auxin/zhubný nádor

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[Stimulation of induction or inhibition of crown-gall tumor development by RNA-fragments U2. Interference by auxin].

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RNA-fragments U2 obtained by mild degradation with RNase U2 of ribosomal RNA containing A and G nucleotides in excess are capable of exhibiting either a stimulatory effect on the induction of Crown-gall tumors or an inhibitory action on their subsequent development. These different effects are

Tumor formation in Nicotiana: Auxin levels and auxin inhibitors in normal and tumor-prone genotypes.

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Auxin and auxin-inhibitors from acidic ether extracts of normal stem tissue of Nicotiana longiflora, N. debneyi-tabacum, their tumor producing F 1 hybrid and non-tumor and tumor-prone segregants were separated by thin-layer chromatography and measured by an Avena curvature test. A significantly

Flavonoid-related regulation of auxin accumulation in Agrobacterium tumefaciens-induced plant tumors.

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Agrobacterium tumefaciens-induced plant tumors accumulate considerable concentrations of free auxin. To determine possible mechanisms by which high auxin concentrations are maintained, we examined the pattern of auxin and flavonoid distribution in plant tumors. Tumors were induced in transformants

Thin-layer chromatography of auxin and inhibitors in Nicotiana glauca, N. langsdorffii and three of their tumor-forming hybrids.

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Auxin and auxin-inhibitors from acidic ether extracts of normal Nicotiana stem tissues of N. glauca and N. langsdorffii and their tumor-producing 4n, 3n, and 2n-hybrids were separated by thin-layer chromatography. The growth substances were eluted and subjected to an Avena curvature test. A

Neoplastic progression in crown gall in tobacco without elevated auxin levels.

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We have isolated two stable variants from a crown-gall teratoma tissue of tobacco (Nicotiana tabacum L.) transformed by Agrobacterium tumefaciens strain A66, a mutant of the virulent A6 strain containing an insertion sequence in the tumor-inducing (Ti) plasmid at the locus coding for auxin

The phytohormone auxin induces G1 cell-cycle arrest of human tumor cells.

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The plant hormone auxin is the key regulator of plant growth and development. Auxin regulates transcription of plant genes by targeting degradation of transcriptional repressor proteins Aux/IAA. While there are many reports describing its potential to modulate human cell functions, the majority are

Cytokinin/auxin balance in crown gall tumors is regulated by specific loci in the T-DNA.

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Insertion of the transposon Tn5 into the T-region of the octopine Ti plasmid of Agrobacterium tumefaciens gives rise to crown gall tumors having altered morphology. Three loci within the T-DNA that control tumor morphology have been detected [Garfinkel, D. J., Simpson, R. B., Ream, L. W., White, F.

Auxin: its role in genetic tumor induction.

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Seedlings of the tumor-prone amphiploid Nicotiana suaveolens X N. langsdorffii were grown on nutrient medium supplemented with indoleacetic acid (IAA) and scored at regular intervals for the incidence of tumor formation. IAA at 2 x 10(-5)m caused a significant reduction in the rate of tumor

Oxidative activation of indole-3-acetic acids to cytotoxic species- a potential new role for plant auxins in cancer therapy.

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Indole-3-acetic acid (IAA) and some derivatives can be oxidised by horseradish peroxidase (HRP) to cytotoxic species. Upon treatment with IAA/HRP, liposomes undergo lipid peroxidation, strand breaks and adducts are formed in supercoiled plasmid DNA, and mammalian cells in culture lose colony-forming

Studies on the Metabolism of Plant Neoplasms: V. Auxin as a Promoting Agent in the Transformation of Normal to Crown-Gall Tumor Cells.

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Auxin-Kinetin Interaction in Tissue Cultures of Nicotiana Species & Tumor-Conditioned Hybrids.

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Inhibition of tumor induction by auxin in totally debudded Nicotiana glauca x N. langsdorffii.

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[Auxin-autotrophy and chromosome count. Studies of old, spontaneously habituated and crowngall tumor cultures of Nicotiana tabacum from Gautheret's laboratory].

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Characterization of TCTP, the translationally controlled tumor protein, from Arabidopsis thaliana.

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The translationally controlled tumor protein (TCTP) is an important component of the TOR (target of rapamycin) signaling pathway, the major regulator of cell growth in animals and fungi. TCTP acts as the guanine nucleotide exchange factor of the Ras GTPase Rheb that controls TOR activity in

Cleavage of INDOLE-3-ACETIC ACID INDUCIBLE28 mRNA by microRNA847 upregulates auxin signaling to modulate cell proliferation and lateral organ growth in Arabidopsis.

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MicroRNAs function in a range of developmental processes. Here, we demonstrate that miR847 targets the mRNA of the auxin/indole acetic acid (Aux/IAA) repressor-encoding gene IAA28 for cleavage. The rapidly increased accumulation of miR847 in Arabidopsis thaliana coincided with reduced IAA28 mRNA

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