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Novel 2-thienyloxyacetic acid derivatives, a process for their preparation and pharmaceutical preparations containing them

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DESCRIPTION The invention relates to novel 2-thienyloxyacetic acid derivatives, a process for their preparation and pharmaceutical preparations containing these substances. Substances with an antithrombotic action have already been known for a relatively long time. Thus, for example, acetylsalicylic

Method of treatment and pharmaceutical composition

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The present invention relates to a pharmaceutical composition comprising as active ingredients (i) the AT.sub.1 receptor antagonist (S)-N-(1-carboxy-2-methyl-prop-1-yl)-N-pentanoyl-N-[2'(1H-tetrazol-5-yl)bi phenyl-4-yl-methyl]amine (valsartan) of formula (I) ##STR1## or a pharmaceutically acceptable

Method of treatment and pharmaceutical composition

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The present invention relates to a pharmaceutical composition comprising as active ingredients (i) the AT.sub.1 receptor antagonist (S)-N-(1-carboxy-2-methyl-prop-1-yl)-N-pentanoyl-N-[2'(1H-tetrazol-5-yl)bi phenyl4-yl-methyl]amine (valsartan) of formula (I) ##STR1## or a pharmaceutically acceptable

Pharmaceutical composition with antibody that binds to heat shock protein 27(HSP270) and method for promoting wound healing

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CROSS-REFERENCE TO RELATED APPLICATIONS This application is the U.S. National Stage of International Application No. PCT/KR2011/006065, filed Aug. 18, 2011, which claims priority to and the benefit of Korean Patent Application No. 10-2010-0079857, filed Aug. 18, 2010, which is hereby incorporated by

Methods of treatment and pharmaceutical composition

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BACKGROUND OF THE INVENTION The renin angiotensin system is a complex hormonal system comprised of a large molecular weight precursor, angiotensinogen, two processing enzymes, renin and angiotensin converting enzyme (ACE), and the vasoactive mediator angiotensin II (Ang II). See J. Cardiovasc.

Methods of treatment and pharmaceutical composition

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BACKGROUND OF THE INVENTION The renin angiotensin system is a complex hormonal system comprised of a large molecular weight precursor, angiotensinogen, two processing enzymes, renin and angiotensin converting enzyme (ACE), and the vasoactive mediator angiotensin II (Ang II). See J. Cardiovasc.

Aza-amino acid derivatives (factor Xa inhibitors 15)

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The invention relates to semicarbazides of the general formula I, ##STR2## where: R.sup.1 is --(CH.sub.2).sub.n --NH.sub.2, --CON.dbd.C(NH.sub.2).sub.2, --NHC(.dbd.NH)--NH.sub.2 or --C(.dbd.NH)--NH.sub.2, which can also be monosubstituted by --OH, --OCOOA, --OCOO(CH.sub.2).sub.n N(A).sub.2,

Acylated indanyl amines and their use as pharmaceuticals

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The present invention relates to acylated indanyl amines of the general formula (I), with the definitions of R.sup.1 to R.sup.5 and A and B given below in the text, in any of their stereoisomeric forms or mixtures thereof in any ratio and/or pharmaceutically acceptable salts thereof, and their use

Acylated indanyl amines and their use as pharmaceuticals

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The present invention relates to acylated indanyl amines of the general formula (I), with the definitions of R.sup.1 to R.sup.5 and A and B given below in the text, in any of their stereoisomeric forms or mixtures thereof in any ratio and/or pharmaceutically acceptable salts thereof, and their use

Acylated indanyl amines and their use as pharmaceuticals

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The present invention relates to acylated indanyl amines of the general formula (I), with the definitions of R.sup.1 to R.sup.5 and A and B given below in the text, in any of their stereoisomeric forms or mixtures thereof in any ratio and/or pharmaceutically acceptable salts thereof, and their use

Aromatic ring derivatives

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TECHNICAL FIELD The present invention relates to novel aromatic ring derivatives and specifically to novel aromatic ring derivatives and their pharmaceutically acceptable salts having blood sugar level-depressing activity or PDE5-inhibiting activity. The present invention also relates to

Benzimidazole derivatives

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TECHNICAL FIELD The present invention relates to novel benzimidazole derivatives, and, more precisely, to novel benzimidazole derivatives and their pharmaceutically acceptable salts having blood sugar level-depressing activity or PDE5-inhibiting activity. The present invention also relates to

Benzimidazole compounds

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TECHNICAL FIELD The present invention relates to novel benzimidazole derivatives, and, more precisely, to novel benzimidazole derivatives and their pharmaceutically acceptable salts having blood sugar level-depressing activity or PDE5-inhibiting activity. The present invention also relates to

Endothelin-antagonizing peptide

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FIELD OF THE INVENTION The present invention relates to a novel peptide which has endothelin-antagonizing activity, and an intermediate for its synthesis. The peptide has excellent endothelin-antagonizing activity, and is therefore useful for treatment of hypertension, asthma, cerebral apoplexy,

Soluble guanylate cyclase activators

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BACKGROUND OF THE INVENTION Cyclic GMP is an important intracellular messenger which triggers a multitude of different effects via the modulation of cGMP-dependent protein kinases, phosphodiesterases and ion channels. Examples are the relaxation of smooth muscles, the inhibition of thrombocyte
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