Alkane / zápal

Di-(5-hydroxy-2(5H)-2-oxo-4-furyl)methyl-alpha,omega alkane-dioates and N,N-bis-(5-hydroxy-2(5H)-2-oxo-4-furyl)methyl-alpha,omega-dialkanoic acid amides as anti-inflammatory agents

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BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention is directed to novel substituted di-[5-hydroxy-2(5H)-4-furanonyl]methyl- alkane-dioates and N,N-bis-[5-hydroxy-2(5H)-4-furanonyl]methyl- dialkanoic acid amides which are active as anti-inflammatory agents. The present

Substituted dihydroxy-bis-[5-hydroxy-2(5H)-furanone-4-yl]-alkanes as anti-inflammatory agents

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BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention is directed to novel substituted dihydroxy-bis-[5-hydroxy-2(5H)-furanone-4-yl]-alkanes which are active as anti-inflammatory agents. The present invention is also directed to pharmaceutical compositions which comprise one or

Long-chain alcohols, alkanes, fatty acids and amides in the treatment of burns and viral inhibition

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FIELD OF THE INVENTION This invention relates to therapeutic treatment of viral infections and skin inflammation using long chain fatty acids, long chain alkanes, amides and mono-unsaturated long chain alcohols, particularly by application of therapeutic compositions containing a nonionic surfactant

Alkane diol derivatives as therapeutic agents for the treatment of bone conditions

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This application is the US national phase of international application PCT/GB02/04933 filed in English on 31 Oct. 2002, which designated the US. PCT/GB02/04933 claims priority to GB Application No. 0126157.7 filed 31 Oct. 2001. The entire contents of these applications are incorporated herein by

Dialkyl-phosphinoyl-alkane (Dapa) compounds and compositions for treatment of lower gastrointestinal tract disorders

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CROSS-REFERENCE TO RELATED APPLICATIONS This application is a continuation-in-part of International (PCT) Patent Application No PCT/GB2013/052750, filed Oct. 22, 2013 and International (PCT) Patent Application No PCT/GB2013/052751, filed Oct. 22, 2013, U.S. Ser. No. 14/544,042 filed Nov. 18, 2014,

1-(2-hydroxyaryl)-alkane-1-on-oximes-procedure of preparation and use in pharmaceuticals

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BACKGROUND OF THE INVENTION AND PRIOR ART STATEMENT This invention relates partially to new 1-(2-hydroxyaryl)-alkane-1-on-oximes, processes for their preparation, and their applicability to pharmaceutical preparations. The compounds in their own right and, consequently, the pharmaceutical products

AZA spiro alkane derivatives as inhibitors of metalloproteases

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FIELD OF THE INVENTION The present invention relates to aza spiro alkane compounds which are useful in treating diseases, pathologic conditions and disorders associated with metalloprotease activity, including activity of sheddases and adamalysins (ADAMs). BACKGROUND OF THE INVENTION Most tissues

Aza spiro alkane derivatives as inhibitors of metalloproteases

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FIELD OF THE INVENTION The present invention relates to aza spiro alkane compounds which are useful in treating diseases, pathologic conditions and disorders associated with metalloprotease activity, including activity of sheddases and adamalysins (ADAMs). BACKGROUND OF THE INVENTION Most tissues

Aza spiro alkane derivatives as inhibitors of metalloproteases

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FIELD OF THE INVENTION The present invention relates to aza spiro alkane compounds which are useful in treating diseases, pathologic conditions and disorders associated with metalloprotease activity, including activity of sheddases and adamalysins (ADAMs). BACKGROUND OF THE INVENTION Most tissues

AZA spiro alkane derivatives as inhibitors of metalloproteases

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FIELD OF THE INVENTION The present invention relates to aza spiro alkane compounds which are useful in treating diseases, pathologic conditions and disorders associated with metalloprotease activity, including activity of sheddases and adamalysins (ADAMs). BACKGROUND OF THE INVENTION Most tissues

Aza spiro alkane derivatives as inhibitors of metalloproteases

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FIELD OF THE INVENTION The present invention relates to aza spiro alkane compounds which are useful in treating diseases, pathologic conditions and disorders associated with metalloprotease activity, including activity of sheddases and adamalysins (ADAMs). BACKGROUND OF THE INVENTION Most tissues

Aza spiro alkane derivatives as inhibitors of metalloproteases

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FIELD OF THE INVENTION The present invention relates to aza spiro alkane compounds which are useful in treating diseases, pathologic conditions and disorders associated with metalloprotease activity, including activity of sheddases and adamalysins (ADAMs). BACKGROUND OF THE INVENTION Most tissues

AZA spiro alkane derivatives as inhibitors of metalloproteases

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FIELD OF THE INVENTION The present invention relates to azaspiro alkane compounds which are useful in treating diseases, pathologic conditions and disorders associated with metalloprotease activity, including activity of sheddases and adamalysins (ADAMs). BACKGROUND OF THE INVENTION Most tissues

Bis-heteroaryl alkanes as therapeutic agents

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FIELD OF THE INVENTION This invention relates to compounds which are inhibitors of protein tyrosine phosphatases (PTPases), which are useful for the management, treatment, control, or adjunct treatment of diseases caused by over-activity of PTPases. BACKGROUND OF THE INVENTION The process of protein

Diphenyl substituted alkanes

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FIELD OF THE INVENTION The instant invention involves compounds that inhibit 5-lipoxygenase activating protein (FLAP), compositions containing such compounds and methods of treatment using such compounds for the treatment and prevention of atherosclerosis and related diseases and

alkane/zápal

Di-(5-hydroxy-2(5H)-2-oxo-4-furyl)methyl-alpha,omega alkane-dioates and N,N-bis-(5-hydroxy-2(5H)-2-oxo-4-furyl)methyl-alpha,omega-dialkanoic acid amides as anti-inflammatory agents

Substituted dihydroxy-bis-[5-hydroxy-2(5H)-furanone-4-yl]-alkanes as anti-inflammatory agents

Long-chain alcohols, alkanes, fatty acids and amides in the treatment of burns and viral inhibition

Alkane diol derivatives as therapeutic agents for the treatment of bone conditions

Dialkyl-phosphinoyl-alkane (Dapa) compounds and compositions for treatment of lower gastrointestinal tract disorders

1-(2-hydroxyaryl)-alkane-1-on-oximes-procedure of preparation and use in pharmaceuticals

AZA spiro alkane derivatives as inhibitors of metalloproteases

Aza spiro alkane derivatives as inhibitors of metalloproteases

Aza spiro alkane derivatives as inhibitors of metalloproteases

AZA spiro alkane derivatives as inhibitors of metalloproteases

Aza spiro alkane derivatives as inhibitors of metalloproteases

Aza spiro alkane derivatives as inhibitors of metalloproteases

AZA spiro alkane derivatives as inhibitors of metalloproteases

Bis-heteroaryl alkanes as therapeutic agents

Diphenyl substituted alkanes

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