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[Esophageal pH-metry. Evaluation of prescriptions at the Robert-Debré Hospital (Paris)].

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OBJECTIVE To record orders for esophageal pH-metry at the Robert-Debré hospital in Paris and to assess the quality and pertinence on the order. METHODS A prospective survey of all children who underwent pH-metry during the month of February 1996 was conducted. There were 11 children included in the

[Poisoning with Jatropha curcas: 24 cases reported to Paris and Marseille Poisons Centers].

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Jatropha curcas L. is an inedible plant belonging to the Euphorbiaceae family that is growing in subtropical zones of all continents. We report a series of 24 cases of poisoning with J. curcas seeds or fruits reported to poison centers in Paris and Marseille between December 2000 and June 2014.

Gastrointestinal tuberculosis: 17 cases collected in 4 hospitals in the northeastern suburb of Paris.

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Gastrointestinal tuberculosis is a rare form of extrapulmonary tuberculosis and its diagnosis can be difficult. OBJECTIVE To analyze the diagnostic and therapeutic characteristics of gastrointestinal tuberculosis. METHODS Retrospective study from 17 cases collected in 4 hospitals in Seine

[Exposure to liquid detergent capsules: a study of the cases reported to the Paris Poison Center, 2011-2012].

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OBJECTIVE To evaluate the toxicity of liquid detergent capsules for children. METHODS Analysis of 684 consecutive cases from the Paris Poison Center (2011-2012). RESULTS Most enquiries (97 %) concerned children 5 years of age or younger. The main circumstances of exposure were ingestion alone (72.4

Surveillance to estimate the burden of rotavirus gastroenteritis in children aged less than 3 years attending day care centers in Paris, France.

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Between December 2006-May 2007, 371 children aged <3 years attending 15 day care centers (DCCs) in Paris, France were actively followed for acute gastroenteritis [GE; diarrhea (≥3 loose stools/24 hours with or without vomiting) for <14 days] and outbreaks of acute GE (≥3 cases in a DCC with onset

[Tolerance and efficacy of atovaquone-proguanil for the treatment of paediatric imported Plasmodium falciparum malaria in France: clinical practice in a university hospital in Paris].

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Only few drugs for uncomplicated Plasmodium falciparum malaria are available in children. Atovaquone-proguanil is a recent antimalarial drug licensed in France for the uncomplicated P. falciparum malaria in adults. Few paediatric studies have evaluated atovaquone-proguanil in children for

Ipecacuanha: the South American vomiting root.

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The story of ipecacuanha, derived from the plant Cephaelis, is a fascinating one. It was discovered in Brazil in the 1600s and then transported to Paris in the latter part of the same century. It was used there by the physician Helvetius on various members of the French royal court to treat the flux

The association of temperament with nausea and vomiting during early pregnancy.

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ABSRACT We aimed to investigate the relationship between affective temperaments and the severity of nausea and vomiting symptoms in early pregnancy (NVP). The pregnant women who did (n = 187) or did not report (n = 71) any nausea and vomiting at three consecutive assessments with the

Oral vinorelbine (Navelbine) in the treatment of advanced non-small cell lung cancer: a preliminary report.

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Vinorelbine (Navelbine; Burroughs Wellcome Co, Research Triangle Park, NC; Pierre Fabre Médicament, Paris, France) is a novel semisynthetic vinca alkaloid with antitumor activity in non-small cell lung cancer. An oral preparation of this drug is under investigation and was tested in a multicenter

Acute fluvoxamine poisoning.

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A total of 221 cases of deliberate acute overdose with fluvoxamine reported to the Paris Poison Centre, and 78 cases collected by the International Drug Safety Department of Duphar BV were analysed. Other agents, mainly benzodiazepines, neuroleptics, other antidepressants and alcohol, were also

Intraarterial infusion of 5-fluoro-2-deoxyuridine-C8 dissolved in a lymphographic agent in malignant liver tumors. A preliminary report.

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The drug 5-fluoro-2-deoxyuridine-C8 (FUdR-C8), one of the lipophilic prodrugs of FUdR, was dissolved in an oily lymphographic agent (Lipiodol Ultra Fluid, Andre Gelbe Laboratory, Paris, France; Ethiodol, Savage Laboratories, Melville, NY) and used for the intraarterial treatment of malignant liver

Oral vinorelbine (Navelbine) in the treatment of advanced breast cancer.

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Vinorelbine (Navelbine; Burroughs Wellcome Co, Research Triangle Park, NC; Pierre Fabre Médicament, Paris, France) has been formulated as a liquid-filled, soft gelatin capsule. Pharmacokinetic studies of this agent indicate that it has a large volume of distribution, a long terminal half-life, and a

Rotavirus carriage, asymptomatic infection, and disease in the first two years of life. I. Virus shedding.

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From September 1979 to July 1980 inclusive, rotaviruses were prospectively detected by electron microscopy (EM) and ELISA in 82 (29%) of 283 children under two years of age who were admitted to a general pediatric ward in Paris. Rotavirus was found in 43 (36%) of 119 children with diarrhea and in 40

Severe gastrointestinal toxicity of MEK inhibitors.

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Gastrointestinal toxicities of MEK inhibitors in melanoma patients are frequent. In clinical trials, the most common digestive adverse events were nausea, vomiting, and diarrhoea. However, severe toxicities such as colitis and gastrointestinal perforation, some with fatal outcomes, have been

Combined doxorubicin/vinorelbine (Navelbine) therapy in the treatment of advanced breast cancer.

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A multicenter US study of the combination of doxorubicin (50 mg/m2 day 1) and vinorelbine (Navelbine; Burroughs Wellcome Co, Research Triangle Park, NC; Pierre Fabre Médicament, Paris, France) (25 mg/m2 days 1 and 8) every 21 days examined the effects of this regimen as first-line chemotherapy in

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