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Rupture of spleen in a mechanically ventilated patient with falciparum malaria admitted with pulmonary edema.

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Rupture of the spleen in malaria may constitute a diagnostic challenge to many clinicians particularly in non-endemic areas where experience with malaria is limited. Our aim is to increase the awareness among clinicians from non-endemic areas of serious malarial complications. We present a young

Eperythrozoon infection in young bulls with scrotal and hindlimb edema, a herd outbreak.

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Young (9 to 10 mo) Aberdeen-Angus bulls (n = 5) in excellent body condition and pastured with approximately 35 other bulls of similar age on a farm in southeastern Alabama had fever, harsh pulmonary sounds, increased respiratory rate and variable amounts of hindlimb and scrotal edema. Bulls had mild

Noncardiogenic pulmonary edema and pulmonary fibrosis in falciparum malaria.

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Noncardiogenic pulmonary edema is an uncommon but serious complication of falciparum malaria. A case of fatal noncardiogenic pulmonary edema complicating falciparum malaria is presented in which the unfavorable outcome resulted from rapidly developing pulmonary fibrosis, documented through open-lung

Pulmonary edema in cerebral malaria patients in Thailand.

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Pulmonary edema is a serious complication of falciparum malaria that usually occurs in association with cerebral malaria, acute renal failure, high parasitemias, or delayed antimalarial treatment. From 1993 to 1996, 120 adult patients admitted to the intensive care unit of the Bangkok Hospital for

Endothelial cell changes are associated with pulmonary edema and respiratory distress in mice infected with the WA1 human Babesia parasite.

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A C3H/HeN mouse model was established to study the pathogenesis of the human babesial parasites, WA1 and Babesia microti. To evaluate the course of parasitemia and the associated lesions, mice were inoculated intraperitoneally with either WA1-infected, B. microti-infected, or uninfected hamster red

Pulmonary edema in severe falciparum malaria. Hemodynamic study and clinicophysiologic correlation.

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This study was performed to extend the knowledge of the pathogenesis of PE in severe falciparum malaria. Sequential hemodynamic studies were conducted in 13 patients with severe falciparum malaria. Seven patients developed PE, while the other six patients had NPE. Two patients died, one in each

Adult cerebral malaria: prognostic importance of imaging findings and correlation with postmortem findings.

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OBJECTIVE To correlate imaging abnormalities, clinical features, and postmortem findings in patients with proved cerebral malaria. METHODS Twenty-one patients aged 17-50 years with cerebral malaria consented to undergo transverse nonenhanced (10-mm sections) and contrast material-enhanced (8-mm

[Behavior of a Trypanosoma brucei strain (STIB 348C) in mice. 3. Histopathological findings in the terminal stage of infection].

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Histopathological findings in the terminal stage of the infection of mice and rats with different variants of the Trypanosoma brucei brucei stock are described. Mice infected with mild variants showed after 12-149 days intense trypanosome colonization of the interstitial connective tissue,

Pathogenic role of P-selectin in experimental cerebral malaria: importance of the endothelial compartment.

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P-selectin is a leukocyte adhesion receptor expressed on the surface of activated platelets and endothelial cells. Its role in the pathogenesis of cerebral malaria was explored in a murine model of cerebral malaria. Infection of mice with Plasmodium berghei ANKA led to P-selectin up-regulation in

Comparative virulence of three Trypanosoma evansi isolates from water buffaloes in the Philippines.

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The virulence of three Trypanosoma evansi isolates in Luzon, Visayas and Mindanao water buffaloes was compared determining the mortality rate, parasitemia level, clinical signs, and lesions on mice. A total of 51 inbred Balb/c mice (5-6 weeks old) were used and divided into two sets. Set A had three

Parasitological, serological, and clinical studies of Wuchereria bancrofti in Limbe, Haiti.

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A survey for Wuchereria bancrofti in Limbe, Haiti (est. pop. = 10,500) revealed that 17% (231/1,450) had a patent infection. Nearly half of those surveyed harbored fewer than 10 microfilariae (mf) per 20 mm3 of finger-prick blood; the median mf density for females and males was 12.4 and 9.5,

The natural killer complex regulates severe malarial pathogenesis and influences acquired immune responses to Plasmodium berghei ANKA.

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The natural killer complex (NKC) is a genetic region of highly linked genes encoding several receptors involved in the control of NK cell function. The NKC is highly polymorphic, and allelic variability of various NKC loci has been demonstrated in inbred mice. Making use of BALB.B6-Cmv1r congenic

Are maternal re-infections with Trypanosoma cruzi associated with higher morbidity and mortality of congenital Chagas disease?

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BACKGROUND Comparing two surveys performed in Bolivia in 1992-1994 and 1999-2001, we reported a significant decrease in the proportions of severe and mortal forms of congenital Chagas disease. This might be due to a reduction of vectorial density (VD) in maternal residence area, raising the question

Clinical, serologic, and pathologic changes in calves with experimentally induced Trypanosoma brucei infection.

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In 7 calves inoculated with Trypanosoma brucei and observed for 105 days, the minimal clinical signs were occasional lethargic periods associated with parasitemia. Rectal temperatures increased by postinoculation day (pid), 10, remained moderately high until PID 50 to 60, and then returned to base

An unusual adhesion between red-cells and platelets in falciparum malaria.

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A Thai female patient infected with P. falciparum had 80 per cent P. falciparum infected red cells at ring stage in the peripheral blood smear. The complications included anemia, thrombocytopenia, acute renal failure and pulmonary edema. A marked decrease in platelets number, low hemoglobin, low

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