Consecutive patients presenting to the ED with either a suspected or documented infection in which blood samples were taken during routine. An extra blood sample was taken to measure PCT & MR-proADM using the Samsung IB10 point of care assay.

Sepsis

It is an observational study. The only intervention was the measure of MR-proADM, but no clinical decision was made based on its value, since the physician attending the patient did´n know the value of MR-proADM

Measurement of MR-proADM

Hospital Universitario General de Alicante

Hospital Universitario de Bellvitge

Hospita Clínico San Carlos

Assessment of Disease Severity, Progression and Treatment in Infected Patients Presenting to the Emergency Department

ADAPTED: Assessment of Disease Severity, Progression and Treatment in Infected Patients Presenting to the Emergency Department

Intensive care admission of the attended patient

Length of time from initial presentation at the ED to the first dose of antibiotics being administered.

Composite endpoint consisting of infection-related 30-day mortality, ICU admission and a ≥2 point increase in NEWS or SOFA score between presentation and 72 hrs

Juan González-del Castillo

HEAD OF INFECTION DISEASE GROUP OF SPANISH EMERGENCY MEDICINE SOCIETY

Thermo Fisher Scientific

Fatal Outcome

4th Department of Internal Medicine, ATTIKON University Hospital

Proadrenomedullin for Early Risk Assessment in the Emergency Department

A Prospective Clinical Trial of the Efficacy of Mid-regional Proadrenomedullin in the Triage and Multi-dimensional Risk Assessment of Patients Admitted to the Emergency Department

Analysis of a predefined algorithm by MR-proADM cut-off values (<0.75 nmol/L as low risk, 0.75 nmol/L≥ and ≤ 1.5 nmol/L as intermediate risk and >1.5 nmol/L as high-risk) to rule-out the risk of unfavorable outcome.

To analyze a predifined algorithm of MR-proAMD and to evaluate relationship with final diagnosis

To analyze a predifined algorithm of MR-proAMD trying to develop an algorithm for decision-making in real-life

To analyze a predifined algorithm of MR-proAMD trying to answer if it is an independent predictor of final outcome based on multivariate models

acidic peptide/nekróza

Assessment of Disease Severity, Progression and Treatment in Infected Patients Presenting to the Emergency Department

Proadrenomedullin for Early Risk Assessment in the Emergency Department

Diagnostic and Prognostic Value of Serial Procalcitonin (PCT) Measurements in Critically Ill Patients

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