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Strana 1 od 524 výsledky
Preparation, statistical optimization, in vitro characterization, and in vivo pharmacological evaluation of solid lipid nanoparticles encapsulating propolis flavonoids: a novel treatment for skin edema
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Propolis is a natural resinous product and exerts anti-inflammatory properties. The aim of this study is formulation and characterization of solid lipid nanoparticles (SLNs) encapsulating propolis flavonoids (PFs), intended for topical treatment of skin edema. The nanoparticles were prepared and
Clinical efficacy of micronized purified flavonoid fraction (MPFF) in edema.
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Swelling is one of the most frequent complaints of patients in daily clinical practice; leg edema is its objective confirmation. It can be associated with several diseases. Micronized purified flavonoid fraction (MPFF) is a phlebotropic drug commonly used to treat the signs and symptoms associated
Effect of Terpenoids and Flavonoids Isolated from Baccharis conferta Kunth on TPA-Induced Ear Edema in Mice.
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In this study, we isolated from the aerial parts of Baccharis conferta Kunth (i) a new neoclerodane, denominated "bacchofertone"; (ii) four known terpenes: schensianol A, bacchofertin, kingidiol and oleanolic acid; and (iii) two flavonoids: cirsimaritin and hispidulin. All
Long-term follow-up of oral administration of flavonoids, Centella asiatica and Melilotus, for diabetic cystoid macular edema without macular thickening.
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OBJECTIVE
To evaluate long-term follow-up of the orally administered combination of flavonoids with Centella asiatica and Melilotus for treatment of diabetic cystoid macular edema (CME) without macular thickening.
METHODS
Seventy consecutive patients with type 2 diabetes and CME without macular
Combination of flavonoids with Centella asiatica and Melilotus for diabetic cystoid macular edema without macular thickening.
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OBJECTIVE
The purpose of this study was to evaluate the orally administered combination of flavonoids desmin and troxerutin with Centella asiatica and Melilotus for the treatment of diabetic cystoid macular edema (CME) without macular thickening.
METHODS
In this prospective, interventional,
Isolation of two flavonoids from Tanacetum microphyllum as PMA-induced ear edema inhibitors.
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The CH2Cl2 extract of Tanacetum microphyllum exhibited antiinflammatory activity on PMA-mouse ear model. Two antiinflammatory flavonoids, 5,7-dihydroxy-3,6,4'-trimethoxyflavone (santin) (1) and 5,7-dihydroxy-3,4'-dimethoxyflavone (ermanin) (2), were isolated.
[On the effect of aescin and flavonoid complex from horse chestnut on inflammatory edema].
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The fine structure of different types of experimental edemas for testing the effect of vasoactive drugs demonstrated with a flavonoid.
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Influence of flavonoids on capillary permeability, carrageenin edema and histamine and PGE2 spasms.
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Bioflavonoids from propolis and 6-halogenated flavanones were tested with respect to their effects on increased capillary permeability and to their antiinflammatory and antispasmodic actions, respectively. The 5,7,8-trimethoxy- and 6-fluorflavanone seem to be the best compounds tested.
Understanding lower leg volume measurements used in clinical studies focused on venous leg edema.
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The aim of this review was to discuss the different techniques of leg edema measurement that have been used in clinical trials to help determine the most appropriate method of assessment and quantification for use in future research. Venoactive drugs such as micronized purified flavonoid fraction
Effects of various flavonoids isolated from Scutellaria baicalensis roots on skin damage in acute UVB-irradiated hairless mice.
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OBJECTIVE
Solar ultraviolet (UV) radiation causes skin damage including increasing skin thickness, edema and flush. Scutellaria baicalensis roots have been traditionally used as a remedy for allergic inflammatory diseases in China and Japan. In this study, we examined the effects of four flavonoids
Micronized purified flavonoid fraction and the treatment of chronic venous insufficiency: microcirculatory mechanisms.
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The standard treatments for venous diseases of the lower limb include compression bandaging and stockings as well as surgical removal of varicose veins. There is a number of conditions in which these conventional treatments are ineffective, particularly in the management of leg ulceration. Drug
[Chuju total flavonoids control the SFRP4 expression in Wnt pathway in rheumatoid arthritis model rats].
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OBJECTIVE
To determine the effect of Chuju total flavonoids (CJTF) on the secreted frizzledrelated protein 4 (SFRP4) expression in Wnt pathway in rheumatoid arthritis (RA) model rats.
METHODS
The role of CJTF in the treatment of RA model rats was evaluated by rat arthritis score and paw edema score.
The flavonoid-enriched extract from the root of Smilax china L. inhibits inflammatory responses via the TLR-4-mediated signaling pathway.
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Micronized purified flavonoid fraction (MPFF): a review of its pharmacological effects, therapeutic efficacy and benefits in the management of chronic venous insufficiency.
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Initially, the progression of chronic venous insufficiency is related to venous hypertension. The earliest complaints or symptoms, as well as vessel wall deterioration, valve restructuring, and, eventually, varicose veins, result not only from elevation of pressure, but also from a cascade of
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