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Injectable, high modulus, and fatigue resistant composite scaffold for load-bearing soft tissue regeneration.

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High modulus, two-phase, bicontinuous scaffolds were prepared by photocross-linking an aqueous suspension of chondrocytes and N-methacrylate glycol chitosan with a hydrolyzable, hydrophobic, acrylated star-copolymer. Two acrylated star-copolymers were examined: poly(ε-caprolactone-co-d,l-lactide)

Cyclic fatigue of hydroxyapatite-coated titanium alloy implant material--effect of crystallinity.

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Titanium alloy (ASTM F-136) rods were coated with hydroxyapatite (HA) of 3 levels of crystallinity, which were determined by X-ray diffraction (XRD) analysis to be 60.5%, 52.8%, and 47.8%. Fourier Transform Infrared (FTIR) spectroscopy analysis showed the removal of the hydroxyl and carbonate groups

Evaluation of the Fatigue Performance and Degradability of Resorbable PLDLLA-TMC Osteofixations.

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The fatigue performance of explanted in-situ degraded osteofixations/osteosyntheses, fabricated from poly (70L-lactide-co-24DL-lactide-6-trimethylane-carbonate or PLDLLA-TMC) copolymer was compared to that of virgin products. The fatigue test was performed on 21 explants retrieved from 12 women and

Effect of soft-segment chemistry on polyurethane biostability during in vitro fatigue loading.

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The effect of soft-segment chemistry on biostability of polyurethane elastomers was studied with a diaphragm-type film specimen under conditions of static and dynamic loading. During testing, the films were exposed to an H(2)O(2)/CoCl(2) solution, which simulated the oxidative component of the in

A Robust Nacre-like Graphene Oxide-Calcium Carbonate Hybrid Mesh with Underwater Superoleophobic Property for Highly Efficient Oil/Water Separation.

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Inspired by the mastoid structure of lotus leaf and robust layered structure of nacre, a novel nacre-like graphene oxide-calcium carbonate (GO-CaCO₃) hybrid mesh with superhydrophilic and underwater superoleophobic property was prepared for the first time, via a facile, economical and

The effect of metabolic alkalosis on central and peripheral mechanisms associated with exercise-induced muscle fatigue in humans.

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UNASSIGNED What is the central question of this study? Does metabolic alkalosis affect central and peripheral mechanisms associated with exercise-induced muscle fatigue in humans? What is the main finding and its importance? Inducing metabolic alkalosis before exercise preserved voluntary

The effect of pH on fatigue during submaximal isometric contractions of the human calf muscle.

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OBJECTIVE This study examined whether changes in pH throughout the physiologic range would have a differential effect on central and peripheral factors associated with fatigue and force production during submaximal lower limb isometric exercise to task failure. METHODS Eight males completed three

Mapping residual organics and carbonate at grain boundaries and the amorphous interphase in mouse incisor enamel.

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Dental enamel has evolved to resist the most grueling conditions of mechanical stress, fatigue, and wear. Adding insult to injury, it is exposed to the frequently corrosive environment of the oral cavity. While its hierarchical structure is unrivaled in its mechanical resilience, heterogeneity in

Extracorporeal "Giant" locking sliding knot in pediatric and neonatal minimally invasive surgery: indications, techniques, and outcomes.

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OBJECTIVE A prospective study to assess the clinical application of extracorporeal "Giant" locking sliding knot (GLSK) in pediatric and neonatal minimally invasive surgery (MIS). METHODS A total of 152 MIS, of various complexities were performed over a 14-month period with more than 1100 GLSKs used

Screening of Fungi for Potential Application of Self-Healing Concrete.

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Concrete is susceptible to cracking owing to drying shrinkage, freeze-thaw cycles, delayed ettringite formation, reinforcement corrosion, creep and fatigue, etc. Continuous inspection and maintenance of concrete infrastructure require onerous labor and high costs. If the damaging cracks can heal by

Extrapyramidal side effect of donepezil hydrochloride in an elderly patient: A case report.

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Alzheimer disease (AD) is a neurodegenerative disease characterized by progressive cognitive dysfunction, which is mainly manifested as memory impairment and a reduced ability to self-care, often accompanied by neuropsychiatric and behavioral disorders. Donepezil is the second drug to

Increased antibiotic release and equivalent biomechanics of a spacer cement without hard radio contrast agents.

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We compared a novel calcium carbonate spacer cement (Copal® spacem) to well-established bone cements. Electron microscopic structure and elution properties of the antibiotics ofloxacin, vancomycin, clindamycin, and gentamicin were examined. A knee wear simulator model for articulating cement spacers

Pilot study of lithium to restore intestinal barrier function in severe graft-versus-host disease.

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Severe intestinal graft-vs-host disease (GVHD) after allogeneic hematopoietic cell transplantation (HCT) causes mucosal ulceration and induces innate and adaptive immune responses that amplify and perpetuate GVHD and the associated barrier dysfunction. Pharmacological agents to target mucosal

Remarkable effect of selegiline (L-deprenyl), a selective monoamine oxidase type-B inhibitor, in a patient with severe refractory depression: a case report.

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A 34-year-old man presented with severe refractory depression. He had failed to respond to various antidepressants, augmentation therapy with lithium carbonate, and modified electroconvulsive therapy. Switching from amoxapine 150 mg/day to selegiline 7.5 mg/day, a selective monoamine oxidase type-B

Cyclic 48-hour unipolar depression.

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This single case study reports on a 74-year-old woman with 48-hour cycles of mood disturbance for 2 years. Every other day she awakened feeling sad with low energy, decreased appetite, fatigue, diminished enjoyment of normal activities, increased irritability, occasional self-deprecatory thoughts,

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