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Hepato-gastroenterology

Preoperative bone mineral density in gastric cancer patients.

Články môžu prekladať iba registrovaní používatelia
Prihlásiť Registrácia
Odkaz sa uloží do schránky
Takao Katsube
Minoru Murayama
Kentaro Yamaguchi
Akira Miyaki
Noriyuki Isohata
Shinichi Asaka
Schunichi Shiozawa
Kazuhiko Yoshimatsu
Takeshi Shimakawa
Yoshihiko Naritaka

Kľúčové slová

Abstrakt

OBJECTIVE

It has been reported that there is a high rate of bone mineral density (BMD) loss after gastrectomy for gastric cancer. To clarify the course of postoperative BMD loss, it is necessary to precisely determine the preoperative BMD of gastric cancer patients.

METHODS

From October 2005 through September 2008, preoperative BMD was measured in 91 patients (59 males and 32 females, mean age of the patients was 67.3 years) who underwent gastrectomy for gastric cancer. Then, the percentage of the subject's BMD divided by the BMD of young adult mean (YAM) (% of YAM) was obtained for each subject and the incidence of osteoporosis as well as the relationship between % of YAM and the patient's clinico-pathological factors or biochemical parameters was examined.

RESULTS

The incidence of osteoporosis was 15.4%. There is a correlation between BMD in preoperative gastric cancer patients and serum albumin levels, and BMD decreases further in the elderly and individuals with a BMI lower than 18.5.

CONCLUSIONS

From the viewpoint of osteoporosis prevention, this suggests the importance of nutritional management for elderly gastric cancer patients with associated nutritional disorder.

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