Journal of Pharmacy and Bioallied Sciences 2019-May
Preparation of Mouthwash and Gel from Rosa damascena Mill and Evaluating Its Effectiveness-An In Vivo Analysis.
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Background
Rosa damascena Mill, commonly known as Damascus rose and garland rose, belongs to Rosaceae family, which has around 200 different types of rose species. R. damascena Mill is famous for its fragrance and beauty, and hence it is highly cultivated all over the world. In addition, this plant is also used for its medicinal properties.Materials and Methods
At the JSS College of Pharmacy, Ooty, the oil of R. damacena Mill was converted into mouth wash and gel. To evaluate the effectiveness of the prepared rose gel and mouthwash, 24 Wister and 24 Albino rats were subjected to acetic acid induced writhing, hot plate method, and Carragennin induced paw edema test.Results
Acetic acid induced writhing in mice and hot plate method were carried out. Both methods proved presence of analgesic activity, and Carragennin induced paw edema test showed the anti-inflammatory property of R. damascena mill.Conclusion
These two in vivo studies proved that the presence of analgesic and anti-inflammatory properties in prepared R. damascena mill mouth wash and gel.