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V.A. Cooperative Study on antiplatelet agents in diabetic patients after amputation for gangrene: III. Definitions and review of design and baseline characteristics.

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This report summarizes the major design features, methods, and baseline characteristics of patients enrolled in a Veterans Administration Cooperative Study. In eleven V.A. centers, 231 male diabetic patients who had either a recent amputation for gangrene (N = 207) or active gangrene (N = 24) were

Association between atherogenic dyslipidemia and fournier's gangrene

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Objective: We aimed to determine whether atherogenic dyslipidemia is associated with the disease and morbidity in our patients treated for Fournier's gangrene (FG). Methods:

Risk factors, ethnic differences and mortality associated with lower-extremity gangrene and amputation in diabetes. The WHO Multinational Study of Vascular Disease in Diabetes.

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OBJECTIVE We aimed to examine geographic differences, risk factors and mortality associated with amputation. METHODS Data from 10 of the original 14 centres of the WHO Multinational Study of Vascular Disease in Diabetes were used. This included 3443 men and women aged 35 to 55 years at

Association of differing dietary, metabolic, and clinical risk factors with macrovascular complications of diabetes: a prevalence study of 503 Mexican type II diabetic subjects. I.

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Macrovascular and microvascular complications of diabetes may be associated with different environmental factors. To investigate this further, a prevalence study of 503 Mexican type II diabetic subjects was carried out while their patterns of nutrition were constrained by government food subsidies.

[Hyperlipoproteinemia, a factor of severity in acute pancreatitis].

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The authors make a retrospective analysis of 95 cases of acute pancreatitis hospitalized between 1975 and 1979. In 3,8% of all the cases the acute pancreatitis was associated with hyperlipoproteinemia. The study of the 4 patients involved revealed the primary origin of hyperlipoproteinemia as a

Daily insulin dose as a predictor of macrovascular disease in insulin treated non-insulin-dependent diabetics.

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In the longitudinal Schwabing study, unselected insulin-treated diabetic patients were followed for major vascular complication (MVC) (stroke, myocardial infarction, gangrene) and asymptomatic, early detectable peripheral vascular disease (PVD). In the group of insulin-treated NIDDM multiple

Lipoprotein(a) in diabetes mellitus.

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Epidemiologic studies have identified lipoprotein(a) (Lp(a)) as an independent risk factor for atherosclerosis, mainly for coronary heart disease. Atherosclerosis is the most common cause of death in diabetic patients, but there is little information available concerning the importance of Lp(a) in

Anti-thrombotic and anti-atherogenic action of eicosapentaenoic acid.

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Effects of dietary supplementation with highly purified EPA (1.8-2.7 g/day) for 16 weeks on platelet and red blood cell function and serum lipids concentration were investigated in patients with various thrombotic diseases. Decreases in platelet aggregation, thromboxane formation in platelets,

Risk factors in patients with ischaemic rest pain of the lower limbs.

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One hundred and three consecutive out-patients with ischaemic rest pain were studied. There were 77 men and 26 women with a mean (s.d.) age of 71 (10) years. Thirty-six (35.0%) patients had rest pain alone, 41 (39.8%) in association with an ischaemic ulcer and 26 (25.2%) with digital gangrene. A

Plasma lipid profiles and vascular disease in type 2 (non-insulin dependent) Nigerian diabetic patients.

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Although ischaemic vascular disease is uncommon in Nigerians (diabetic and nondiabetic), foot gangrene of vascular origin still causes considerable morbidity in Nigerian diabetics. One known cause of vascular disease is lipid abnormalities. We therefore measured plasma lipid levels in diabetic

Preventing diabetic foot problems.

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Complications of diabetic foot disease may be prevented through regular office followup that includes inspection of the feet and patient education. Peripheral vascular disease and neuropathy are the pathophysiological factors underlying the development of ulcers and gangrene. Evaluation should

Prevalence of Complications and Clinical Audit of Management of Type 2 Diabetes Mellitus: A Prospective Hospital Based Study.

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BACKGROUND Management of type 2 diabetes mellitus (DM) needs multi factorial risk reduction strategies like weight reduction, blood pressure (BP) control and lipid profile regulation, along with glycaemic control. These strategies should be implemented very early in the course of the disease to

[Prostacyclin and pentoxifylline in the treatment of patients with inoperable occlusions of the peripheral arteries of the lower extremities].

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BACKGROUND The treatment of inoperable patients in terminal stages of chronic arterial occlusive disease is difficult and associated with high incidence of limb amputations and lethal outcomes [1]. Prostacyclin (Pgl2) is a strong vasodilator and the most potent endogenous platelet aggregation

Five-year incidence of major macrovascular complications in diabetes mellitus.

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The incidence of macrovascular morbidity and mortality in diabetics is high. At the end of a five-year observation period in the Schwabing Study 138 (26.5%) out of 542 reexamined diabetics suffered from a cardiovascular death, gangrene or myocardial infarction. Univariate and multiple logistic

A survey study on diabetes management and complication status in primary care setting in Thailand.

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OBJECTIVE Healthcare service in Thailand is stratified into three levels with different facilities of care. This cross-sectional survey study described diabetes management, diabetes control, and late complication status among patients managed in urban primary health care

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