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Strana 1 od 67 výsledky
Overweight, obesity and height as risk factors for meningioma, glioma, pituitary adenoma and nerve sheath tumor: a large population-based prospective cohort study.
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BACKGROUND
In 2016, the International Agency for Research on Cancer (IARC) has announced that avoiding body fatness (i.e. overweight and obesity) contributes to prevent meningioma occurrence, but considered the available evidence for glioma inadequate. The association of body fatness with other CNS
Type 2 diabetes mellitus and obesity are independent risk factors for poor outcome in patients with high-grade glioma.
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Type 2 diabetes mellitus (DM) and obesity are known risk factors for poor outcomes in patients with systemic malignancies but are not well-studied in the brain tumor population. In this study we asked if type 2 DM and elevated body mass index (BMI) are independent risk factors for poor prognosis in
Obesity and Risk for Brain/CNS Tumors, Gliomas and Meningiomas: A Meta-Analysis.
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OBJECTIVE
This meta-analysis aims to examine the association between being overweight/obese and risk of meningiomas and gliomas as well as overall brain/central nervous system (CNS) tumors.
METHODS
Potentially eligible publications were sought in PubMed up to June 30, 2014. Random-effects
Influence of obesity-related risk factors in the aetiology of glioma.
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BACKGROUND
Obesity and related factors have been implicated as possible aetiological factors for the development of glioma in epidemiological observation studies. We used genetic markers in a Mendelian randomisation framework to examine whether obesity-related traits influence glioma risk. This
Extensive gliomas of visual tract in a patient of neurofibromatosis-I.
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Although bilateral optic nerve gliomas are commonly found in patients with neurofibromatosis I, extensive gliomas involving the entire visual tracts, bilaterally are relatively rare. Usually the optic radiations are spared. We report a case of a 2-year-old child with extensive disease of bilateral
Glioma progression in diabesity.
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Diabetes mellitus, obesity, and cancer are diseases that in recent years have caused a large number of deaths worldwide, so have been in the front line of biomedical research. On the other hand, obesity is a risk factor for several types of cancer and type 2 diabetes mellitus. The metabolic disorder
Prevalence of obesity, hyperlipemia and insulin resistance in children with suprasellar brain tumors.
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Weight gain is a common sequela of suprasellar tumors, referred to as hypothalamic obesity. We undertook an evaluation of obesity and metabolic aberrations among patients treated at our institute. During the 12 mo from Apr. 2005, 23 patients (10 males and 13 females) with remitted suprasellar tumors
Snoring associated with Ondine's curse in a patient with brainstem glioma.
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Ondine's curse is an uncommon type of sleep apnea syndrome characterized by failure of automatic respiration. We present an adult patient with brainstem glioma who presented with snoring and Ondine's curse as the only symptoms.
METHODS
A 52-year-old female was brought to the hospital by a fellow
Faithful animal modelling of human glioma by using primary initiating cells and its implications for radiosensitization therapy [ARRIVE 1].
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It has been reported that the ATM kinase inhibitor KU60019 preferentially radiosensitizes orthotopic high grade gliomas (HGG) driven by established U87 and U1242 cell lines bearing specific TP53 mutations. We wished to determine whether those results could be extended to tumors driven by primary
Malignant glioma as a secondary malignant neoplasm after radiation therapy for craniopharyngioma: report of a case and review of reported cases.
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BACKGROUND
The development of a secondary neoplasm in childhood cancer survivors attains growing importance due to the reported excellent survival and therefore the long exposure to potentially carcinogenic effects of treatment.
METHODS
We report a 14-year-old girl in whom a large craniopharyngioma
[Optic chiasm glioma in children: Endocrine disorders in 14 cases].
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OBJECTIVE
To describe the frequency of endocrine disorders in children with optic chiasm glioma and analyze related factors.
METHODS
Review of medical records by collecting sex, age, history of neurofibromatosis, clinical presentation, treatment of tumour, and presence of endocrine abnormalities.
[Benign cerebral gliomas. Clinical and radiological characteristics].
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Between July 1988 and July 1990, 42 patients with low-grade gliomas of the cerebrum were treated in our department. Their age ranged from six to 72, there were 27 males and 15 females. Seventy-nine percent of the patients had suffered from epileptic fits, in 69% it was the presenting symptom.
Patient‑derived orthotopic xenograft glioma models fail to replicate the magnetic resonance imaging features of the original patient tumor.
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Patient‑derived orthotopic glioma xenograft models are important platforms used for pre‑clinical research of glioma. In the present study, the diagnostic ability of magnetic resonance imaging (MRI) was examined with regard to the identification of biomarkers obtained from patient‑derived glioma
Increased prevalence of obesity and obesity-related postoperative complications in male patients with meningiomas.
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OBJECTIVE
The female preponderance of meningiomas may reflect hormonal influences on meningioma growth. We hypothesized that because obesity affects male steroid hormone synthesis, male patients with meningiomas might exhibit a high obesity rate, which, in turn, might increase their frequency of
Anthropometrics and Body Composition in Adults with High-Grade Gliomas: Effects of Disease-Related Variables.
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Nutritional status in adults with high-grade gliomas (HGGs) has been poorly investigated. We studied anthropometrics and fat mass (FM), fat free mass (FFM), and body water in HGGs patients also in relation to disease-related variables. Fifty-one patients (17 III and 34 IV-grade) and fifty-one
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