounds that function as inhibitors of c-fms kinase. Protein kinases are enzymes that serve as key components of signal
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