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Anti-aging properties of Dendrobium nobile Lindl.: From molecular mechanisms to potential treatments.

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Dendrobium Nobile Lindl. (DNL) is one of the central herbs in traditional Chinese medicine which mainly distributes in Guizhou, Yunnan, Guangxi and other sub-tropical areas south of the Yangtze River. In the past decades, it has been used to treat tumors, hyperglycemia, hyperlipidemia,

Phenolic Constituents with Antioxidative, Tyrosinase Inhibitory and Anti-aging Activities from Dendrobium loddigesii Rolfe.

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Aqueous ethanol extracts of powdered stems of Dendrobium loddigesii afforded three new phenolics including threo-7-O-ethyl-9-O-(4-hydroxyphenyl)propionyl-guaiacylglycerol (1), (R)-4,5,4'-trihydroxy-3,3',α-trimethoxybibenzyl (2) and (S)-5,5',7-trihydroxy-3',4'-dimethoxyflavanone (3), together with

Dendrobium nobile Lindl Alkaloids Ameliorate Cognitive Dysfunction in Senescence Accelerated SAMP8 Mice by Decreasing Amyloid-β Aggregation and Enhancing Autophagy Activity

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Background: Dendrobium nobile is a well-known traditional Chinese herbal medicine used for age-related diseases. Dendrobium nobile Lindl alkaloid (DNLA) is the active ingredient to improve learning and memory deficits in laboratory

Anti-osmotic and antioxidant activities of gigantol from Dendrobium aurantiacum var. denneanum against cataractogenesis in galactosemic rats.

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BACKGROUND Dendrobium aurantiacum var. denneanumis widespread in southern China, locally known as "Shihu", "Huangcao" or "Fengdou", has long been used in traditional Chinese medicine for antipyretic, immunomodulatory, anti-aging effects and eye benefiting. OBJECTIVE To investigate the effects of

[Study on Influencing Factors for Induction and Proliferation of Protocorm-like Bodies of Dendrobium officinale].

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To improve the protocorms of Dendrobium officinale induction and proliferation growth rate. Dendrobium officinale plumule was selected as experimental material and 1 /2MS + 2% sucrose + 10% banana puree + 0. 8% agar with p H value of 6. 0 was applied as minimal medium. The optimal hormone

Active-oxygen scavenging activity of traditional nourishing-tonic herbal medicines and active constituents of Rhodiola sacra.

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The active-oxygen scavenging activity of 70 traditional herbal medicines used in China and Japan as nourishing tonics were evaluated by electron spin resonance (ESR) technique, in order to evaluate their effectiveness for anti-aging and to search for new active-oxygen scavengers from natural

Modification and application of polysaccharide from traditional Chinese medicine such as Dendrobium officinale.

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Polysaccharides have various biological activities, such as antioxidant, anti-tumor, antiviral, anti-aging, anti-inflammatory, anti-radiation, hypoglycemic and lipid lowering, immune regulation, etc. Although many polysaccharides have been proved to have various biological activities, in the

Effect of Dendrobium officinale on D-galactose-induced aging mice.

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OBJECTIVE To examine the effect of Dendrobium officinale (DO) on D-galactose-induced aging mice. METHODS Aging mice was induced by D-galactose at 0.125 g/kg for 10 weeks through subcutaneous injection except for the negative control group. After 10 days, according to complete random design, the

Dendrobium alkaloids decrease Aβ by regulating α- and β-secretases in hippocampal neurons of SD rats.

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Background

Alzheimer's disease (AD) is the primary cause of dementia in the elderly. The imbalance between production and clearance of amyloid β (Aβ) is a very early, often initiating factor in AD. Dendrobium nobile Lindl. alkaloids (DNLA) extracted from a Chinese

Dendrobium nobile Lindl alkaloid and metformin ameliorate cognitive dysfunction in senescence-accelerated mice via suppression of endoplasmic reticulum stress.

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The senescence-accelerated mouse prone 8 (SAMP8) mice have many pathological features of Alzheimer's disease (AD) with aging. We previously reported that Dendrobium nobile Lindl alkaloid (DNLA) effectively improved cognitive deficits in multiple Alzheimer's disease (AD) models. This study further

Dendrobium officinalis Flower Improves Learning and Reduces Memory Impairment by Mediating Antioxidant Effect and Balancing the Release of Neurotransmitters in Senescent Rats.

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The Dendrobium officinalis flower (DOF) is popular in China due to common belief in its anti-aging properties and positive effects on "nourish yin". However, there have been relatively few confirmatory pharmacological experiments conducted to date. The aim of this work was to

Diversity and taxonomy of endophytic xylariaceous fungi from medicinal plants of Dendrobium (Orchidaceae).

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Dendrobium spp. are traditional Chinese medicinal plants, and the main effective ingredients (polysaccharides and alkaloids) have pharmacologic effects on gastritis infection, cancer, and anti-aging. Previously, we confirmed endophytic xylariaceous fungi as the dominant fungi in several Dendrobium

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