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Specific carbohydrate-binding proteins (lectins) of mammalian tumor cells

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TECHNICAL FIELD OF THE INVENTION This invention relates to carbohydrate-binding proteins (lectins) of mammalian tumor cells which specifically recognize and bind to carbohydrate molecules and to methods of isolating these lectins from mammalian tumor cells. BACKGROUND ART The designation "lectin" is

Bifunctional glycoproteins having a modified carbohydrate complement and their use in tumor-selective therapy

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BACKGROUND OF THE INVENTION 1. Field of the Invention The invention relates to bifunctional glycoproteins having targeting protein and enzyme properties. More particularly, the invention relates to such proteins whose complements of carbohydrate residues have been modified in a manner that enhances

Carbohydrate-containing pan cancer marker

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REFERENCE TO SEQUENCE LISTING SUBMITTED VIA EFS-WEB The entire content of the following electronic submission of the sequence listing via the USPTO EFS-WEB server, as authorized and set forth in MPEP .sctn.1730 II.B.2(a)(C), is incorporated herein by reference in its entirety for all purposes. The

Methods for diagnosis of colon, stomach and pancreatic cancer using antibodies specific for a mucin-type carbohydrate chain

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The present invention relates to a cancer-related pharmaceutical composition containing an antibody capable of recognizing a carbohydrate chain. It has been reported that when a cell is cancerated, a carbohydrate chain which is not observed in a normal cell, can be detected on the surface of the

Antibodies recognizing a carbohydrate containing epitope on CD-43 and CEA expressed on cancer cells and methods using same

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FIELD OF THE INVENTION The present invention relates to novel monoclonal antibodies that recognize a carbohydrate containing epitope on CD43 and carcinoembryonic antigen (CEA) expressed on nonhematopoietic tumor or cancer cells. These antibodies have the property of inducing cell death (e.g.,

Antibodies recognizing a carbohydrate containing epitope on CD-43 and CEA expressed on cancer cells and methods using same

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Production of fucosyl antigens and antibodies for recognizing same determination of cancer associated carbohydrate linkage using same and kit for the determination

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TECHNICAL FIELD The present invention relates to techniques for producing fucosyl antigens and antibodies for recognizing the same, and more particularly to a process for producing carbohydrate antigens containing a specific carbohydrate linkage as a hapten and a process for producing from the

Compositions for and methods of treating and preventing targeting tumor associated carbohydrate antigens

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FIELD OF THE INVENTION The invention relates to vaccines, isolated antibodies, isolated immune cells and methods of making and using the same to treat and prevent breast cancer. BACKGROUND OF THE INVENTION Anti-tumor immune responses are a facet of the tissue-specific autoimmune phenomenon. The

Monoclonal antibodies and vaccine development directed to human cancer-associated antigens by immunization with carbohydrate-carrier conjugates

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Portions of the invention(s) disclosed herein were supported in part by a grant from the National Cancer Institute, Department of Health & Human Services. FIELD OF THE INVENTION The present invention relates to new methods for the production of monoclonal antibodies specific to human

Antibodies recognizing a carbohydrate containing epitope on CD-43 and CEA expressed on cancer cells and methods using same

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FIELD OF THE INVENTION The present invention relates to antibodies (e.g., chimeric and humanized antibodies) that recognize a carbohydrate containing epitope on CD43 and carcinoembryonic antigen (CEA) expressed on nonhematopoietic tumor or cancer cells. These antibodies have the property of inducing

Antibodies recognizing a carbohydrate containing epitope on CD-43 and CEA expressed on cancer cells and methods using same

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Antibodies recognizing a carbohydrate containing epitope on CD-43 and CEA expressed on cancer cells and methods using same

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The content of the following submission on ASCII text file is incorporated herein by reference in its entirety: a computer readable form (CRF) of the Sequence Listing (file name: 606592000401_SequenceListing.txt, date recorded: Dec. 9, 2013, size: 112,933 bytes). FIELD OF THE INVENTION The present

Monoclonal antibodies and vaccine development directed to human cancer-associated antigens by immunization with animal and human and with synthetic carbohydrate-carrier conjugates

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FIELD OF THE INVENTION The present invention relates to new methods for the production of monoclonal antibodies specific to human cancer-associated antigens and to the hybridomas and monoclonal antibodies produced therefrom. More particularly, the present invention relates to new methods for the

Monoclonal antibodies and vaccine development directed to human cancer-associated antigens by immunization with animal and human mucin and with synthetic carbohydrate-carrier conjugates

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Screening for antibodies which bind carbohydrate epitopes of tumor-associated antigens, and uses thereof

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Methods of synthesizing sialosyl Lewis-a and sialosyl Lewis-x oligosaccharides useful in screening of antibodies are described in commonly owned copending applications of Abbas, Diakur and Sugiyama, Ser. No. 07/159,734, filed Feb. 24, 1988 and Ser. No. 07/193,608, filed May 13, 1988. BACKGROUND OF

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